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Original Articles

Investigation of Paraoxanase Enzyme Polymorphism in Patients with Alopecia Areata

DOI: 
10.7727/wimj.2015.491
Synopsis: 
We investigated the relationship between alopecia areata (AA) and polymorphisms of paraoxanase 1 (PON1). Although the frequency of PON 55 L allel was higher in the patient group than control, there was no relation between the AA and both PON1 M/L55 and R/Q192 polymorphism.

ABSTRACT

Objective: In this study, we investigated the relationship between AA and genetic polymorphisms of PON1 R192Q and PON1 L55M.

Methods: One hundred and nineteen patients with AA and 104 healthy controls were included in this study. The changes in aminoacid squencies on codon 55 and 192 were analysed by the polymerase chain reaction and restriction enzymes.

Received: 
07 Sep, 2015
Accepted: 
30 Sep, 2015
PDF Attachment: 
PDF icon gurel_et_al-investigation_of_paraoxanase_enzyme_polymorphism_in_patients_with_alopecia_areata_text.pdf
Journal Sections: 
Original Articles
Keywords: 
polymorphism
Alopecia areata
paraoxonase-1
Journal Authors: 
A Gurel
F Tülübaş
M Kulaç
H Erdogan
B Topçu
G Kalkan
H Özyurt
e-Published: 15 Mar, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

The Place of Atopy in the Aetiology of Acute Appendicitis in Children

DOI: 
10.7725/wimj.2015.005
Synopsis: 
The etiology of appendicitis is multifactorial, although it is affected by several precursor factors. While there are several known factors in acute appendicitis, the cause cannot be identified in some cases. The purpose of this study was to investigate whether allergic diseases cause a disposition to appendicitis

ABSTRACT

Objective: Appendicitis, the most common cause of abdominal pain requiring surgery in children, refers to inflammation of the vermiform appendix. The etiology of appendicitis is multifactorial, although it is affected by several precursor factors. The purpose of this study was to investigate whether allergic diseases cause a disposition to appendicitis.

Received: 
20 Jan, 2015
Accepted: 
30 Jun, 2015
PDF Attachment: 
PDF icon cevizci_et_al-atopy_and_acute_appendicitis.pdf
Journal Sections: 
Original Articles
Keywords: 
Child
Acute Appendicitis
atopy
Journal Authors: 
MN Cevizci
A Söğüt
A Çayir
M Demir
SA Ozman
F Erdoğan
e-Published: 15 Mar, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Thyroid Hormone Levels in Chronic Schizophrenic Patients: Association with Psychopathology

Issue: 
Vol 65, Issue 2: 2016
DOI: 
10.7727/wimj.2015.186
Pages: 
312-5
Synopsis: 
The aim of this study was to investigate the changes in thyroid hormone levels in patients with chronic schizophrenia. The level of FT4 in the schizophrenia group statistically significant was lower than the control group.

ABSTRACT

Objectives: Thyroid disorders are highly prevalent in patients with schizophrenia. Changes in the levels of thyroid hormones cause the occurrence of psychiatric disorders and affect the response to treatment. The aim of this study was to investigate the changes in thyroid hormone levels in patients with chronic schizophrenia, and to demonstrate any association between psychiatric symptoms with hormones.

Received: 
15 Apr, 2015
Accepted: 
30 Jun, 2015
PDF Attachment: 
PDF icon wimj_iss2_2016_312-15.pdf
Journal Sections: 
Original Articles
Keywords: 
schizophrenia
Neuroleptics drugs
thyroid hormones
Journal Authors: 
S Telo
S Bilgic
N Karabulut
e-Published: 15 Mar, 2016

Phototherapy Induces an Improvement in Clinical and Biochemical Scores in Patients with Rheumatoid Arthritis

Issue: 
Vol 69, Issue 1: 2021
DOI: 
10.7727/wimj.2015.490
Pages: 
21-5
Synopsis: 
Rheumatoid arthritis is a common autoimmune disease for which there is no known cure. Within a range of 425–650 nm and 11.33 J/cm2, phototherapy can induce an improvement in clinical and laboratorial variables in patients with rheumatoid arthritis.

