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The Urinary Levels of Some Essential and Toxic Metals in Type 2 Diabetic Patients and Non-diabetic Healthy Control Human Subjects

DOI: 
10.7727/wimj.2016.134
Synopsis: 
Elevated level of metals in blood is reflected in urine of the human diabetic subjects. As an increased urinary excretion of metals causes decrease in blood plasma level of that particular metal and vice versa. Toxic metals such as Pb may have a role to induce renal tubular dysfunction in diabetic patients. Subsequently, dysfunctional kidneys may become a potential source for the loss of several essential TE through urine voiding rather than their retention in blood plasma /serum in order to retain the homeostasis of blood and other tissues.

ABSTRACT

Objective: To compare the levels of some selected essential and toxic metals in type 2 diabetic (T2D) patients and non-diabetic (ND) healthy controls. Furthermore, study aims to evaluate the possible interrelationship of metals in urine of type 2 diabetic (T2D) patients and non-diabetic (ND) healthy controls.

Accepted: 
29 Nov, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 06 Dec, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Urine IL-8 is the Predictive Biomarker of Steroid Sensitivity in Patients with Idiopathic Nephrotic Syndrome

DOI: 
10.7727/wimj.2014.363
Synopsis: 
We conducted a prospective study on idiopathic nephrotic syndrome (INS) to explore the changes in the urine IL levels of the patients to discover the noninvasive indicators for predicting and dynamically monitoring steroid efficacy in the steroid therapy of INS patients.

ABSTRACT

Objective: The study aimed to explore the correlation between urine interleukin (IL)-8, 6, 10, 17 levels and the efficacy of steroid in patients with idiopathic nephrotic syndrome (INS).

Accepted: 
12 Dec, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 10 Aug, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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