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Original Articles

The Effects of Low-dose Bisoprolol on the Renin-Angiotensin-Aldosterone System and Ventricular Remodelling

Issue: 
DOI: 
10.7727/wimj.2016.260
Pages: 
629-32
Synopsis: 
This research is aimed to explore the effects of low-dose bisoprolol on the renin-angiotensin-aldosterone system (RAAS) and ventricular remodelling and found that Bisoprolol can inhibit the RAAS and reverse ventricular remodelling.

ABSTRACT


Objective: To explore the effects of low-dose bisoprolol on the renin-angiotensin-aldosterone system (RAAS) and ventricular remodelling.

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 09 Jul, 2018

Randomized Controlled Trial between Conventional Fractionation Radiotherapy and Accelerated Hyperfractionation Radiotherapy in the Elderly with Locally Advanced Non-small Cell Lung Carcinoma

Issue: 
DOI: 
10.7727/wimj.2016.259
Pages: 
623-8
Synopsis: 
This study showed that compared with conventional fractionation radiotherapy in non-small cell lung carcinoma, accelerated hyperfractionation radiotherapy showed better short-term decentralized control effect.

ABSTRACT

Objective: This study aimed at observing and discussing the curative effect of conventional fractionation radiotherapy and accelerated hyperfractionation radiotherapy in the elderly
with locally advanced non-small cell lung carcinoma (NSCLC).

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 09 Jul, 2018

Osteoarthritis Patients’ Synovium IL-7R Expression and Value Research of Its Clinical Diagnosis

Issue: 
DOI: 
10.7727/wimj.2016.250
Pages: 
613-7
Synopsis: 
This study discussed the expression of IL-7R genes of patients with osteoarthrosis and the value of its clinical significance. It found that IL-7R expression existed both in the normal synovial tissues in the knees and synovial tissues in patients with osteoarthrosis but the latter was lower.

 ABSTRACT

Objective: To discuss the expression of IL-7R genes in the synovium of osteoarthritis (OA) patients and the value of its clinical significance.

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 09 Jul, 2018

Cervical Cancer Hela Cell Osteopontin Gene Suppression Model and Detection

Issue: 
DOI: 
10.7727/wimj.2016.254
Pages: 
608-12
Synopsis: 
This research is to develop an osteopontin (OPN) specific siRNA expression vector and transfect it into cervical cancer Hela cells, in order to obtain OPN stable transfection cell lines, thus providing support for further study on the mechanism of OPN in cervical cancer Hela cells.

ABSTRACT


Objective: To build an osteopontin (OPN) specific short interfering ribonucleic acid (siRNA) expression vector and transfect it into cervical cancer Hela cells, in order to obtain OPN stable transfection cell lines, thus providing support to the further study on the mechanism of OPN in cervical cancer Hela cells.

Accepted: 
22 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 09 Jul, 2018

Effects of Continuous Positive Airway Pressure Ventilation on Serum Cystatin C and Leptin Concentration Levels in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

DOI: 
10.7727/wimj.2017.138
Pages: 
Synopsis: 
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a sleep-related respiratory disorder that increases the risk of several other diseases. We evaluated the mode of action of continuous positive airway pressure (CPAP), which is the treatment of choice, in OSAHS therapy. The results of this study reveal that CPAP acts by reducing the levels of cystatin C and leptin in the serum which are involved in raising the basal metabolic rate in OSAHS.

ABSTRACT

Objective: To evaluate the effects of continuous positive airway pressure (CPAP) on serum cystatin C and leptin concentration levels in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).

Accepted: 
12 Dec, 2017
Journal Sections: 
Journal Authors: 
e-Published: 23 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Correlation between Processus vaginalis Patency and Metachronous Inguinal Hernia in Children

DOI: 
10.7727/wimj.2016.595
Pages: 
Synopsis: 
The incidence of asymptomatic patent processus vaginalis (PPV) does not significantly decrease with age. However, age and gender play an important role in the development of MCIH from PPV.

ABSTRACT

Purpose: In the present study, we report the incidence of CPPV with unilateral inguinal hernia and future MCIH, with the aim of assisting treatment of this disease.

Methods: A total of 20 636 cases of unilateral inguinal hernia that were surgically treated between January 2002 and December 2009 were retrospectively evaluated. Statistics were performed using Pearson test or χ2 as appropriate, and p < 0.05 was considered statistically significant.

Accepted: 
15 Jan, 2017
Journal Sections: 
e-Published: 23 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Diabetic Hyperglycaemia Protects Smooth Muscle Arterial Cells but Not Macrophages and Endothelial Cells from the Cytotoxic Effects of 7-Ketocholesterol: An In Vitro Study

Issue: 
DOI: 
10.7727/wimj.2016.499
Pages: 
483-7
Synopsis: 
In the study reported, macrophages, smooth muscle and endothelial arterial cells were challenged against different concentrations of 7-ketocholesterol in normoglycemic and high glucose conditions. The hyperglycaemic medium protects only smooth muscle artery cells against the cytotoxic effects of 7-ketocholesterol.

ABSTRACT

Accepted: 
18 Dec, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 23 Jan, 2018

A 30 Year Review of Paediatric Central Nervous System Malignancies in Jamaica: 1978–2007

DOI: 
10.7727/wimj.2017.165
Pages: 
Synopsis: 
The epidemiologic profile of paediatric Central Nervous System (CNS) malignancies in Jamaica shows an overall female preponderance in marked contrast to worldwide data which shows a male preponderance. Of all the subtypes, the embryonal tumours showed the most striking female preponderance.

ABSTRACT

Objective: To describe the epidemiologic features of malignant central nervous system (CNS) neoplasms in Jamaican children.

Accepted: 
12 Dec, 2017
Journal Sections: 
e-Published: 18 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Brain MRI Findings and Distribution of the Findings According to the Age Groups in Childhood Epilepsies

DOI: 
10.7727/wimj.2017.175
Pages: 
Synopsis: 
The most common pathology in all age groups that caused epilepsy in children was the indication of parenchymal damage. Another common pathology is hippocampal sclerosis and cortical developmental abnormalities. MRI is a noninvasive imaging modality that can be used to identify pathologies that do not involve any ionizing radiation and lead to epileptic attacks in childhood.

ABSTRACT

Objective: We aimed to retrospectively analyze the magnetic resonance imaging (MRI) observations and the distribution of etiological factors according to age groups in cases with MRI examinations for an epilepsy diagnosis.

Methods: The brain MRI of 606 cases from the 0–17 years age group were analyzed retrospectively, and the findings were evaluated according to the age group. 

Accepted: 
12 Dec, 2017
Journal Sections: 
e-Published: 18 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

An Investigation of Serum Magnesium and Red Blood Cell Distribution Width Values in Patients with Obstructive Sleep Apnea Syndrome

DOI: 
10.7727/wimj.2017.153
Synopsis: 
The study investigated the serum levels of magnesium and red blood cell distribution width (RDW) values and their relationship with polysomnographic parameters in patients with OSAS. Serum RDW values were significantly elevated and magnesium levels were significantly decreased in OSAS. Also, RDW was positively and magnesium was negatively correlated with polysomnographic parameters. To our knowledge, this was the first study investigating the association between RDW and Mg levels in the same patient population.

ABSTRACT

Objective: Obstructive Sleep Apnea Syndrome (OSAS) leads to complications in several systems. The purpose of this study was to examine serum magnesium and red cell distribution width (RDW) values in OSAS, a chronic inflammation, and thus to reveal the relations between these two parameters and with other sleep parameters.

Accepted: 
20 Dec, 2017
Journal Sections: 
e-Published: 22 Dec, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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