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Original Articles

The Effect of Unripe Carica Papaya Seeds Extract on Serum Profiles of Some Liver Functional Enzymes in Wistar Rat

DOI: 
10.7727/wimj.2016.502
Synopsis: 
Healthy rats were separately administered different doses of aqueous carica papaya seeds extract to evaluate possible alterations in serum liver enzymes levels. Observed fall in serum aminotransferase enzymes level was clearly indicative of possible hepatoprotective properties of carica papaya seed.

ABSTRACT

Received: 
06 Oct, 2017
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon ezewanne_et_al-caria_papaya_seeds_extract_effect_on_serum_liver_enzymes.pdf
Journal Sections: 
Original Articles
Keywords: 
Carica papaya seeds
hepatomodulatory properties
wistar rat
Journal Authors: 
EB Ezenwanne
O Abuda
e-Published: 08 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

A Profile of Central Corneal Thickness (CCT) in Primary Open Angle Glaucoma in Trinidad and Tobago and the Implications

DOI: 
10.7727/wimj.2016.553
Synopsis: 
This study was designed as an observational, prospective longitudinal consecutive series of patients, with primary open angle glaucoma and control, conducted over a one year period. 80.2% of primary open angle glaucoma and 78.3% of controls had CCT <555um; this independently confers a 3.4 fold increased risk of developing glaucoma; both cohorts showed 25% had a family history of glaucoma. This study adds to the body of evidence demonstrating the high multiple risk factors within our population. The author discusses the epidemiological implications and the need for improved efforts towards developing screening programmes, earlier detection and timely intervention.

INTRODUCTION

Received: 
08 Nov, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon lalchan-epidemiology_of_central_corneal_thickness_in_trinidad_and_tobago.pdf
Journal Sections: 
Original Articles
Keywords: 
Central thickness
glaucoma
Trinidad and Tobago
Journal Authors: 
SA Lalchan
e-Published: 08 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Estimation of Oxygen Diffusing Conductance in Different Dissection Portion of the Placental Cotyledon of Passive Smoking Mothers

DOI: 
10.7727/wimj.2016.531
Synopsis: 
This study estimated the amount oxygen that can diffuse across the placenta of the passive, smoking mothers in an Indo-Asian population. There was no significant difference in the total oxygen-diffusing conductance in the placenta of the passive smokers. However, there was an adaptive mechanism taking place in the foetal part of the placenta.

ABSTRACT

Received: 
26 Oct, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon ramesh_et_al-oxygen_diffusion_conductance_in_placental_cotyledon_of_passive_smoking_mothers.pdf
Journal Sections: 
Original Articles
Keywords: 
Indo-Asian population
oxygen-diffusing conductance
passive smoking mothers
placental cotyledons
Journal Authors: 
KN Ramesh
AA Nasaruddin
J Stanslas
N Sivalingam
I Mathavan
e-Published: 02 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Fine-needle-aspiration (FNA) Cytology for SRC Type Breast Cancer: 13 Case Reports

DOI: 
10.7727/wimj.2016.585
Synopsis: 
This study estimated the nature of SRCs in different histological subtype of breast cancer in department of Ultrasound Diagnosis, the affiliated hospital of Qingdao University, Qingdao, China. It was indicated that its presence may not indicate poor prognosis.

ABSTRACT

Objective: To investigate the cytohistological findings of 13 breast carcinoma cases with SRCs

Methods: From January 2006 to August 2015, 13 cases of SRC type breast cancer had undergone FNA cytology examination before excisional biopsy or operation. All the histological sections of each case were confirmed to have at least 20% SRCs in the tumor cells. The clini­copathological features of SRC type breast cancer were investigated.

Received: 
02 Dec, 2016
Revised: 
30 Mar, 2017
PDF Attachment: 
PDF icon zhao_et_al-clinicopathological_profiles_of_srcs_in_breast_cancer.pdf
Journal Sections: 
Original Articles
Keywords: 
Breast cancer
cytology
fine needle aspiration
signet ring cells
Journal Authors: 
C Zhao
X Wang，L Wang
e-Published: 02 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Children with Vesicoureteric Reflux in a Tertiary Level Teaching Hospital

DOI: 
10.7727/wimj.2016.508
Synopsis: 
The current study gives an insight of Vesicoureteric Reflux survical analysis. Moreover predictive factors of Vesicoureteric Reflux were also determined that would lead to kidney failure

ABSTRACT

Objective: To determine the survival analysis of children with Vesicoureteric reflux (VUR) in relation to the development of renal failure, and the associated factor in relation with high grade VUR.

Received: 
13 Oct, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon nzan_et_al-children_with_vesicoureteric_reflux.pdf
Journal Sections: 
Original Articles
Keywords: 
children
renal failure
survival time
vesicoureteric reflux
Journal Authors: 
N Zainal
A Rosmawati
I Mohamad Ikram
A Nasir
AH Khan
RA Aftab
e-Published: 02 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Granulomatous Mastitis: A Diagnostic and Therapeutic Challenge

DOI: 
10.7727/wimj.2016.493
Synopsis: 
Granulomatous mastitis, including idiopathic granulomatous mastitis and tuberculous mastitis poses diagnostic and therapeutic challenges for physicians. Our aim is to highlight the nonspecific clinical presentations, diagnostic difficulties and therapeutic approaches of granulomatous mastitis in a Turkish patient group.

