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The Urinary Levels of Some Essential and Toxic Metals in Type 2 Diabetic Patients and Non-diabetic Healthy Control Human Subjects

DOI: 
10.7727/wimj.2016.134
Synopsis: 
Metals are central to hold the bioactivity of numerous enzymes and proteins on which life is based. Several previously published studies demonstrated the functions of transition and trace elements Fe, Zn, Mg, Cu, Mn and Cr in insulin action and carbohydrate metabolism. This study aimed to assess the interrelationship of some selected metals such as Mg, Zn, Cu, Cr, Mn, Pb, Ni and Fe in urines of T2D patients versus non-diabetic subjects. The findings of this study could provide a way to explore urinary metal-based marker(s) for disease pathogenesis and progression.

ABSTRACT

Objective: To compare the levels of some selected essential and toxic metals in type 2 diabetic (T2D) patients and non-diabetic (ND) healthy controls. Furthermore, study aims to evaluate the possible interrelationship of metals in urine of type 2 diabetic (T2D) patients and non-diabetic (ND) healthy controls.

Received: 
31 Mar, 2016
Accepted: 
29 Nov, 2016
PDF Attachment: 
PDF icon khan_et_al-derangement_of_urinary_metals_in_diabetes.pdf
Journal Sections: 
Original Articles
Keywords: 
Type 2 diabetes
urine
Essential and toxic metals
Journal Authors: 
AR Khan
FR Awan
K Akhter
M Islam
S Najam
M Zain
T Siddique
e-Published: 06 Dec, 2016

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Urine IL-8 is the Predictive Biomarker of Steroid Sensitivity in Patients with Idiopathic Nephrotic Syndrome

DOI: 
10.7727/wimj.2014.363
Synopsis: 
We conducted a prospective study on idiopathic nephrotic syndrome (INS) to explore the changes in the urine IL levels of the patients to discover the noninvasive indicators for predicting and dynamically monitoring steroid efficacy in the steroid therapy of INS patients.

ABSTRACT

Objective: The study aimed to explore the correlation between urine interleukin (IL)-8, 6, 10, 17 levels and the efficacy of steroid in patients with idiopathic nephrotic syndrome (INS).

Received: 
01 Dec, 2014
Accepted: 
12 Dec, 2014
PDF Attachment: 
PDF icon xie_et_al-urine_il-8_as_biomarker_of_steroid_sensitivity.pdf
Journal Sections: 
Original Articles
Keywords: 
Idiopathic nephrotic syndrome
interleukin
steroid resistance
urine
Journal Authors: 
H Xie
M Fang
H Lin
P Li
N Sun
J Chen
Y Sun
e-Published: 10 Aug, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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