ABSTRACT

Objective: Rheumatoid arthritis (RA) is a common autoimmune disease for which there is no known cure. Ultraviolet light can induce immunosuppressive effects. Our main objective was to ascertain whether a complementary treatment with phototherapy would improve changes in functional scales in patients with RA.

Methods: Seven women with RA were enrolled for this study and submitted to phototherapy sessions with a 425–650 nm lamp.

Received: 
07 Sep, 2015
Accepted: 
30 Sep, 2015
Published: 
30 Apr, 2021
PDF Attachment: 
PDF icon wimj-iss1-2021_21_25.pdf
Journal Sections: 
Original Articles
Keywords: 
C-reactive protein
functional scales
phototherapy
Rheumatoid Arthritis
Journal Authors: 
J Meneses Calderón
G Aburto Huacuz
I González Sánchez
A Gutiérrez Vilchis
H Mendieta Zerón
e-Published: 15 Mar, 2016

Protective Effect of Wolfberry Extract on Acetic Acid-induced Colitis in Rats

Issue: 
Vol 69, Issue 5: 2021
DOI: 
10.7727/wimj.2015.444
Pages: 
356-61
Synopsis: 
Wolf berry extract has certain anti-ageing, neuroprotective, anti-fatigue/endurance-increasing, and anti-oxidant biological effects with antitumour activity and cytoprotection. The protective effect of Wolf berry against acetic-acid-induced colitis in rats and Wolf berry extract effectiveness were investigated in this study.

ABSTRACT

Objective: To investigate the protective effect of wolfberry (WB) against acetic acid-induced colitis in rats.

Received: 
17 Aug, 2015
Accepted: 
28 Sep, 2015
Published: 
12 Nov, 2021
PDF Attachment: 
PDF icon wimj-iss5-2021_356_361.pdf
Journal Sections: 
Original Articles
Keywords: 
Acute colitis
antioxidant
wolfberry.
Journal Authors: 
M İcer
E Gunduz
Y Zengin
R Dursun
HM Durgun
U Alabalık
İ Kaplan
C Guloglu
e-Published: 15 Mar, 2016

Prospective Survey of Lower Urinary Tract Symptom and the Commonest Risk Factor among Urological Patients in Nigeria

DOI: 
10.7727/wimj.2015.434
Synopsis: 
Lower urinary tract symptoms (LUTS) is a conglomeration of symptoms characterizing the process of evacuating urine from the bladder. Apart from age, other risk factors commonly associated with an increased risk of LUTS are obesity, smoking, alcohol consumption and elevated blood pressure. The highest prevalence of LUTS was at the 7th decade of life and alcohol consumption was the commonest risk factor in south west, Nigeria. Majority of the patients presented with moderate to severe symptoms.

ABSTRACT

Objective: To determine the age-specific prevalence, severity of LUTS and the commonest risk factor among Nigerian patients.

Received: 
03 Aug, 2015
Accepted: 
25 Nov, 2015
PDF Attachment: 
PDF icon adegun-survey_of_luts_and_risk_factors_in_nigeria.pdf
Journal Sections: 
Original Articles
Keywords: 
Alcohol
Age
lower urinary tract symptom
Journal Authors: 
PA Temi
e-Published: 15 Mar, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Predictive Utility of Anthropometric Based Cut-offs in Assessing Excess Adiposity among Preschool Children in a Multiethnic Population

Issue: 
Vol 69, Issue 2: 2021
DOI: 
10.7727/wimj.2015.485
Pages: 
114-20
Synopsis: 
We evaluated the diagnostic performance of various recommended anthropometric-based cut-offs in identifying excess adiposity in a multi-ethnic, pre-school population. Our results suggested that diagnostic performance was associated with gender and the cut-offs used, but was not associated with ethnicity.

ABSTRACT

Objective: Screening for childhood obesity is a necessary step in developing appropriate and effective interventions. We evaluated the diagnostic performance of various recommended international anthropometric cut-offs based on body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), triceps skinfold (TSF), and mid-upper arm circumference (MUAC) in predicting excess adiposity (body fat ≥ 25%) in a random sample of Trinidadian preschoolers.

