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In Vitro Anti-Proliferation/Cytotoxic Activity of Epingaione and its Derivatives on the Human SHSY5Y Neuroblastoma and TE-671 Sarcoma cells

Issue: 
Pages: 
5–10
Synopsis: 
The present article evaluates the in vitro antiproliferation/ cytotoxic activity of Epingaione and selected derivatives isolated from Bontia daphnoides L on the human SH-SY5Y neuroblastoma and TE-671 sarcoma cells.

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e-Published: 01 Jul, 2013

Human Immunodeficiency Virus Type-1 (HIV-1) Subtypes in Jamaica

Issue: 
Pages: 
279–82
Synopsis: 
The majority of strains of HIV-1 isolated from HIV-1 infected individuals in Jamaica were found to be HIV- 1 subtype B. The less frequently found HIV-1 subtypes were C, D and E and some strains were untypable by the methods used.

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e-Published: 06 Jun, 2013

The Creation and Validation of the Jamaican Personality Disorder Inventory

Issue: 
DOI: 
10.7727/wimj.2013.211
Pages: 
389–96
Synopsis: 
The creation and validation of the 38-question Jamaica Personality Disorder Inventory (JPDI) screening questionnaire for the diagnosis of personality disorder piloted on patients from psychiatric and medical wards at the University Hospital of the West Indies is described.

ABSTRACT

Objective: To describe the creation and validation of the Jamaica Personality Disorder Inventory (JPDI) screening questionnaire.

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e-Published: 26 Aug, 2013

Nutritional Markers in Patients undergoing Chronic Haemodialysis in Jamaica

Issue: 
Pages: 
284–9
Synopsis: 
This study found that eighty per cent of patients on chronic haemodialysis had moderate malnutrition. Factors associated with malnutrition in patients on dialysis were having end-stage renal disease secondary to diabetes mellitus, dialysis duration for ≤ six months, low serum albumin, pre-dialysis serum creatinine of less than 880 μmol/L, low total cholesterol and presence of arteriovenous fistula access.

ABSTRACT

Objectives: The main objective of the study is to assess the nutritional status in patients on chronic haemodialysis in Jamaica using the Subjective Global Assessment tool and to correlate this with measured serum nutritional biomarkers, and also to identify nutritional biomarkers that can be used to assess nutritional status of patients with end-stage renal disease (ESRD).

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e-Published: 21 Aug, 2013

Immunological Evidence Supporting the Use of Extracts From Boehmeria jamaicensis Urb for Treating the Common Cold and Sinus Infections

Issue: 
Pages: 
487–90
Synopsis: 
Extracts of Boehmeria jamaicensis stimulated gamma interferon and may have implications for the treatment of the common cold.

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e-Published: 04 Jul, 2013

A Critical Review of the Therapeutic Potential of Dibenzyl Trisulphide Isolated from Petiveria alliacea L (Guinea hen weed, anamu)

Issue: 
Pages: 
17–21
Synopsis: 
The manuscript reviewed the 12 yrs (1992 – 2004) of research done on dibenzyl trisulphide (DTS) as a potential therapeutic agent. These studies revealed that DTS could be useful in the treatment of cancers, immunological disorders and memory loss.

ABSTRACT

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e-Published: 01 Jul, 2013

Depression among Persons Attending a HIV/AIDS Outpatient Clinic in Kingston, Jamaica

Issue: 
Pages: 
369–73
Synopsis: 
This paper reports on the prevalence of depression among patients attending a HIV/AIDS outpatient clinic in Kingston, Jamaica. It also explores the possible role of a number of clinical and socio-demographic factors in the relationship between HIV and depression. Recommendations for enhancing the timely detection of depression among persons living with HIV/AIDS are also discussed.

ABSTRACT

Objectives: To determine the prevalence of depression among persons attending a HIV/AIDS clinic in Kingston, Jamaica, and to explore the possible role of patient-specific clinical and social issues as intermediary factors in the relationship between HIV/ AIDS and depression.

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e-Published: 07 Oct, 2013

Validation of the Beck Depression Inventory II in HIV-positive Patients

Issue: 
Pages: 
374–9
Synopsis: 
The Beck Depression Inventory–ΙΙ is one of the gold standard screening tools for depression. It was validated in a sample of HIV-positive patients in Jamaica. The scale has reasonably good concurrent validity and acceptable discriminant validity.

                                                      ABSTRACT

Objective: Research on depression among HIV-positive patients has been limited by the lack of a valid and reliable measure of depression. This project addresses this problem by exploring the internal consistency reliability and the concurrent and discriminant validity of the Beck Depression Inventory-II (BDI-II) using HIV-positive patients in Jamaica.

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e-Published: 07 Oct, 2013

Cardiovascular Risk Profile in Caribbean Youth with Diabetes Mellitus

Issue: 
Pages: 
219–26
Synopsis: 
In this study, there was a high prevalence of cardiovascular risk factors in the patients studied regardless of their diabetes type. While patients with Type 2 diabetes mellitus were more obese and had higher blood pressure readings when compared with those with Type1 diabetes, their overall glucose control was better. Differences in lipid profile were no longer significant after adjusting for BMI.

ABSTRACT

Objective: To assess the effect of diabetes mellitus type on conventional and novel cardiovascular risk factors in patients, diagnosed with diabetes from two major referral hospitals in Jamaica, before age 25 years and with diabetes duration < 6 years.

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e-Published: 18 Sep, 2013

Antinuclear Antibodies and HLA Class II Alleles in Jamaican Patients with Systemic Lupus Erythematosus

Issue: 
Pages: 
130–3
Synopsis: 
A cross-sectional study in which DNA HLA typing methods were used to investigate the associations between HLA and class II alleles and the presence of systemic lupus erythematosus and antinuclear antibodies (ANA) in Jamaicans. The HLA associations with ANA were similar to those found in other ethnic groups, but no significant positive HLA association with SLE was found.

ABSTRACT

Objective: The relationship between human leukocyte antigens class II (HLA) and antinuclear antibodies
was investigated in Jamaican patients with Systemic Lupus Erythematosus (SLE).

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e-Published: 01 Jul, 2013

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