This review follows the contributions of researchers from
the Caribbean in improving the understanding of the disease
mechanisms, clinical features and aetiology of neurological
syndromes manifesting as diseases of the spinal
cord and peripheral nerves. The link between the natural
history of human T-cell leukaemia/lymphoma virus type-1
(HTLV-1) infection and the immunopathogenesis of tropical
spastic paraparesis is explored.