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Original Articles

The Skewness of Alpha Beta T-cell Receptors in Peripheral Blood of the Patients with Type 1 Diabetes

DOI: 
10.7727/wimj.2015.430
Synopsis: 
This paper focussed on the detection of TCR Vα and TCR Vβ skewness of patients with type 1 diabetes (T1D). In the results, we found that there were skewed genes in the TCR Vα and TCR Vβ. In our opinion, these skewed genes are probably relative to the onset of T1D.

 

ABSTRACT

 

Objective: To detect the skewness of TCR Vα and TCR Vβ of patients with Type 1 diabetes (T1D).

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Correlation Analysis and its Significance of Serum NT-proBNP, pH value and PaCO2 in Patients with Chronic Obstructive Pulmonary Disease

Issue: 
DOI: 
10.7727/wimj.2015.331
Pages: 
684–89
Synopsis: 
The regular detection of serum NT-proBNP, pH value and PaCO2 in chronic obstructive pulmonary disease (COPD) patients can detect disease progression early in COPD patients, which is conducive to the active treatment for COPD.

ABSTRACT 

Accepted: 
24 Aug, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 09 Mar, 2016

Protective Effect of Hydrogen Injected Subcutaneously on Testicular Tissues of Rats Exposed to Cigarette Smoke

DOI: 
10.7727/wimj.2015.332
Synopsis: 
Rat suffered smoke was used to investigate the protective effect of hydrogen injection on cigarette smoke-induced damage of reproductive system. Our result showed that hydrogen injected exerted protective effects on rats’ reproductive system exposed to smoke via inhibiting oxidative damage.

ABSTRACT

Objective: This study was aimed to investigate the protective effect of hydrogen on cigarette smoke-induced damage in rat reproductive system.

Methods: Adult male rats which suffered smoke were randomly divided into four groups, then total sperm count was counted, testosterone, superoxide dismutase (SOD), malondialdehyde (MDA) of serum and testis were determined. H&E straining of the testis tissues was also performed.

Accepted: 
24 Aug, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 09 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Evaluation of the Clinical and Laryngoscopic Findings in Patients with Angio-oedema: An 11-Year Experience at a Single Tertiary Care Centre

DOI: 
10.7727/wimj.2015.393
Synopsis: 
Angio-oedema Patients with dysphagia and swelling of posterior pharyngeal wall on clinical examination has significant positive correlation with laryngeal swelling on scopy; hence these patients should be referred to the otolaryngologist and to a facility with intensive care unit care as early as possible for safe management

ABSTRACT

 Objective: To evaluate the clinical features of angio-oedema (AE) and their correlation with fibre-optic nasolaryngoscopy (FNL) findings.

Methods:  The charts of adult AE patients for 225 episodes who were admitted as in-patients from January 2002 through December 2012 were reviewed.

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

A Cross-sectional Study to Assess the Knowledge and Attitude of the Private Dental Practitioners towards the Treatment of HIV/AIDS-Infected Individuals

Issue: 
DOI: 
10.7727/wimj.2015.391
Pages: 
559-64
Synopsis: 
This paper provides an insight into the level of the knowledge of private dental practitioners towards the dental treatment of the HIV patients. The study also emphasizes the key precautions to be followed during the dental treatment of HIV patients.

ABSTRACT

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

Neuromuscular Functional Changes of the Quadriceps after Anterior Cruciate Ligament Reconstruction

Issue: 
DOI: 
10.7727/wimj.2015.558
Pages: 
196-200
Synopsis: 
Neuromuscular changes of the quadriceps after anterior cruciate ligament reconstruction are significantly overcome in the first year after surgery. The electromyographic examinations indicated that tourniquet use not only caused functional harm in the quadriceps muscle, but it also caused structural damage.

ABSTRACT

Objective: To determine the factors related to quadriceps weakness, to evaluate electromyographic changes in the quadriceps and to attempt to determine the neuromuscular restoration period after anterior cruciate ligament (ACL) repair.

Accepted: 
07 Dec, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

Urinary Advanced Oxidation Protein Product: A Potential Oxidative Damage Marker for Cancer

Issue: 
DOI: 
10.7727/wimj.2012.324
Pages: 
505-10
Synopsis: 
The urinary oxidative protein damage in cancer is significantly higher than diabetes mellitus (with and without hypertension) and may potentially serve as a non-invasive oxidative biomarker for cancer.

ABSTRACT

Revised: 
03 Jun, 2015
Accepted: 
10 Aug, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

Weight, Sodium and Potassium Intake Perceptions among University Students in Barbados: Results from a Cardiovascular Health Perception Survey

Issue: 
DOI: 
10.7727/wimj.2015.396
Pages: 
641–47
Synopsis: 
The aim of this study is to evaluate dietary electrolyte intake and to discern the perceptions of cardiovascular health among a sample of undergraduates at the University of the West Indies, Cave Hill Campus.

ABSTRACT 

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 08 Mar, 2016

Prevalence of Sickle Cell Disease among Newborns in St Vincent and the Grenadines: A Retrospective Study

Issue: 
DOI: 
10.7727/wimj.2015.593
Pages: 
486–90
Synopsis: 
This is a retrospective study to determine the prevalence of sickle cell disease among lives births in St Vincent and the Grenadines. The results of this study indicate a birth prevalence that is similar to the published data from the other Caribbean Islands.

ABSTRACT

Objective: In the United States of America (USA), sickle cell disease (SCD) occurs in 1:375 African-American births. However, published data from the Caribbean have revealed higher numbers for some Caribbean islands. St Vincent and the Grenadines (SVG) is a multi-island nation in the Caribbean, and there are currently no data on the incidence or prevalence of the disease in this population. The objective of this study was to obtain birth prevalence estimates for SCD in SVG.

Accepted: 
07 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 08 Mar, 2016

Traditional Antiepileptics Remain First Line Treatment for Children with Epilepsy at The University Hospital of the West Indies, Kingston, Jamaica

DOI: 
10.7727/wimj.2015.473
Synopsis: 
Epilepsy in children at UHWI was reviewed in 63 children. No sex predilection was observed. Focal seizures were the most common overall. Carbamazepine was the drug of choice for treatment of focal seizures initially whilst valproic acid for generalized seizures.

ABSTRACT

Objectives: To describe the demography of epilepsy in children at the University Hospital of the West Indies and to review the frequency of major seizure types and antiepileptic drug therapy used at diagnosis.

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 08 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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