Patients from two tertiary referral hospitals were assessed to determine whether Type 2 diabetes mellitus was present in Jamaican diabetic youth. Type 2 diabetes accounted for 22% of cases. Obesity was the most important clinical predictor of Type 2 diabetes.
Objectives: To assess the frequency of youth onset Type 2 diabetes mellitus (T2D) in Jamaica and the characteristics of youth with this form of diabetes.
This issue of the Journal is devoted to HIV/AIDS; a follow-up to the first Special Issue on HIV/AIDS in Adults (1). There have been two productions in Paediatric AIDS (2, 3). There is a wide cross-section of articles on HIV/AIDS in this issue.
In this special issue of the Journal on the Human Immunodeficiency Virus (HIV), there are various articles dealing mostly with HIV in the adult and covering a varied spectrum. This compilation of articles gives a broad view of some of the psychosocial and clinical aspects of HIV in the Caribbean and other countries eg Nigeria, Botswana, China and Greece.
Epingaione (4-Methyl-1-(5-methyl-2,3,4,5-tetrahydro-[2,3’]bifuranyl-5-yl)-pentan-2-one) was isolated as one of the major lipophilic secondary metabolites from the leaves and stems of Bontia daphnoides L. The compound gave 79.24% and 50.83% anti-proliferation/cytotoxic activity on the human SH-SY5Y neuroblastoma and TE-671 sarcoma cells in vitro at 50 μg/mL, respectively. Epingaione was transformed into eleven derivatives under laboratory conditions using ethanol, some gave greater anti-proliferation/cytotoxic activity on the cancer cell lines tested.
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