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A Tas

Histopathological and Immunohistochemical Study of the Effect of Sildenafil Citrate, Vitamin A, Vitamin C and Vitamin E on Wound Healing in Alloxan-induced Diabetic Rats

Issue: 
DOI: 
10.7727/wimj.2015.596
Pages: 
332-7
Synopsis: 
The aim of this study was to examine the impact of sildenafil citrate, vitamin A, vitamin C and vitamin E on wound healing in diabetics. It was decided that when it is necessary to recommend an ideal combination for the wound of a diabetic, it would be beneficial to use sildenafil citrate together with vitamin A and vitamin C.

ABSTRACT

Objective: To examine the impact of sildenafil citrate, vitamin A (Vit A), vitamin C (Vit C) and vitamin E (Vit E) on wound healing in a rat model of diabetes (n = 100).

Accepted: 
07 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 16 Mar, 2017

Histopathological Changes that Occur on the Testicular and Penile Tissues Depending on the Treatment of Human Chorionic Gonadotropin: Rat Model

Issue: 
DOI: 
10.7727/wimj.2015.282
Pages: 
315-8
Synopsis: 
Human chorionic gonadotropin (hCG) treatment may lead to deterioration in testicular histology and histological changes in the penile tissue. The degradation in the testicular tissue and the changes formed in the penile tissue may affect the erectile tissue function.

ABSTRACT

Objective: To examine the histopathological effects of human chorionic gonadotropin (hCG) treatment on the penile and the testicular tissue in rat model.

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 22 Mar, 2016

Rapamycin Improves Vascular Remodelling in a Controlled Rat Model of Monocrotaline-induced Pulmonary Hypertension

DOI: 
10.7727/wimj.2015.222
Synopsis: 
We evaluated the effect of rapamycin on pulmonary arterial hypertension. Rapamycin provided improvements in exercise capacity, right ventricular systolic pressure and hypertrophy, but those were not significant. There were significant recoveries in pulmonary artery muscular layer thickness and in the medium lifespan of rats.

ABSTRACT

Objective: Pulmonary arterial hypertension (PAH) is a serious disease characterized by progressive elevation of pulmonary arterial resistance, leading to right ventricular failure and death. We aimed to evaluate the effect of rapamycin (RAPA), a potent cell-cycle inhibitor, on exercise capacity, right ventricular hypertrophy, and pulmonary vascular remodeling.

Accepted: 
18 May, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 13 Aug, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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