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RB Pierre

Trends of Microcephaly and Severe Arthrogryposis in Three Urban Hospitals following the Zika, Chikungunya and Dengue Fever Epidemics of 2016 in Jamaica

Issue: 
DOI: 
10.7727/wimj.2017.124
Pages: 
10–9
Synopsis: 
Newborns with the characteristics of congenital syndrome associated with Zika virus (CSAZ) are being born in urban hospitals after the 2016 Zika virus epidemic in Jamaica. Phenotypic features include microcephaly, craniofacial disproportion, neuro-imaging and neuro-pathological findings and arthrogryposis. A trend towards babies being delivered with small head circumferences, but not yet in the range of microcephaly and others with normal head sizes who were born to women who were symptomatic in pregnancy is also being observed. While, most babies with probable CSAZ are being born to asymptomatic women who did not report any symptoms related to arbovirus illness in pregnancy. Diagnosis is challenged by serological cross-reactivity between circulating flaviviruses. Team management is multidisciplinary to maximize the neuro-developmental potential of this vulnerable patient population.
ABSTRACT
 
Introduction: Jamaica experienced its maiden Zika virus (ZIKV) epidemic in 2016, while dengue (serotypes 3 and 4) and chikungunya were also circulating.
 
Aim: We describe initial trends in microcephaly and arthrogryposis observed by the clinicians from three urban birthing facilities during late 2016 to early 2017.
Accepted: 
12 Jun, 2017
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e-Published: 12 Jun, 2017

Antibiotic Resistance among Pathogens Causing Disease in Jamaican Children with HIV/AIDS

Issue: 
Pages: 
386–92
Synopsis: 
The prevalence and antibiotic susceptibility patterns of pathogens causing urinary tract infections (UTIs) and sepsis in a cohort of HIV positive Jamaican children was determined. Cotrimoxazole is a poor choice for empiric treatment of sepsis and UTIs in this cohort.

ABSTRACT

Objective: There are limited data regarding the antimicrobial resistance patterns of pathogens in children with HIV/AIDS from developing countries. We aimed to determine the prevalence and antibiotic susceptibility patterns of bacterial pathogens causing urinary tract infections (UTIs) and sepsis in a cohort of 219 HIV-infected Jamaican children.

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e-Published: 07 Oct, 2013

Students’ Perception of the ‘Educational Climate’ at the Faculty of Medical Sciences, The University of the West Indies, Jamaica

Issue: 
Pages: 
45–9
Synopsis: 
The Dundee Education Environment Measure was self-administered in 2004 to undergraduate medical students in the Faculty of Medical Sciences, Mona, Jamaica. The students-centredness and friendliness of the educational environment needs to be optimized.

ABSTRACT

Background: In 2001, the Faculty of Medical Sciences at the Mona Campus of The University of the West Indies (UWI) introduced a restructured curriculum in keeping with advances in the philosophy of medical education.

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e-Published: 01 Oct, 2013

Eliminating Vertically-transmitted HIV/AIDS while Improving Access to Treatment and Care for Women, Children and Adolescents in Jamaica

Issue: 
Pages: 
396–404
Synopsis: 
Over the past nine years, Jamaica has made excellent strides to eliminate vertically transmitted HIV/AIDS, while reducing the HIV-attributable morbidity and mortality in pregnant women and in HIV-infected children. Continued successful transition of HIV-infected children through adolescence into adulthood will require a strong multidisciplinary team approach.

ABSTRACT

Background and Methods: To celebrate Jamaica’s 50th birthday after receiving independence from Great Britain, we summarize our collaborative published research in the prevention, treatment and care of paediatric, perinatal and adolescent HIV/AIDS in Jamaica.

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e-Published: 21 Aug, 2013

Bacille Calmette-Guérin Lymphadenitis and Immune Reconstitution Syndrome in HIV-infected Children on Antiretroviral Therapy in Jamaica

Issue: 
Pages: 
302–6

ABSTRACT

The immune reconstitution inflammatory syndrome (IRIS) is a recognized complication associated with opportunistic infections occurring in HIV-infected individuals after the initiation of highly active antiretroviral therapy (HAART). We report on three HIV-infected infants with rapid progressor HIV disease who present with IRIS due to the BCG vaccine and occurring 3–6 weeks after initiation of HAART.

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e-Published: 19 Jul, 2013

Isoniazid-resistant Disseminated Mycobacterium Tuberculosis in a Jamaican Infant with HIV/AIDS

Issue: 
Pages: 
298–301

ABSTRACT

A case report of isoniazid-resistant disseminated tuberculosis in a young child perinatally co-infected with human immunodeficiency virus (HIV-1) and the challenges managing this child in a resource-constrained setting.

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e-Published: 19 Jul, 2013

Predictors of HIV/AIDS Confirmation and Differences by Guardian Status in HIV+ Adolescents in Jamaica

Issue: 
Pages: 
287–92

ABSTRACT

Background: Approximately 25% of the cumulative AIDS cases in Jamaica involve adolescents and young adults. However, the lives of adolescents living with HIV within Jamaica and the Caribbean have been understudied.

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e-Published: 19 Jul, 2013

HIV-related Mortality in Jamaican Children

Issue: 
Pages: 
265–8

ABSTRACT

Objective: Paediatric HIV is a leading cause of morbidity and mortality worldwide. We describe HIVrelated mortality in a cohort of HIV-infected Jamaican children and identified factors which influenced survival.

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e-Published: 19 Jul, 2013

Clinical Manifestations of Adolescents with HIV/AIDS in Jamaica

Issue: 
Pages: 
257–64

ABSTRACT

Objective: To characterize the clinicopathological manifestations and outcomes of a cohort of HIV-infected Jamaican adolescents.

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e-Published: 19 Jul, 2013

Renal Manifestations in HIV-infected Jamaican Children

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