Original Articles

Protective Effect of Montelukast Sodium in Acute Ethyl Alcohol-induced Hepatic Injury in Rats

Issue:

Vol 69, Issue 5: 2021

DOI:

10.7727/wimj.2015.431

Pages:

345-9

Synopsis:

The aim of this study was to investigate the effect of montelukast sodium on acute hepatopathy induced by ethyl alcohol in rats. The liver tissue and biochemical parameters were assessed. Montelukast sodium administration had beneficial effects in alleviating ethyl-alcohol-induced hepatotoxicity.

ABSTRACT

Objective: Ethyl alcohol (EA) is a substance that is used commonly worldwide and known to have toxic effects on the liver. The aim of this study was to investigate the effect of montelukast sodium (MK) on acute hepatopathy induced by a single dose of EA in rats.

Received:

03 Aug, 2015

Accepted:

17 Nov, 2015

Published:

12 Nov, 2021

PDF Attachment:

wimj-iss5-2021_345_349.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 04 Mar, 2016

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In Vivo and in Vitro Pharmacological Evaluation of Gymnosporia Royleana

Issue:

Vol 68, Issue 2: 2019

DOI:

10.7727/wimj.2015.459

Pages:

121–28

Synopsis:

In the current investigation, we have made an effort to scientifically validate Gymnosporea royleana's traditional use in various pathological conditions such as antimicrobial, antidiabetic, antioxidant, anticancer and haemagglutination, which could be attributed to the phenolic content of the extract.

ABSTRACT

Received:

17 Aug, 2015

Revised:

10 Dec, 2015

Accepted:

04 Jan, 2016

Published:

17 Dec, 2019

PDF Attachment:

wimj-iss2-2019_121_128.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 02 Mar, 2016

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Are Patients Satisfied with their Total Joint Replacement Surgery? A Prospective Cross Sectional Survey

DOI:

10.7727/wimj.2015.380

Synopsis:

A prospective cross sectional study analyzed patients' satisfaction with arthroplasty in two independent groups. Statistically significant results showed increased function, decreased pain and improvement in the quality of life outcomes between the pre and postoperative groups. Clinically significant results indicated that the postoperative patients were satisfied with the peri-operative management and fulfilment of expectations following arthroplasty.

ABSTRACT

Objective: The number of patients requiring arthroplasty increases annually. Joint replacement surgery can improve a patient’s (QOL) quality of life. The effectiveness of this care from a patient’s own perspective assessed by patient reported outcome measures is just as important as the clinical measures. The aim of our study was to evaluate patients’ satisfaction following total joint replacement procedures.

Received:

06 Jul, 2015

Accepted:

10 Sep, 2015

PDF Attachment:

thomas_et_al-joint_feelings_shared_between_patients_and_surgeons.pdf

Journal Sections:

Original Articles

Keywords:

Surgery

Total Joint Replacement

Journal Authors:

e-Published: 01 Mar, 2016

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Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Comparison of Computed Tomography Pulmonary Angiograms at the University Hospital of the West Indies, Jamaica with Reported Cases in Literature

Issue:

Vol 68, Issue 2: 2019

DOI:

10.7727/wimj.2016.049

Pages:

160–64

Synopsis:

The yield of positive CTPAs at the UHWI is among the highest in the literature. There is no significant difference between the sexes in the mean age for and the yield of positive CTPAs.

ABSTRACT

Objective: This study was undertaken to determine the positive rate for computed tomography pulmonary angiograms (CTPAs) at the University Hospital of the West Indies (UHWI), to compare the positive rate at the UHWI to that reported in the literature and to compare the rates of positive CTPAs between the genders.

Received:

02 Feb, 2016

Accepted:

15 Feb, 2016

Published:

20 Dec, 2019

PDF Attachment:

wimj-iss2-2019_160_164.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 01 Mar, 2016

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The Living Kidney Donor Perspective in a Transplant Programme in Trinidad and Tobago – Seeing Donation through the Donor’s Eyes

Issue:

Vol 66, Issue 6: 2017

DOI:

10.7727/wimj.2016.037

Pages:

697–701

Synopsis:

Informed consent is critical to encourage and facilitate living donor renal transplants. Actual donors are the people best suited to identify the positives and the pitfalls of kidneys' donation. Kidney donors from June 2006 to March 2011 were surveyed.

ABSTRACT

Objectives: To determine issues from actual donors in our local programme which may have a psychological impact on kidney donation.

Methods: Living donors between June 2006 and March 2011 were given an un-standardized questionnaire. Of the 72 donors, 43 responded and information about their demographics, their motivation to donate and their transplant experiences were collated.

Received:

02 Feb, 2016

Accepted:

15 Feb, 2016

Published:

29 Dec, 2017

PDF Attachment:

wimj-iss6-2017_697_701.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 01 Mar, 2016

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TEOAE in Disorders of Ear Conduction Apparatus at Non-compensated and Compensated Pressure in Cavum Tympani

DOI:

10.7727/wimj.2016.043

Synopsis:

Pressure compensation in the middle ear has significantly affected obtaining transitory otoacoustic emissions (TEOAE) response and the size of this response. This treatment in the middle ear caused higher values of all TEOAE parameters in reference to emission parameters at ambiental pressure.

