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Original Articles

Randomized Controlled Trial between Conventional Fractionation Radiotherapy and Accelerated Hyperfractionation Radiotherapy in the Elderly with Locally Advanced Non-small Cell Lung Carcinoma

Issue: 
Vol 65, Issue 4: 2016 – Health Science
DOI: 
10.7727/wimj.2016.259
Pages: 
623-8
Synopsis: 
This study showed that compared with conventional fractionation radiotherapy in non-small cell lung carcinoma, accelerated hyperfractionation radiotherapy showed better short-term decentralized control effect.

ABSTRACT

Objective: This study aimed at observing and discussing the curative effect of conventional fractionation radiotherapy and accelerated hyperfractionation radiotherapy in the elderly
with locally advanced non-small cell lung carcinoma (NSCLC).

Received: 
07 Jun, 2016
Accepted: 
22 Aug, 2016
Published: 
09 Jul, 2018
PDF Attachment: 
PDF icon wimj-iss4-2016_623_628.pdf
Journal Sections: 
Original Articles
Keywords: 
Accelerated hyperfractionation radiotherapy
conventional fractionation radiotherapy
the elderly
phase III non-small cell lung carcinoma
short-term effects
Journal Authors: 
YY Wu
FY Li
XJ You
YB Wang
JH Wang
YC Lin
LL Wu
e-Published: 09 Jul, 2018

Osteoarthritis Patients’ Synovium IL-7R Expression and Value Research of Its Clinical Diagnosis

Issue: 
Vol 65, Issue 4: 2016 – Health Science
DOI: 
10.7727/wimj.2016.250
Pages: 
613-7
Synopsis: 
This study discussed the expression of IL-7R genes of patients with osteoarthrosis and the value of its clinical significance. It found that IL-7R expression existed both in the normal synovial tissues in the knees and synovial tissues in patients with osteoarthrosis but the latter was lower.

 ABSTRACT

Objective: To discuss the expression of IL-7R genes in the synovium of osteoarthritis (OA) patients and the value of its clinical significance.

Received: 
07 Jun, 2016
Accepted: 
22 Aug, 2016
Published: 
09 Jul, 2018
PDF Attachment: 
PDF icon wimj-iss4-2016_613_617.pdf
Journal Sections: 
Original Articles
Keywords: 
IL-7R expression
osteoarthritis
real-time quantitative polymerase chain reaction
Journal Authors: 
ZL Sun
WQ Yang
XJ Guo
HJ Wu
DF Zhang
e-Published: 09 Jul, 2018

Cervical Cancer Hela Cell Osteopontin Gene Suppression Model and Detection

Issue: 
Vol 65, Issue 4: 2016 – Health Science
DOI: 
10.7727/wimj.2016.254
Pages: 
608-12
Synopsis: 
This research is to develop an osteopontin (OPN) specific siRNA expression vector and transfect it into cervical cancer Hela cells, in order to obtain OPN stable transfection cell lines, thus providing support for further study on the mechanism of OPN in cervical cancer Hela cells.

ABSTRACT


Objective: To build an osteopontin (OPN) specific short interfering ribonucleic acid (siRNA) expression vector and transfect it into cervical cancer Hela cells, in order to obtain OPN stable transfection cell lines, thus providing support to the further study on the mechanism of OPN in cervical cancer Hela cells.

Received: 
07 Jun, 2016
Accepted: 
22 Aug, 2016
Published: 
09 Jul, 2018
PDF Attachment: 
PDF icon wimj-iss4-2016_608_612.pdf
Journal Sections: 
Original Articles
Keywords: 
Cervical cancer
osteopontin
ribonucleic acid interference
Journal Authors: 
SH Xiao
JW Ying
TW Ying
W Xue
YW Li
e-Published: 09 Jul, 2018

Effects of Continuous Positive Airway Pressure Ventilation on Serum Cystatin C and Leptin Concentration Levels in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

DOI: 
10.7727/wimj.2017.138
Pages: 
Synopsis: 
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a sleep-related respiratory disorder that increases the risk of several other diseases. We evaluated the mode of action of continuous positive airway pressure (CPAP), which is the treatment of choice, in OSAHS therapy. The results of this study reveal that CPAP acts by reducing the levels of cystatin C and leptin in the serum which are involved in raising the basal metabolic rate in OSAHS.