Received: 
07 Sep, 2015
Accepted: 
30 Sep, 2015
Published: 
22 Jun, 2021
PDF Attachment: 
PDF icon wimj-iss2-2021_114_120.pdf
Journal Sections: 
Original Articles
Keywords: 
Cut-offs
Diagnostics
obesity
preschooler
Journal Authors: 
A Ramcharitar-Bourne
SD Nichols
N Badrie
e-Published: 15 Mar, 2016

Evaluative Research on Pharmacist-managed Diabetes Care: Focus on Self-monitoring of Blood Glucose

Issue: 
Vol 68, Issue 2: 2019
DOI: 
10.7727/wimj.2015.529
Pages: 
101–107
Synopsis: 
This pharmacist evaluative research study (PHARMERS) sought to empower pharmacists to assist in the management of poorly-controlled, diabetic patients. We hoped to demonstrate that patients stand a better chance of achieving improved glycaemic control if closely monitored by a pharmacist.

Abstract

Objective: Pharmacists have not demonstrated the ability to manage chronic diseases such as Type 2 Diabetes Mellitus, which is an ongoing problem in Trinidad and Tobago. The primary objective was to demonstrate that pharmacists can assist patients to achieve at least a 1% decrease in glycosylated haemoglobin (HbA1c ).

Received: 
02 Nov, 2015
Accepted: 
17 Nov, 2015
Published: 
10 Dec, 2019
PDF Attachment: 
PDF icon wimj-iss2-2019_101_107.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
Chronic diseases
glycosylated haemoglobin
managed care
pharmaceutical care
pharmacists
Journal Authors: 
PI Sealy
DN Ignacio
G Legall
e-Published: 15 Mar, 2016

Plasma Kisspeptin Levels in Hypothyroidism and Premature Newborns

Issue: 
Vol 65, Issue 3: 2016
DOI: 
10.7727/wimj.2015.287
Pages: 
525-28
Synopsis: 
Kisspeptin may play a role clarification in the newborn period of various changes. A statistically significant kisspeptin levels was determined between hypothyroid and the control groups and also a statistically significant kisspeptin levels was seen between the premature and control groups.

ABSTRACT

Aim: The purpose of this study was to determine kisspeptin levels in healthy newborns and to show whether there is significant difference kisspeptin levels between males and females in hypothyroid newborns and healthy term newborns.

Received: 
03 Jun, 2015
Accepted: 
30 Jun, 2015
PDF Attachment: 
PDF icon wimj_iss3_2016_525_528.pdf
Journal Sections: 
Original Articles
Keywords: 
hypothyroidism
Newborn
kisspeptin
premature
Journal Authors: 
A Kaya
Z Orbak
H Polat
E Şebin
İ Polat
E Gülfidan
e-Published: 15 Mar, 2016

Relationship Between ABO Blood Group and the Incidence of Gestational Diabetes in Pregnant Women ‎in Gorgan, North of Iran‎

DOI: 
10.7727/wimj.2015.257
Synopsis: 
So far, the relationships between blood groups and 70 diseases had been established. Therefore, the present study was conducted, for the determination of the relationship between ABO blood groups with GDM. The findings showed that blood group O had preventive effects on the development of GDM and subjects with non O blood group were more likely to suffer from GDM.

ABSTRACT

INTRODUCTION: Gestational diabetes mellitus (GDM) is defined as a glucose intolerance that first occurs during pregnancy (1). ABO blood group has an important role in the human body Physiology.Early detection and treatment of GDM reduce its complications  (3).So far, the relationship between blood group and 70 disease has been identified.Therefore, the present study were conducted,for determination  the relationship between ABO blood groups with GDM.

Received: 
21 May, 2015
Accepted: 
23 Nov, 2015
PDF Attachment: 
PDF icon mohammadzade20et20al-relationship20between2020blood20group20and20gestational20diabetes1.pdf
Journal Sections: 
Original Articles
Keywords: 
ABO blood group
gestational diabetes
incidence
Journal Authors: 
F Mohammadzade
F Maryam
S Alireza
V Mohammadali
e-Published: 14 Mar, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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