The immune reconstitution inflammatory syndrome (IRIS) is a recognized complication associated with opportunistic infections occurring in HIV-infected individuals after the initiation of highly active antiretroviral therapy (HAART). We report on three HIV-infected infants with rapid progressor HIV disease who present with IRIS due to the BCG vaccine and occurring 3–6 weeks after initiation of HAART.
Objective: Paediatric HIV is a leading cause of morbidity and mortality worldwide. We describe HIVrelated mortality in a cohort of HIV-infected Jamaican children and identified factors which influenced survival.
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The majority of strains of HIV-1 isolated from HIV-1 infected individuals in Jamaica were found to be HIV- 1 subtype B. The less frequently found HIV-1 subtypes were C, D and E and some strains were untypable by the methods used.