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Original Articles

An Observational Study of Intraoperative Transfusion Management in a Cardiac Surgical Unit in Trinidad and Tobago

Issue: 
DOI: 
10.7727/wimj.2011.150
Pages: 
587–91
Synopsis: 
This observational study investigated intraoperative transfusion requirements in off-pump coronary artery bypass grafting and the cost implication of this versus the best practice of cell salvage techniques on a background of limited resources.

Objective: To investigate the intraoperative transfusion requirements in off-pump coronary artery bypass grafting (OPCABG) and the cost implication of blood products and cell savers on a background of limited resources.

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e-Published: 24 Jan, 2013

Evaluating a Theory-based Health Education Intervention to Improve Awareness of Prostate Cancer among Men in Western Jamaica

Issue: 
DOI: 
10.7727/wimj.2011.122
Pages: 
580–6
Synopsis: 
Use of a theory-based health educational intervention positively influenced knowledge of prostate cancer risk factors, symptoms, and types of screenings. This theory-based patient education programme can be replicated to promote awareness of prostate cancer and inform screening methods including potential risk associated with screening behaviours.

ABSTRACT

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e-Published: 24 Jan, 2013

Intensive Insulin Therapy in Severe Acute Pancreatitis: AMeta-analysis and Systematic Review

Issue: 
DOI: 
10.7727/wimj.2011.176
Pages: 
574–9
Synopsis: 
In patients with severe acute pancreatitis, intensive insulin therapy was superior to conventional insulin therapy in controlling blood glucose and it improved the final outcomes.

Objective: To assess the effect of intensive insulin therapy on outcomes of patients with severe acute pancreatitis.

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e-Published: 24 Jan, 2013

Paraoxonase 1 Status in Keratoconus: A Preliminary Study of Activity and Polymorphism

Issue: 
DOI: 
10.7727/wimj.2011.044
Pages: 
569–73
Synopsis: 
Keratoconic patients have reduced paraoxonase activity, which suggests that keratoconic corneas are more susceptible to oxidative stress. Reduced paraoxonase activity and keratoconus status appear to be associated with ethnicity.

ABSTRACT

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e-Published: 24 Jan, 2013

Seroprevalence of Trypanosoma cruzi in Blood Donors at the National Blood Transfusion Services―Guyana

Issue: 
DOI: 
10.7727/wimj.2009.110
Pages: 
559–63
Synopsis: 
The aim of this study was to determine the prevalence of Trypanosoma cruzi (T cruzi) in the blood donor population of the Guyana National Blood Transfusion Services. The study indicates that 1 in 286 donations or 0.35% tested positive for T cruzi antibodies in the national blood supply and it is recommended that continued blood screening be required to prevent further transmission.

Introduction: Blood transfusion is an important transmission route of Trypanosoma cruzi (T cruzi), a major parasitic infection in Central and South America. The limited treatment options are most effective in acute Chagas’ infection. At present, there is no current data on the prevalence of T cruzi in the blood donor population of Guyana. This information is necessary to protect the supply of the blood donation programme.

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e-Published: 24 Jan, 2013

Prevalence of the Metabolic Syndrome in Patients Presenting to the University Hospital of the West Indies: A Need to Adopt Proactive Screening and Specific Management Policy

Issue: 
DOI: 
10.7727/wimj.2011.220
Pages: 
802–8
Synopsis: 
The prevalence of metabolic syndrome in a group of adult psychiatric patients at the University Hospital of the West Indies was 28.9% and could represent a pathway to the future development of Type 2 diabetes mellitus and cardiovascular disease. Screening and continuous monitoring will allow for early intervention and possibly prevention of increased morbidity and mortality in this vulnerable population.

ABSTRACT

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e-Published: 21 Jan, 2013

The Prevalence and Significance of Oestrogen Receptor (ER) Positivity in Breast Cancer at the University Hospital of the West Indies, Jamaica

Issue: 
DOI: 
10.7727/wimj.2012.121
Pages: 
795–801
Synopsis: 
Oestrogen receptor (ER) status was positive in 125 (63%) and negative in 74 (37%) patients diagnosed with breast cancer. By comparing the cohorts of ER negative to ER positive patients, one can accurately identify which clinical variables bear clinical significance in this population and are affected by ER status, as well as impact patient outcome.

ABSTRACT

 Objective:  To identify the prevalence of oestrogen receptor (ER) positivity, and determine the relationship of ER status with patient and tumour characteristics, in patients with breast cancer.

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e-Published: 21 Jan, 2013

Anticardiolipin Antibodies and Lupus Anticoagulants among Women Undergoing In Vitro Fertilization in Jamaica

Issue: 
DOI: 
10.7727/wimj.2011.224
Pages: 
789–94
Synopsis: 
Approximately 8% of the infertile women seeking in vitro fertilization in Jamaica were anticardiolipin antibody and/or lupus anticoagulant positive. The presence of these antibodies did not affect the fertilization rate, pregnancy rate, nor did it demonstrate an increased risk for cycle cancellation or the ovarian hyperstimulation syndrome.

ABSTRACT

Objective:  The aims of this study were to evaluate the effect of anticardiolipin antibody (aCL) and lupus anticoagulant (LA) on the outcome of the in vitro ferlitization (IVF) cycles and to determine the prevalence of these antibodies in infertile women seeking IVF in Jamaica.

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e-Published: 21 Jan, 2013

Plasmid-mediated Fluoroquinolone-resistance QnrA and QnrB Genes among Escherichia coli from Cattle in Ado-Ekiti, Nigeria

Issue: 
DOI: 
10.7727/wimj.2012.101
Pages: 
784–8
Synopsis: 
Fluoroquinolones are antibiotics of choice for treatment of infections in humans and are also increasingly used sub-therapeutically in veterinary practices. Seventeen plasmid-carrying fluoroquinolone-resistant representative isolates of commensal E coli recovered in a previous study from faeces of apparently healthy cattle in Ado-Ekiti, Nigeria, were investigated for the presence of qnrA and qnrB genes on plasmids using polymerase chain reaction.

ABSTRACT

Objective: This is to investigate the implication of fluoroquinolone usage in veterinary practice and the food chain system.

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e-Published: 21 Jan, 2013

Proteins and Liver Function Changes in Rats Following Cumulative Total Body Irradiations

Issue: 
DOI: 
10.7727/wimj.2011.174
Pages: 
773–7
Synopsis: 
Cumulative total body irradiation caused subtle but significant changes in liver function enzymes and proteins which may be due to non-specific stress reactions; as such they are important markers in radiation induced injury diagnosis.

ABSTRACT

Objective: Total body irradiation (TBI) is a choice therapy for the management of some malignancies; it is also a major cause of oxidative stress. The aim of this research is to sequentially document the effect of total body radiation on body function utilizing the sequential changes in liver function enzymes and proteins in rats.

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e-Published: 21 Jan, 2013

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