ABSTRACT

Objective: To evaluate the effects of continuous positive airway pressure (CPAP) on serum cystatin C and leptin concentration levels in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).

Received: 
12 Jul, 2017
Accepted: 
12 Dec, 2017
Journal Sections: 
Original Articles
Keywords: 
Continuous positive airway pressure (CPAP)
Leptin
obstructive sleep apnea hypopnea syndrome (OSAHS)
serum cystatin C
Journal Authors: 
F Li
J Han
L Kang
J Fei
Z Song
e-Published: 23 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Correlation between Processus vaginalis Patency and Metachronous Inguinal Hernia in Children

DOI: 
10.7727/wimj.2016.595
Pages: 
Synopsis: 
The incidence of asymptomatic patent processus vaginalis (PPV) does not significantly decrease with age. However, age and gender play an important role in the development of MCIH from PPV.

ABSTRACT

Purpose: In the present study, we report the incidence of CPPV with unilateral inguinal hernia and future MCIH, with the aim of assisting treatment of this disease.

Methods: A total of 20 636 cases of unilateral inguinal hernia that were surgically treated between January 2002 and December 2009 were retrospectively evaluated. Statistics were performed using Pearson test or χ2 as appropriate, and p < 0.05 was considered statistically significant.

Received: 
15 Dec, 2016
Accepted: 
15 Jan, 2017
Journal Sections: 
Original Articles
Keywords: 
children
inguinal hernia
laparoscopy
metachronous hernia
patent processus vaginalis (PPV)
Journal Authors: 
Y Xue-qiang
Z Nan-nan
Y Jun
D Xu-fei
B Hong-qiang
S Xuan
e-Published: 23 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Diabetic Hyperglycaemia Protects Smooth Muscle Arterial Cells but Not Macrophages and Endothelial Cells from the Cytotoxic Effects of 7-Ketocholesterol: An In Vitro Study

Issue: 
Vol 69, Issue 7: 2022
DOI: 
10.7727/wimj.2016.499
Pages: 
483-7
Synopsis: 
In the study reported, macrophages, smooth muscle and endothelial arterial cells were challenged against different concentrations of 7-ketocholesterol in normoglycemic and high glucose conditions. The hyperglycaemic medium protects only smooth muscle artery cells against the cytotoxic effects of 7-ketocholesterol.

ABSTRACT

Received: 
06 Oct, 2016
Accepted: 
18 Dec, 2017
Published: 
02 May, 2022
PDF Attachment: 
PDF icon wimj-iss7-2022_483_487.pdf
Journal Sections: 
Original Articles
Keywords: 
Atherosclerosis
hyperglycaemia
7-Ketocholesterol
Journal Authors: 
JC Erustes
CRS Carneiro
GM Favero
e-Published: 23 Jan, 2018

A 30 Year Review of Paediatric Central Nervous System Malignancies in Jamaica: 1978–2007

DOI: 
10.7727/wimj.2017.165
Pages: 
Synopsis: 
The epidemiologic profile of paediatric Central Nervous System (CNS) malignancies in Jamaica shows an overall female preponderance in marked contrast to worldwide data which shows a male preponderance. Of all the subtypes, the embryonal tumours showed the most striking female preponderance.

ABSTRACT

Objective: To describe the epidemiologic features of malignant central nervous system (CNS) neoplasms in Jamaican children.