ABSTRACT

Objective: Transitory otoacoustic emissions (TEOAE) can be significant for diagnosing the hearing defect and for monitoring healing treatment for some diseases of ear conduction apparatus. They were investigated for non-compensated and compensated pressure in a middle ear in the two groups of diseases (inflammatory and non-inflammatory).

Received:

02 Feb, 2016

Accepted:

15 Feb, 2016

PDF Attachment:

karic_et_al-teoae_at_non-compensated_and_compensated_pressure.pdf

Journal Sections:

Original Articles

Keywords:

Inflammatory and non-inflammatory disease

middle ear

otoacoustic emissions

pressure compensation

Journal Authors:

e-Published: 01 Mar, 2016

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Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Saponin, Antioxidant and Free Radical Scavenging Properties of Blighia sapida Pods

DOI:

10.7727/wimj.2016.045

Synopsis:

The ackee is known to possess medicinal properties and is utilized in traditional medicine. This study was undertaken to evaluate the saponin, antioxidant and free radical scavenging properties of the ackee pods which are currently underutilized and discarded after processing.

ABSTRACT

Objective: To evaluate the saponin, antioxidant and free radical scavenging properties of Blighia sapida (ackee) pods. Saponins exhibit a wide range of medicinal properties which includes anticancer and anti-inflammatory activities.

Received:

02 Feb, 2016

Accepted:

15 Feb, 2016

PDF Attachment:

barnaby_and_williams-blighia_sapida_pod_extracts.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 01 Mar, 2016

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Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Cytotoxic T Lymphocyte-associated Antigen 4 Polymorphisms Correlated with Graves’ Disease in Patients of Han Ethnicity in Yunnan, China

Issue:

Vol 68, Issue 1: 2019

DOI:

10.7727/wimj.2016.026

Pages:

7-12

Synopsis:

This study aimed to investigate the correlations between polymorphisms at position 49 in exon 1 and position 318 in the promoter of the cytotoxic T lymphocyte-associated antigen 4 gene and autoimmune thyroid diseases in a Han Chinese population. This had not been reported before.

ABSTRACT

Objective: To investigate the correlations between polymorphisms at position 49 in exon 1 and position 318 in the promoter of the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene and autoimmune thyroid diseases in a Han Chinese population.

Received:

19 Jan, 2016

Accepted:

02 Feb, 2016

Published:

07 Oct, 2019

PDF Attachment:

wimj-iss1-2019_7_12.pdf

Journal Sections:

Original Articles

Keywords:

Autoimmune thyroid disease

cytotoxic T lymphocyte-associated antigen 4

Journal Authors:

e-Published: 01 Mar, 2016

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A Novel Marker Demonstrating Endothelial Dysfunction in Behçet's Disease, YKL-40

DOI:

10.7727/wimj.2016.025

Synopsis:

This study demonstrated that serum YKL-40 level was significantly higher in patients with an active and inactive Behçet's disease (BD) compared to the healthy individuals. This difference was, however, not the case between the active and inactive disease groups.

ABSTRACT

Background: To evaluate the relationship between disease activity and levels of YKL-40 in patients with Behcet’s disease (BD).

Methods: Twenty five active and twenty six inactive BD patients and 24 age and gender matched healthy control subjects were included in the study. Serum YKL-40 levels were measured using Enzyme Linked Immuno Sorbent Assay (ng/mL). Disease activity was assessed using Behcet’s Disease Current Activity Form (BDCAF).

Received:

19 Jan, 2016

Accepted:

02 Feb, 2016

PDF Attachment:

gunduz_et_al-bechets_disease.pdf

Journal Sections:

Original Articles

Keywords:

Endothelial dysfunction

Journal Authors:

e-Published: 01 Mar, 2016

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Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Meropenem Efflux in Pseudomonas aeruginosa at a Tertiary Care Hospital in Jamaica

Issue:

Vol 67, Issue 2: 2018

DOI:

10.7727/wimj.2016.022

Pages:

105-9

Synopsis:

This article examined efflux as a mechanism of carbapenem resistance in Pseudomonas aeruginosa isolates at a hospital in Jamaica. The study detected that 80% of the isolates tested had efflux as a mechanism of resistance to meropenem.

ABSTRACT

Objective: Several mechanisms account for carbapenem resistance in Pseudomonas (P.) aeruginosa which is an emerging problem at a tertiary care hospital (TCH) in Jamaica. The observed pattern of carbapenem resistance that results from efflux mechanisms is unique because it is specific to meropenem (MEM). Investigation of efflux as a mechanism of carbapenem resistance needed to be done as the information obtained could inform therapeutic and infection control strategies.

Received:

13 Jan, 2016

Accepted:

21 Jan, 2016

Published:

03 Jun, 2018

PDF Attachment:

wimj-iss2-2018_105_109.pdf

Journal Sections:

Original Articles

Keywords:

resistance