ABSTRACT

Objective: Granulomatous mastitis (GM), including idiopathic granulomatous mastitis (IGM) and tuberculous mastitis (TBM), is a rare and benign disease of the breast. Our aim is to highlight the nonspecific clinical presentations, diagnostic difficulties and therapeutic approaches of GM.

Received: 
29 Sep, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon kilic_et_al-granulomatous_mastitis.pdf
Journal Sections: 
Original Articles
Keywords: 
diagnosis
granulomatous mastitis
idiopathic
tuberculous mastitis
Journal Authors: 
MÖ Kılıç
M Şen
D İçen
e-Published: 02 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Protective Effects of Extracts from Polygonum Hydropiper L on Ethanol-Induced Acute Gastric Mucosal Lesions

DOI: 
10.7727/wimj.2016.503
Synopsis: 
This study was to investigate the protective effect of extracts from Polygonum hydropiper on experimentally-induced AGML in mice. The findings showed that the extract could distinctly reduce the acute gastric mucosal damage, and these are closely associated with antioxidant effect. The extracts enhanced the activities of antioxidative enzymes SOD and GSH-Px and decreased the level of MDA in the serum and gastric tissues. In addition, the extracts increased the production of PGE2 and decreased the NO level in gastric tissues.

ABSTRACT

Received: 
06 Oct, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon ren_et_al-protective_effects_of_polygonum_hydropiper_l.pdf
Journal Sections: 
Original Articles
Keywords: 
Acute gastric mucosal injury
antioxidation
oxidative stress
polygonum hydropiper L extracts
Journal Authors: 
SZ Ren
CL Yang
J Chen
N Wang
WQ Su
L Sheng
ZJ Ma
JH Lei
e-Published: 01 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

A Comparison of Weekly DCF versus Standard DCF as First-line Systemic Chemotherapy for Metastatic Gastric Cancer Patients

Issue: 
Vol 70, Issue 1: 2023
DOI: 
10.7727/wimj.2016.536
Pages: 
18-22
Synopsis: 
In metastatic gastric cancer (MGC), the goals of treatment are palliation and prolongation of overall survival. Systemic chemotherapy, with docetaxel, cisplatin, infusional 5-fluorouracil (DCF) are a commonly used regimen in MGC as first line chemotherapy with a low tolerability rate due to its toxicity. We evaluated the efficacy and tolerability of weekly DCF compared to standard DCF regimen.

ABSTRACT

Received: 
28 Oct, 2016
Accepted: 
30 May, 2017
Published: 
29 Nov, 2023
PDF Attachment: 
PDF icon wimj-iss1-2023_18_22.pdf
Journal Sections: 
Original Articles
Keywords: 
Cisplatin
docetaxel
infusional 5-fluorouracil
metastatic gastric cancer.
Journal Authors: 
MN Aldemir
M Turkeli
M Simsek
N Yildirim
M Bilici
C Dogan
SB Tekin
e-Published: 01 May, 2017

What Are the Factors Affecting on the Mortality of COPD Patients in the ICU?

DOI: 
10.7727/wimj.2016.593
Synopsis: 
Morbidity and mortality rates of COPD are continuously increasing throughout the world. We aimed to determine factors associated with in-hospital-mortality of all causes following critical care admissions of patients with COPD. Features during admission to the ICU of patients were studied such as demographic and clinical features, laboratory analyses and comorbid diseases. Co-morbid diseases such as CHF, AF and postoperative care affect mortality the most in COPD patients who are hospitalized in ICU. Laboratory tests like creatinine and clinical features like being intubated upon admission, duration of mechanical ventilation and EF are other independent variables that affect mortality.

ABSTRACT

Background: Morbidity and mortality rates of Chronic obstructive pulmonary disease (COPD) are continuously increasing throughout the world. It is a major cause of death, imposes a great socioeconomic burden and constitutes a significant part of ICU patients.

Aim: To determine factors associated with in-hospital-mortality of all causes following   critical care admissions of patients with COPD.

Received: 
12 Dec, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon arslan_et_al-mortality_of_copd_patients.pdf
Journal Sections: 
Original Articles
Keywords: 
Co-morbidity
COPD
creatinine
ICU
Mortality
Journal Authors: 
Z Arslan
Ö Özmen
F Karakoc
D Kara
M Naldan
E Uzlaş
E Oral
P Aydın
e-Published: 27 Apr, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Chronic Persistent Hypokalaemia in Children

DOI: 
10.7727/wimj.2016.494
Synopsis: 
This study evaluated the causes of chronic persistent hypokaelemia in children at the University of Jordan. The most common cause of normotensive hypokalaemic metabolic alkalosis was Bartter syndrome.The most common cause of hypokalaemic metabolic acidosis was distal renal tubular acidosis.

ABSTRACT

Objective: Chronic hypokalaemia is a cause of morbidity and mortality. The purpose of this study is to determine the aetiology of chronic hypokalaemia in children at a tertiary care hospital setting.

Methods: Retrospective medical record review of consecutive cases of persistent chronic hypokalaemia of more than three months duration.

Received: 
05 Oct, 2016
Accepted: 
30 Mar, 2017
PDF Attachment: 
PDF icon akl-chronic_hypokalaemia_in_children.pdf
Journal Sections: 
Original Articles
Keywords: 
children
chronic
hypokalemiaetiology
Jordan
Journal Authors: 
K Akl
J Albaramki
e-Published: 27 Apr, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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