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Special Articles

Trends of Microcephaly and Severe Arthrogryposis in Three Urban Hospitals following the Zika, Chikungunya and Dengue Fever Epidemics of 2016 in Jamaica

Issue: 
DOI: 
10.7727/wimj.2017.124
Pages: 
10–9
Synopsis: 
Newborns with the characteristics of congenital syndrome associated with Zika virus (CSAZ) are being born in urban hospitals after the 2016 Zika virus epidemic in Jamaica. Phenotypic features include microcephaly, craniofacial disproportion, neuro-imaging and neuro-pathological findings and arthrogryposis. A trend towards babies being delivered with small head circumferences, but not yet in the range of microcephaly and others with normal head sizes who were born to women who were symptomatic in pregnancy is also being observed. While, most babies with probable CSAZ are being born to asymptomatic women who did not report any symptoms related to arbovirus illness in pregnancy. Diagnosis is challenged by serological cross-reactivity between circulating flaviviruses. Team management is multidisciplinary to maximize the neuro-developmental potential of this vulnerable patient population.
ABSTRACT
 
Introduction: Jamaica experienced its maiden Zika virus (ZIKV) epidemic in 2016, while dengue (serotypes 3 and 4) and chikungunya were also circulating.
 
Aim: We describe initial trends in microcephaly and arthrogryposis observed by the clinicians from three urban birthing facilities during late 2016 to early 2017.
Accepted: 
12 Jun, 2017
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Journal Sections: 
e-Published: 12 Jun, 2017

Chikungunya in Jamaica – Public Health Effects and Clinical Features in Children

Issue: 
DOI: 
10.7727/wimj.2016.529
Pages: 
431-37
Synopsis: 
The Chikungunya Fever epidemic had significant public health and economic impact in Jamaica. In children, there were characteristic presentations in neonates and young infants and in children six months to six years. Neurologic involvement was common but other organ dysfunction was rare.

ABSTRACT

Background: Chikungunya virus entered the Caribbean for the first time in 2013 and Jamaica experienced its maiden epidemic with Chikungunya Fever in 2014. We aimed to describe the public health effects and describe the clinical features in children and adolescents in Jamaica.

Accepted: 
26 Oct, 2016
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e-Published: 26 Oct, 2016

Outcome of Dengue in Hospitalized Jamaican Children

Issue: 
DOI: 
10.7727/wimj.2016.525
Pages: 
442-49
Synopsis: 
Before the emergence of Zika in 2016 and Chikungunya in 2014, there have been numerous dengue outbreaks in the Caribbean. Despite this, there is a paucity of published studies on dengue in children from this region. The potential for exponential spread of the Aedes aegypti dengue vector and its deleterious outcomes in children underlines the importance of this paper.

ABSTRACT

Background: Dengue fever is hyper-endemic in Jamaica with exponential rates of infection in successive outbreaks. The absence of local data and the potential for massive outbreaks in a country where a third of the population are children formed the basis for this study. 

Accepted: 
26 Oct, 2016
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e-Published: 26 Oct, 2016

Acute Paralysis and Neuro-inflammation in Jamaican Children during Zika virus and Dengue Epidemics of 2016

Issue: 
DOI: 
10.7727/wimj.2016.526
Pages: 
425-30
Synopsis: 
This case series suggests a unique clinical pattern of neuro-inflammation in Jamaican adolescents occurring during the ZIKV epidemic and questions the role of the three circulating arboviruses in the pathogenesis.

ABSTRACT

Accepted: 
24 Oct, 2016
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e-Published: 25 Oct, 2016

Zika Outbreak Associated Neurological Syndromes in Jamaica

Issue: 
DOI: 
10.7727/wimj.2016.511
Pages: 
438-41
Synopsis: 
The Zika outbreak and its potential association with severe neurological syndromes was declared a public health emergency by the World Health Organization. An abrupt increase in the incidence of otherwise infrequent acute neurological syndromes is described in Jamaica.

ABSTRACT

Objective: To describe the demographic, clinical and laboratory features and, treatment and outcomes of Zika outbreak associated neurological syndromes.

Accepted: 
24 Oct, 2016
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Journal Authors: 
e-Published: 25 Oct, 2016

Rapid Diagnosis of Dengue Outbreaks in Resource Limited Facilities

Issue: 
DOI: 
10.7727/wimj.2016.095
Pages: 
4–9
Synopsis: 
The study evaluated a combined antigen-antibody based test for rapid, sensitive and specific diagnostic methodology comparable to polymerase chain reaction. The approach was found to be highly sensitive, specific, user-friendly, compact, frugal and thus, suitable for use in dengue outbreaks, field conditions and as bed-side diagnostic tests, for confirmation of dengue outbreaks in resource-limited facilities.
ABSTRACTS
 
Accepted: 
25 May, 2016
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e-Published: 06 Jul, 2016

Exploring Exposure and Symptomatic Differences of Chikungunya Virus in the Adult Population of Grenada

Issue: 
DOI: 
10.7727/wimj.2015.408
Pages: 
20–4
Synopsis: 
Primary data were collected to examine symptomatic differences by age group and to assess differences between those exposed and unexposed to chikungunya virus.

ABSTRACT

Accepted: 
11 Sep, 2015
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Journal Sections: 
Journal Authors: 
e-Published: 08 Mar, 2016
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