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HPV

Detection of HPV Infection in Non-cancer Oesophageal Lesions and Normal Tissue by Nested Polymerase Chain Reaction

Issue: 
DOI: 
10.7727/wimj.2014.322
Pages: 
496-99
Synopsis: 
Human papilloma virus (HPV) can be the aetiologic factor in the benign or malignant oesophageal epithelium. Nested PCR was performed for detection of HPV in non-cancer oesophageal lesions. A third (33.7%) of samples were infected with HPV DNA. This can lead to cell changes that over many years may develop into cancer.

ABSTRACT

Accepted: 
05 Jan, 2015
PDF Attachment: 
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e-Published: 21 Jul, 2015

Knowledge and Perceptions of HPV and the HPV Vaccine among Pre-adolescent Girls and Their Guardians in Georgetown, Guyana

Issue: 
DOI: 
10.7727/wimj.2015.113
Pages: 
43–8
Synopsis: 
As the Ministry of Health in Guyana seeks to introduce human papillomavirus (HPV) vaccination, this study highlights the disparity between perceived knowledge and the correct knowledge of the stakeholders: the girls and their guardians. It also examines ways of overcoming this dilemma.
 ABSTRACT

Objectives: To examine the knowledge and perceptions of 11-year old girls and their guardians toward the  human papillomavirus (HPV), HPV (mandatory) vaccination and cervical cancer and to determine their main sources of health information.

Accepted: 
18 Mar, 2015
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Journal Sections: 
Journal Authors: 
e-Published: 28 Apr, 2015

Early Changes in Carcinogenesis of Colorectal Adenomas

Issue: 
Pages: 
10–6
Synopsis: 
Ki-67 expression both in the crypt-surface epithelium and cyclin D1, c-erb B2, bcl-2 over-expression may be a clue of dysplastic epithelium. If the role of human papillomavirus is elucidated in colonic carcinogenesis, vaccination might prevent carcinogenesis from the virus.

 

ABSTRACT

Objectives: Adenocarcinoma of the colon and rectum is the third most common cause of cancer deaths and the sixth most common cancer in the world. Adenomas are benign neoplastic lesions which can be transformed into carcinomas, but this is usually not the case. There should be some risk factors which lead to the development of carcinomas into adenomas. The aim of this study is to find out the early changes and high risk factors related to carcinogenesis in colonic polyps.

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Journal Sections: 
Journal Authors: 
e-Published: 19 Aug, 2013
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