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C-reactive protein

Plasma Cellular Hypoxia, Mitochondrial Dysfunction, Disease Risk and Prognostic Factors in Type 2 Diabetic Patients in Saudi Arabia

Issue: 
DOI: 
10.7727/wimj.2017.117
Pages: 
262-73
Synopsis: 
This study investigated the level of plasma hypoxia-inducible factor (HIF)-1α and cytochrome c (CytoC) in correlation with C-reactive protein, dyslipidaemia, insulin resistance, and prognostic factors in Type 2 diabetic patients in Saudi Arabia. Reduced level of HIF-1α and non-significant increased level of CytoC correlated negatively with these prognostic factors. These results pointed to a possible pathogenetic implication for HIF-1α.

ABSTRACT

Objective: This cross-sectional study evaluated the association of plasma cytochrome c (CytoC) and hypoxia-inducible factor (HIF)-1α, as mitochondrial dysfunction and cellular hypoxia biomarkers, with disease risk factors and prognosis in Type 2 diabetic patients in Saudi Arabia.

Accepted: 
30 Jun, 2017
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e-Published: 21 Aug, 2017

Phototherapy Induces an Improvement in Clinical and Biochemical Scores in Patients with Rheumatoid Arthritis

Issue: 
DOI: 
10.7727/wimj.2015.490
Pages: 
21-5
Synopsis: 
Rheumatoid arthritis is a common autoimmune disease for which there is no known cure. Within a range of 425–650 nm and 11.33 J/cm2, phototherapy can induce an improvement in clinical and laboratorial variables in patients with rheumatoid arthritis.

ABSTRACT

Objective: Rheumatoid arthritis (RA) is a common autoimmune disease for which there is no known cure. Ultraviolet light can induce immunosuppressive effects. Our main objective was to ascertain whether a complementary treatment with phototherapy would improve changes in functional scales in patients with RA.

Methods: Seven women with RA were enrolled for this study and submitted to phototherapy sessions with a 425–650 nm lamp.

Accepted: 
30 Sep, 2015
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e-Published: 15 Mar, 2016

The Effect of Interleukin 23 Levels on Clinical and Laboratory Parameters of Patients with Ankylosing Spondylitis

Issue: 
DOI: 
10.7727/wimj.2015.241
Pages: 
222-6
Synopsis: 
Ankylosing spondylitis is a progressive disease that should be monitored routinely throughout a patient’s life. IL-23 should be used as a clinical marker, and the findings can be strengthened by the combined information obtained from Ankylosing Spondylitis activity indexes analyses.

ABSTRACT

Objective: In the present study, we aimed to investigate the relationship between interleukin 23 (IL-23) and the clinical and laboratory parameters in patients with ankylosing spondylitis (AS). Ankylosing spondylitis causes structural and functional inability, particularly in the axial skeleton, and results in the inflammatory lower back pain. At the same time, we aimed to investigate the relationship between IL-23 levels and disease related variables in patients with AS.

Accepted: 
12 Aug, 2015
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e-Published: 29 Dec, 2015

C-reactive Protein: Adjunct to Cardiovascular Risk Assessment

Issue: 
Pages: 
551–5
Synopsis: 
Prevention of cardiovascular disease is well-described. However, a significant gap lies in the detection of at-risk persons who should be targeted for intervention. Can C-reactive protein be an effective adjunct to cardiovascular risk assessment.

ABSTRACT

Objectives: The study aimed to investigate whether elevated plasma high sensitivity C-reactive protein (hs-CRP) levels are independently associated with an increased risk of cardiovascular disease (CVD) and to then assess the effectiveness of the addition of hs-CRP testing to cardiovascular risk assessment by standard lipid screening.

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e-Published: 20 Sep, 2013

Estimation of the Levels of C-reactive Protein, Interleukin-6, Total Leukocyte Count, and Differential Count in Peripheral Blood Smear of Patients with Chronic Periodontitis in a South Indian Population

Issue: 
DOI: 
Doi:10.7727/wimj.2011.096
Pages: 
826–31
Synopsis: 
Periodontitis results in higher systemic levels of C-reactive protein, interleukin-6, total leukocyte count and neutrophils. These elevated inflammatory factors may increase inflammatory activity in atherosclerotic lesions, potentially increasing the risk for cardiovascular events.

ABSTRACT

Aims: The aim of the present study is to investigate systemic levels of inflammatory markers of cardiovascular diseases like C-reactive protein (CRP), interleukin-6 (IL-6), total leukocyte count and differential count in patients with chronic periodontitis, in comparison to healthy individuals without periodontal disease.

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e-Published: 21 Jan, 2013
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