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Histopathological and Immunohistochemical Study of the Effect of Sildenafil Citrate, Vitamin A, Vitamin C and Vitamin E on Wound Healing in Alloxan-induced Diabetic Rats

Issue:

Vol 69, Issue 5: 2021

DOI:

10.7727/wimj.2015.596

Pages:

332-7

Synopsis:

The aim of this study was to examine the impact of sildenafil citrate, vitamin A, vitamin C and vitamin E on wound healing in diabetics. It was decided that when it is necessary to recommend an ideal combination for the wound of a diabetic, it would be beneficial to use sildenafil citrate together with vitamin A and vitamin C.

ABSTRACT

Objective: To examine the impact of sildenafil citrate, vitamin A (Vit A), vitamin C (Vit C) and vitamin E (Vit E) on wound healing in a rat model of diabetes (n = 100).

Received:

10 Dec, 2015

Accepted:

07 Jan, 2016

Published:

12 Nov, 2021

PDF Attachment:

wimj-iss5-2021_332_337.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 16 Mar, 2017

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Histopathological Changes that Occur on the Testicular and Penile Tissues Depending on the Treatment of Human Chorionic Gonadotropin: Rat Model

Issue:

Vol 69, Issue 5: 2021

DOI:

10.7727/wimj.2015.282

Pages:

315-8

Synopsis:

Human chorionic gonadotropin (hCG) treatment may lead to deterioration in testicular histology and histological changes in the penile tissue. The degradation in the testicular tissue and the changes formed in the penile tissue may affect the erectile tissue function.

ABSTRACT

Objective: To examine the histopathological effects of human chorionic gonadotropin (hCG) treatment on the penile and the testicular tissue in rat model.

Received:

29 May, 2015

Accepted:

11 Sep, 2015

Published:

12 Nov, 2021

PDF Attachment:

wimj-iss5-2021_315_318.pdf

Journal Sections:

Original Articles

Keywords:

histopathology

human chorionic gonadotropin

Journal Authors:

e-Published: 22 Mar, 2016

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Rapamycin Improves Vascular Remodelling in a Controlled Rat Model of Monocrotaline-Induced Pulmonary Hypertension

Issue:

Vol 69, Issue 9: 2023

DOI:

10.7727/wimj.2015.222

Pages:

638-44

Synopsis:

We evaluated the effect of rapamycin on pulmonary arterial hypertension. Rapamycin provided improvements in exercise capacity, right ventricular systolic pressure and hypertrophy, but those were not significant. There were significant recoveries in the pulmonary artery muscular layer thickness and in the median life span of rats.

ABSTRACT

Background: Pulmonary arterial hypertension (PAH) is a serious disease characterized by the progressive elevation of the pulmonary arterial resistance, leading to the right ventricular failure and death. Objective: To evaluate the effect of rapamycin (RAPA), a potent cell-cycle inhibitor, on exercise capacity, right ventricular hypertrophy and pulmonary vascular remodelling on rats.

Received:

04 May, 2015

Accepted:

18 May, 2015

Published:

25 Jan, 2023

PDF Attachment:

wimj-iss9-2023_638_644.pdf

Journal Sections:

Original Articles

Keywords:

Life expectancy