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Lung Cancer

Correlation between Pokemon and Mouse Double Minute 2-Homolong in Carcinogenesis of Lung Squamous Cell Carcinoma in Rats

Issue: 
DOI: 
10.7727/wimj.2016.252
Pages: 
603-7
Synopsis: 
This research was to investigate the correlation between proto-oncogene POK erythroid myeloid ontogenic factor (Pokemon) and oncogene mouse double minute 2 homolong (MDM2). We found that Pokemon and MDM2 were highly expressed in rat lungs following carcinogenesis of lung squamous cell carcinoma.

ABSTRACT 

Accepted: 
22 Aug, 2016
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Journal Sections: 
e-Published: 03 Feb, 2017

Abdominal Apoplexy after Pulmonary Lobectomy for Lung Cancer

Issue: 
DOI: 
10.7727/wimj.2016.064
Pages: 
289-91

ABSTRACT

Abdominal apoplexy is a rare clinical entity, and its clinical manifestations are diverse. This case report is of a 52-year-old man who developed right upper abdominal pain with unstable haemodynamics 32 hours after right upper pulmonary lobectomy for lung carcinoma. Abdominal computed tomography showed a ruptured right gastric artery aneurysm.

Accepted: 
20 Apr, 2016
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Journal Sections: 
e-Published: 25 Apr, 2016

Primary Endobronchial Leiomyoma

DOI: 
10.7727/wimj.2015.567

ABSTRACT

Leiomyoma accounts for less than 2% of the benign tumours of the lung. These lesions are usually asymptomatic. However, they can present symptoms depending on the localization. The HRCT of a 57-year-old male patient with cough, sputum and shortness of breath ongoing for 2 months revealed a 5 mm lesion in the inferior lingular bronchus. The report of the bronchoscopic biopsy was leiomyoma, and the patient underwent lingulectomy.

Accepted: 
07 Dec, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 29 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Cigarette Smoking Increases Pregnancy-associated Plasma Protein-A in Men

Issue: 
DOI: 
10.7727/wimj.2014.371
Pages: 
150–3
Synopsis: 
Elevation of pregnancy-associated plasma protein-A (PAPP-A), is considered as an independent risk factor for acute coronary syndrome (ACS). We found significantly high PAPP-A level in the serum of male smokers and this may indicate a higher risk for ACS among these men.

ABSTRACT

Accepted: 
07 Jan, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 30 Jul, 2015

Cassia alata Leaf Extract Induces Cytotoxicity in A549 Lung Cancer Cells via a Mechanism that is Caspase 8 Dependent

Issue: 
Pages: 
608–14
Synopsis: 
The cytotoxic effect of a hexane extract of Cassia alata (C alata) leaves in parental and Caspase 8, 3 and 9 negative A549 lung cancer cells was evaluated after a 24-hour treatment period. C alata extract was cytotoxic in parental and caspase-9 negative, but not caspase 3 and 8 negative A549 cells. The IC50 values were 143 μg/ml and 145 μg/ml in parental and caspase 9 negative A549 cells respectively. The flavanoid kaempferol was identified as a constituent of C alata leaf extract. These results suggest a cytotoxic effect of C alata that is dependent on caspase 8.
 
 
ABSTRACT
 
Objective: To evaluate the cytotoxic effect of a hexane extract of Cassia alata leaves in A549 lung cancer cells.
 
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Journal Sections: 
Journal Authors: 
e-Published: 03 Feb, 2014

Correlation between Pokemon and MDM2 in Carcinogenesis of Lung Squamous Cell Carcinoma in Rats

DOI: 
10.7727/wimj.2016.252
Synopsis: 
This research was to investigate correlation between proto-oncogene POK erythroid myetoid ontogenic factor (Pokemon) and oncogene MDM2. We found that Pokemon and MDM2 were highly expressed in rat lungs following carcinogenesis of lung squamous cell carcinoma.

ABSTRACT

Accepted: 
22 Dec, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 06 Dec, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Metastatic Lung Cancer Presenting as Thoracic Empyema in an Old Patient

Issue: 
DOI: 
10.7727/wimj.2013.291
Pages: 
514–6

ABSTRACT

Accepted: 
30 Oct, 2013
PDF Attachment: 
Journal Sections: 
e-Published: 20 Jun, 2014

Trends in Incidence and Histological Subtypes of Lung Cancer, Kingston and St Andrew, Jamaica, 1968–1997

Issue: 
Pages: 
13–18
Synopsis: 
A 30-year review of lung cancers from Kingston and St Andrew, Jamaica, shows a progressive shift in the distribution of histological subtypes, mirroring similar trends that have been documented worldwide.

ABSTRACT

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Journal Sections: 
e-Published: 06 Jun, 2013

The Importance of Smoking Cessation as Part of Lung Cancer Control Measures in Japan

Issue: 
Pages: 
726

INTRODUCTION

A study of annual trends in the number of deaths and mortality rate in Japan found that lung cancer is one of the most frequent causes of death (1). Lung cancer is clearly associated with cigarette smoking (2). Thus, this paper reviews reports on the importance of measures to stop smoking as part of lung cancer control measures in Japan and it discusses how these findings can be linked to more specific preventive measures.

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Journal Sections: 
Journal Authors: 
e-Published: 15 Oct, 2013
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