Original Articles

Updates on Current Advances in Gene Therapy

Issue:

Vol 60, issue 2 (2011)

Pages:

188–94

Synopsis:

Gene therapy is the attempt to treat diseases by means of genetic manipulation. Numerous challenges remain to be overcome before it becomes available as a safe and effective treatment option. This article discusses the commonly used techniques employed in gene therapy, and summarizes breakthroughs achieved so far in clinical applications of gene therapy.

ABSTRACT

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e-Published: 17 Oct, 2013

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Subjective Well-being of Adults with Homozygous Sickle Cell Disease in Jamaica

Issue:

Vol 60, issue 2 (2011)

Pages:

181–7

Synopsis:

Advances in treatment of sickle cell disease have improved the prognosis for patients. As these patients are living longer, issues of subjective well-being become important. Past studies have mostly focussed on patients’ negative life experiences. This study examines both patients’ positive and negative experiences, as well as their satisfaction with life.

ABSTRACT

Objectives: This study compared the subjective well-being of adults with homozygous sickle cell (SS) disease to a matched group of healthy adult peers. The differential influence of sociodemographic factors on the subjective well-being of Sickle Cell patients was also examined.

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Keywords:

subjective well-being

quality of life.

Journal Authors:

JA Thomas

GE Lipps

e-Published: 17 Oct, 2013

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Compliance with Intramuscular Penicillin Prophylaxis in Children with Sickle Cell Disease in Jamaica

Issue:

Vol 60, issue 2 (2011)

Pages:

177–80

Synopsis:

Intramuscular penicillin prophylaxis, despite commonly perceived challenges, is a practical option which can contribute to better patient compliance and thus significantly impact global rates of invasive pneumococcal disease and its complications in children with SCD and other similar conditions.

ABSTRACT

Objective: Penicillin prophylaxis is important in the defence against invasive pneumococcal disease in sickle cell disease (SCD). Penicillin may be administered by the oral route or by the intramuscular (IM) route. Compliance with the oral route, although difficult to assess, has been reported to be highly variable and often poor. We sought to determine the compliance rate with intramuscular penicillin (IM) prophylaxis in children with sickle cell disease.

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Original Articles

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Compliance

intramuscular

penicillin prophylaxis

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e-Published: 17 Oct, 2013

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Temporomandibular Joint Ankylosis in a Nigerian Teaching Hospital

Issue:

Vol 60, issue 2 (2011)

Pages:

172–6

Synopsis:

A retrospective study of temporomandibular joint ankylosis in a Nigerian Teaching Hospital is presented. There were 33 ankylosis from 26 patients (12 males and 14 females). The anaesthetic and surgical challenges in a resource poor environment are discussed.

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Temporomandibular Joint

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The Jamaican Adolescent’s Perspective on Violence and its Effects

Issue:

Vol 60, issue 2 (2011)

Pages:

165–71

Synopsis:

A qualitative study of rural and urban based Jamaican adolescents’ perspectives on violence, its impact on their attitudes and behaviours as well as their implications.

ABSTRACT

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Original Articles

Keywords:

Adolescents

emotional intelligence

violent environment

reslience

Journal Authors:

A Bailey

e-Published: 17 Oct, 2013

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Are Parents in Tune with Music Their Adolescent Children Enjoy? Are There Missed Opportunities for Sexual and Reproductive Health Dialogue?

Issue:

Vol 60, issue 2 (2011)

Pages:

158–64

Synopsis:

Adolescents listen to and learn sexual and reproductive health themes from dancehall music whether or not parents have reservations to them doing so. These may subsequently influence sexual and reproductive health behaviour. Dancehall music provides opportunities for parents to initiate discussion of values pertaining to sexual and reproductive health.

ABSTRACT

The perspectives of adolescents were solicited on the issue of sexual and reproductive health messages they received through dancehall music as well as their perceptions of parents’ views of such messages and adolescents’ indulgence with this genre of music.

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The Outcome of Febrile Neutropenic Episodes in Paediatric Oncology at the Wendy Fitzwilliam Paediatric Hospital

Issue:

Vol 60, issue 2 (2011)

Pages:

153–7

Synopsis:

This study aimed to determine the outcome of the febrile neutropenic episodes in the paediatric oncology population at one centre in Trinidad. A positive treatment outcome was achieved in 91% of the episodes.

ABSTRACT

Objective: To evaluate the incidence, presentation, treatment and outcome of febrile neutropenic episodes of patients treated at the Wendy Fitzwilliam Paediatric Hospital (WFPH) in Trinidad and Tobago.

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Impact of Yoga on Haemodynamic Function in Healthy Medical Students

Issue:

Vol 60, issue 2 (2011)

Pages:

148–52

Synopsis:

Yoga is a healing system of theory and practice, and is a combination of breathing exercises, physical postures, and meditation. Its practice, even for a short period, shows the capability to improve most of the cardiovascular functions in young healthy adults.

ABSTRACT

Objectives: Yoga improves cardiovascular health in both healthy individuals and those with diagnosed heart disease. This study compares changes in some cardiovascular parameters before and after the practice of Yoga in healthy medical students.

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The Predictive Value of Urinary Vanillylmandelic Acid Testing in the Diagnosis of Phaeochromocytoma at The University Hospital of the West Indies

Issue:

Vol 60, issue 2 (2011)

Pages:

141–7

Synopsis:

Vanillylmandelic acid testing at the University Hospital of the West Indies has low positive predictive value, and special care must be taken in interpreting marginally elevated results. The use of assays with higher specificity (eg plasma or urinary metanephrines) may represent a more cost-effective approach to biochemical screening for phaeochromocytoma.

ABSTRACT

Objective: To investigate the positive predictive value (PPV) of urinary vanillylmandelic acid (VMA) testing in the diagnosis of phaeochromocytoma and to describe the features associated with phaeochromocytoma at the University Hospital of the West Indies (UHWI).

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vanillylmandelic acid.

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e-Published: 17 Oct, 2013

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Poverty, Folate Deficiency, Human Immunodeficiency Virus and Ulcerated Vulval Sexually Transmitted Diseases in Jamaica

Issue:

Vol 60, issue 2 (2011)

Pages:

137–40

Synopsis:

Ulcerated sexually transmitted diseases rates in Jamaica are falling; this may be related to successful measures aimed at alleviating poverty and the decrease in HIV with high condom use.

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