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hydroxyurea

Effect of Hydroxyurea on Priapism in Men with Sickle Cell Disease

Issue: 
DOI: 
10.7727/wimj.2016.326
Pages: 
518–20
Synopsis: 
This report represents a retrospective case series of males with sickle cell disease who have recurrent episodes of ischaemic priapism and were being treated with hydroxyurea for other indications. We evaluated the changes in priapism episodes in these patients.

ABSTRACT

Accepted: 
14 Oct, 2016
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Journal Sections: 
Journal Authors: 
e-Published: 25 Oct, 2016

The Effect of Hydroxyurea therapy on Adverse Clinical Events and Haematological Indices in Paediatric Patients with Sickle Cell Anaemia

Issue: 
DOI: 
10.7727/wimj.2015.538
Pages: 
80–85
Synopsis: 
The vast majority of available evidence on the efficacy, effectiveness and safety of hydroxyurea in childhood sickle cell anaemia (SCA) is mostly from high-income countries. The conclusions drawn from this study would be useful in guiding hydroxyurea use in other less developed countries with limited resources.

ABSTRACT

Objective: The aim of this study was to determine the effect of Hydroxyurea on adverse clinical events and haematological indices in paediatric patients with sickle cell anaemia.

Method: This study compared the same cohort of patients before and after Hydroxyurea therapy monitoring the rate of adverse events pre and post treatment and haematological indices.

Accepted: 
17 Nov, 2015
Journal Sections: 
e-Published: 31 Mar, 2016
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