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Original Articles

Drug-herb Interaction: Database of Medicinal Plants of the Caribbean, their Indications, Toxicities and Possible Interactions with Conventional Medication

Issue: 
Pages: 
503–8
Synopsis: 
West Indian Drug-herb Interaction Database 0.06 is a comprehensive database of the popular medicinal plants in the Caribbean and is intended to be utilized by primary care physicians and pharmacists. It might mitigate adverse drug reactions resulting from drug-herb interactions. It also provides details on the plants’ locations, preparation, bioactive ingredients, indications, toxic effects and indications.
ABSTRACT
Objective: Healthcare professionals in the Caribbean today know very little about these drug-herb interactions of the popular West Indian medicinal herb practices linked to the immigrants from West Africa and India, and to the indigenous Amerindians. It is the intent of this project to produce a database which comprehensively summarizes indications and possible drug-herb interactions of these
plants. 
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e-Published: 15 Oct, 2013

Effect of Menopause, Anthropometry, Nutrition and Lifestyle on Bone Status of Women in the Northern Mediterranean

Issue: 
Pages: 
494–502
Synopsis: 
In Mediterranean women, effects of menopause, age, anthropometry, nutrition and lifestyle on bone parameters were assessed. Broad Ultrasonic Attenuation and Speed of Sound were negatively predicted by menopause. Numerous effects were determined in postmenopausal compared to premenopausal women.

ABSTRACT

Objective: The purpose of this study was to explore the influence of age, menopause, anthropometry, nutrition and lifestyle on bone status of women of the Northern Mediterranean Region of Croatia, which is considered the Adriatic Coast of Southeast Europe.

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e-Published: 15 Oct, 2013

Progression from Prehypertension to Hypertension in a Jamaican Cohort: Incident Hypertension and its Predictors

Issue: 
Pages: 
486–93
Synopsis: 
Prehypertension is associated with an approximately three-fold increase in the incidence of hypertension over an average four-year follow-up period. Overweight status, older age and female gender are also significant predictors for the development of hypertension.

ABSTRACT

Objectives: To estimate the incidence of hypertension in people with and without prehypertension and determine the factors that predict progression to hypertension.

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e-Published: 15 Oct, 2013

Elements in Human Placentae in Jamaica

Issue: 
Pages: 
479–85
Synopsis: 
Fifty-two placentae of Jamaican mothers, with a mean age of 29 years, at term were collected. Samples were analysed using Instrumental Neutron Activation Analysis for mercury and 9 other elements. Data were correlated with several parameters collected at delivery and by questionnaire data.

ABSTRACT

Aim: To investigate the relationships, if any, between elemental content of the placenta with age of mother, birthweight and the Apgar scores of a neonate.

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e-Published: 15 Oct, 2013

Potassium Channel Openers Exhibit Cross-tolerance with Morphine in Two Experimental Models of Pain

Issue: 
Pages: 
473–8
Synopsis: 
The study suggests that both morphine and potassium channel openers are cross-tolerant, which was assessed using formalin and tail-flick tests. However, such interaction occurs at the level of potassium channels rather than at the level of receptors.

ABSTRACT

Objective: The study was performed to assess the effect of potassium channel openers on morphine tolerance and vice-versa.

Methods: Swiss albino mice of either gender weighing between 25−30 g were used for the study. The study assesses the effect of potassium channel openers (cromakalim, diazoxide and minoxidil) on morphine tolerance and vice-versa, using formalin and tail-flick tests.

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e-Published: 15 Oct, 2013

Human Papilloma Virus Screening by Hybrid Capture II in Chinese Women of Jiangsu Province

Issue: 
Pages: 
469–72
Synopsis: 
Surveying human papilloma virus (HPV) infection in Chinese Women of Jiangsu Province by high-risk HPV DNA test is effective.

ABSTRACT

Objective: To survey Human Papilloma Virus (HPV) infection in Chinese Women of Jiangsu Province and discuss the relationship between HPV and the biology of cervical cancer.

Methods: Two thousand, one hundred and fifty-three sexually active women (including 66 cases of cervical cancer) were selected for high-risk human papilloma virus DNA test with Hybrid Capture II (HCII).

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e-Published: 15 Oct, 2013

Incidence of Childhood Cancer in Trinidad and Tobago

Issue: 
Pages: 
465–8
Synopsis: 
The incidence of childhood cancer in Trinidad and Tobago is lower than that reported in developed countries. There are some unique findings with the incidence of nephroblastoma and the relatively high incidence of leukaemia in three counties.

ABSTRACT

Background: The Government of Trinidad and Tobago is in the process of developing a comprehensive National Oncology Programme. Regarding Paediatric Oncology, it is necessary to characterize this population to adequately direct its development. This report describes the incidence of childhood cancer in Trinidad and Tobago.

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e-Published: 15 Oct, 2013

Age-Specific Incidence of Cancer in Kingston and St Andrew, Jamaica, 2003 – 2007

Issue: 
Pages: 
456–64
Synopsis: 
Cancer registrations in Kingston and St Andrew (2003−2007) have revealed that cancers of the prostate, breast, lung, cervix uteri and large bowel remain the commonest. Malignancies of unknown primary site also feature prominently and require further investigation.

ABSTRACT

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e-Published: 15 Oct, 2013

Death of a HIV-infected Homosexual from Nitrite Inhalants (Poppers)

Issue: 
Pages: 
450–2
Synopsis: 
This is a case report of a homosexual man, with HIV infection, who had used poppers and had a myocardial infarction. Clinicians and the gay press should discourage the use of poppers.

INTRODUCTION

Drugs such as nitrites, methamphetamine, phosphodiesterase type 5 (PDE-5) inhibitors, ketamine, gamma hydroxybutyrate (GHB) and others have long been used as precursors to sex or during sex by some individuals. Nitrites in the form of amyl nitrite have also a long history of use in the treatment of angina pectoris and as antidotes in cyanide poisoning (1, 2).

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e-Published: 07 Oct, 2013

Disclosure of HIV Status among HIV Clinic Attendees in Jamaica

Issue: 
Pages: 
445–9
Synopsis: 
There is a low disclosure rate among HIV clinic attendees. There is a need for prevention interventions focussed on de-stigmatization for both infected and non-infected persons.

ABSTRACT

Objective: This study aimed to examine factors related to disclosure of HIV serostatus among clinic attendees in an outpatient HIV clinic at the University Hospital of the West Indies (UHWI).

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e-Published: 07 Oct, 2013

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