Received: 
01 Sep, 2017
Accepted: 
12 Dec, 2017
Journal Sections: 
Original Articles
Keywords: 
central nervous system
Malignancy
paediatric
Journal Authors: 
KEG Blake
J Jaggon
K Bishop
B Hanchard
T Gibson
N Waugh
D McNaughton
G Char
e-Published: 18 Jan, 2018

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Brain Magnetic Resonance Imaging Findings and Distribution of the Findings According to the Age Groups in Childhood Epilepsies

Issue: 
Vol 71, Issue 1: 2024
DOI: 
10.7727/wimj.2017.175
Pages: 
63-8
Synopsis: 
This study showed that the most common pathology that caused epilepsy in children was the indication of parenchymal damage. Another common pathology is hippocampal sclerosis and cortical developmental abnormalities. MRI is a non-invasive imaging modality that that does not involve any ionizing radiation and can be used to identify pathologies that lead to epileptic attacks in childhood.

ABSTRACT

Objective: To retrospectively analyse the magnetic resonance imaging (MRI) observations and the distribution of etiological factors according to age groups in cases with MRI examinations for an epilepsy diagnosis.

Methods: The brain MRI of 606 cases from the 0–17 years age group were analysed retrospectively, and the findings were evaluated according to the age group.

Received: 
11 Sep, 2017
Accepted: 
12 Dec, 2017
Published: 
30 Mar, 2024
PDF Attachment: 
PDF icon wimj-iss1-2024_63_68.pdf
Journal Sections: 
Original Articles
Keywords: 
children
epilepsy
magnetic resonance imaging.
Journal Authors: 
SK Balık
M Öztürk
C Göya
F Ekici
e-Published: 18 Jan, 2018

An Investigation of Serum Magnesium and Red Blood Cell Distribution Width Values in Patients with Obstructive Sleep Apnoea Syndrome

Issue: 
Vol 71, Issue 1: 2024
DOI: 
10.7727/wimj.2017.153
Pages: 
58-62
Synopsis: 
The study investigated the serum levels of magnesium and red blood cell distribution width (RDW) values and their relationship with polysomnographic parameters in patients with Obstructive sleep apnoea syndrome (OSAS). Serum RDW values were significantly elevated and magnesium levels were significantly decreased in OSAS. Also, RDW was positively and magnesium was negatively correlated with polysomnographic parameters. To our knowledge, this was the first study investigating the association between RDW and Mg levels in the same patient population.

ABSTRACT

Objective: Obstructive sleep apnoea syndrome (OSAS) leads to complications in several systems. The purpose of this study was to examine serum magnesium and red cell distribution width (RDW) values in OSAS, a chronic inflammation, and thus to reveal the relations between these two parameters and with other sleep parameters.

Received: 
25 Jul, 2017
Accepted: 
20 Dec, 2017
Published: 
30 Mar, 2024
PDF Attachment: 
PDF icon wimj-iss1-2024_58_62.pdf
Journal Sections: 
Original Articles
Keywords: 
Inflammation
magnesium
obstructive sleep apnoea syndrome
red blood cell distribution width.
Journal Authors: 
K Kilic
MS Sakat
O Araz
MS Gozeler
e-Published: 22 Dec, 2017

Age, Body Mass and Physical Activity Determinants of Facial Acne Severity among Southern Nigerian Adolescents and Young Adults

DOI: 
10.7727/wimj.2017.162
Synopsis: 
The study explored the relationship between facial acne severity, age of patients, body mass and physical activity indexes. Acne severity has a significant relationship with age of patients but not body mass or physical activity indexes.

ABSTRACT

Objective: To explore the relationship between severity of acne with Age, Body Mass Index (BMI) and Physical Activity Index (PAI) of the patients.

Received: 
31 Aug, 2017
Accepted: 
20 Dec, 2017
Journal Sections: 
Original Articles
Keywords: 
Acne vulgaris
Adolescent
body mass index
physical activity index
young adult
Journal Authors: 
CC Anyachukwu
OKK Onyeso
CI Ezema
e-Published: 22 Dec, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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