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C Fisher

Newborn Screening for Sickle Cell Disease: Jamaican Experience

Issue: 
DOI: 
10.7727/wimj.2015.492
Pages: 
18–26
Synopsis: 
The history and evolution of laboratory technology for newborn screening for sickle cell disease is reviewed with particular reference to Jamaica. The procedures and results of screening 54 566 newborns from southern and western Jamaica are presented.

ABSTRACT

Objectives:  To review the history of newborn screening for sickle cell disease with especial reference to Jamaica.

Methods: A summary of the history, the development of associated laboratory technology and the implementation of newborn screening for sickle cell disease in Jamaica.

Accepted: 
22 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 22 Sep, 2015

Homozygous Sickle Cell Disease in Uganda And Jamaica: A Comparison of Bantu and Benin Haplotypes

DOI: 
Doi:10.7727/wimj.2012.167

Objective: To compare the haematological and clinical features of homozygous sickle cell (SS) disease in Bantu and Benin haplotypes in a cross-sectional study of 115 Ugandan patients attending the Sickle Cell Clinic at Mulago Hospital, Kampala, Uganda, with 311 patients in the Jamaican Cohort Study.

Methods: This involved the comparison of clinical features and haematology with special reference to genetic determinants of severity including fetal haemoglobin levels, beta-globin haplotype, and alpha thalassaemia status.

PDF Attachment: 
Journal Sections: 
e-Published: 15 Feb, 2013

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Homozygous Sickle Cell Disease in Uganda and Jamaica: A Comparison of Bantu and Benin Haplotypes

Issue: 
DOI: 
Doi:10.7727/wimj.2012.167
Pages: 
684–91
Synopsis: 
Comparison of the Bantu and Benin haplotypes in Ugandan and Jamaican patients with homozygous sickle cell disease reveal some clinical and haemato-logical differences. Better documentation is needed to derive optimal models of care for Ugandan patients.

ABSTRACT

PDF Attachment: 
Journal Sections: 
e-Published: 01 Mar, 2013
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