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Original Articles

Enhancement of Germ Cell Apoptosis Induced by Chronic Ethanol in Transgenic Mice Overexpressing Fas Ligand

DOI: 
10.7727/wimj.2017.099

ABSTRACT

Objective: To analysis ethanol exposure and its apoptosis results in germline cells.

Accepted: 
08 Jun, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 10 Jul, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Decreased Thiol Levels, Increased Disulphide Levels Are Associated with Increased Blood Glucose Levels in Newly Diagnosed Type 2 Diabetes

DOI: 
10.7727/wimj.2016.590
Synopsis: 
This study examined the thiol/disulphide balance in patients with newly diagnosed T2DM using a newly developed technique. The thiol/disulphide balance, an important marker of oxidative stress, altered towards a decrease in thiol and an increase in disulphide in the newly diagnosed T2DM patient group.

ABSTRACT

Objective: The purpose of this study was to evaluate the relation between newly diagnosed type 2 diabetes and the thiol/disulfide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.

Revised: 
15 Jul, 2017
Accepted: 
30 Jun, 2017
Journal Sections: 
e-Published: 10 Jul, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

2:1 Block with Wenckebach Mechanism in Children Due to Different Etiologies

DOI: 
10.7727/wimj.2016.577
Synopsis: 
Our results suggest that the clues indicating a Wenckebach mechanism in children with 2:1 atrioventricular block (2:1 AVB) can be obtained by noninvasive techniques. In children with sustained 2:1 AVB intracardiac electrophysiological study can help in the differentiation, and the prognosis seems good.

ABSTRACT

Objective: In children 2:1 Atrioventricular Block (AVB) with Wenckebach mechanism is a rare entity.

Subjects and methods: In 7 children, 2:1 Atrioventricular Block (AVB) with Wenckebach mechanism was detected. The clinical features of these children are retrospectively evaluated.

Accepted: 
09 Jul, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 10 Jul, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Estimated Effects of Climate Variables on Transmission of Malaria, Dengue and Leptospirosis within Georgetown, Guyana

DOI: 
10.7727/wimj.2017.118
Pages: 
Synopsis: 
The study suggest a connection between climate variable and vector borne disease. The study showed a positive correlation between climate variables and vector borne diseases like malaria, leptospirosis and dengue.

ABSTRACT

Objective: To analyze meteorological data (temperature, rainfall and relative humidity) and vector borne diseases (malaria, dengue and leptospirosis) to determine trends that may exist between and among variables within the Georgetown area.

Accepted: 
07 Jul, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 07 Jul, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

The Thickness of Epicardial Adipose Tissue Adjacent to the Right Coronary Artery Predicts Recurrence of Atrial Fibrillation After Cryoballoon Ablation: A Simpler Method

Issue: 
DOI: 
10.7727/wimj.2017.070
Pages: 
1-6
Synopsis: 
This study investigated the importance of epicardial fat-tissue round the right coronary artery, highly sensitive C-reactive protein and left atrial volume index on recurrence of atrial fibrillation after cryoballoon ablation.

ABSTRACT

Accepted: 
09 Jun, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 06 Jul, 2017

Dementia among Older Persons in Jamaica: Prevalence and Policy Implications

Issue: 
DOI: 
10.7727/wimj.2017.133
Pages: 
1-8
Synopsis: 
This paper described the prevalence of dementia in the ageing Jamaican population. There are service and policy implications given the increasing importance of providing health and social services for persons with dementia.

ABSTRACT

Objective: To determine the prevalence of dementia and dementia types in Jamaica.

Accepted: 
21 Jun, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 21 Jun, 2017

Expressions of MicroRNA of Mixed Cellularity Hodgkin Lymphomas are Different in Paediatric and Adult Patients

Issue: 
DOI: 
10.7727/wimj.2016.504
Pages: 
565-70
Synopsis: 
This study evaluated the importance of microRNA in classical mixed cellularity Hodgkin lymphoma (MCHL) pathogenesis. We thought that microRNAs may play an important role in the biology of paediatric MCHL and may be useful in developing therapies targeting microRNAs.

ABSTRACT

Objective: MicroRNAs represent an emerging class of small non-coding RNAs that play important roles in the post-transcriptional regulation of gene expression. This study was aimed to evaluate the relevance of microRNA in classical mixed cellularity Hodgkin lymphoma (MCHL) pathogenesis.

Accepted: 
08 Jun, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 20 Jun, 2017

What is Critical Diagnostic Role of Adenoid Hypertrophy and Adult-Onset Otitis Media with Effusion in Clinically Asymptomatic Nasopharyngeal Carcinoma?

DOI: 
10.7727/wimj.2017.098
Synopsis: 
We aimed to investigate the validity of performed nasopharyngeal biopsies to diagnose suspected malignity in adult patients with adenoid hypertrophy whit/without synchronous otitis media with effusion in absence of other clinical symptoms and radiologic findings to arouse suspecting malignancy.

ABSTRACT

Objectives: The aim of this study is to verify the critical role of adenoid hypertrophy and otitis media with effusion in adult patients in relation to diagnostic importance for patients with clinically asymptomatic nasopharyngeal carcinoma.

Accepted: 
09 Jun, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 20 Jun, 2017

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Correlation Study of Insulin Resistance and Adipocytes Factors in Patients with Type 2 Diabetes

DOI: 
10.7727/wimj.2014.382
Synopsis: 
The aim of this study was to investigate the insulin resistance and adipocytes factors in patients with Type 2 diabetes. The results of stepwise regression analysis showed that resistin, TNF-α and FFA were significantly associated with insulin resistance index (IRI).

ABSTRACT

Objective: Thirty cases of non-obese patients with type 2 diabetes, 30 cases of obese patients with type 2 diabetes and 30 cases of healthy controls were selected to detect the levels of serum resistin, TNF-α, FFA, fasting blood glucose, fasting insulin, total cholesterol and triglycerides.

Accepted: 
23 Mar, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 15 Jun, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

An Assessment of the Accuracy of Creatinine Measurements in Guyana

Issue: 
DOI: 
10.7727/wimj.2015.518
Pages: 
4-8
Synopsis: 
The accuracy of creatinine measurements in 16 Guyanese medical laboratories was assessed using blinded creatinine reference specimens. Creatinine methods in use in Guyana demonstrated imprecision and bias such that routine reporting of estimated glomerular filtration rates cannot be recommended at this time.

ABSTRACT

Background: The incidence of chronic kidney disease (CKD) is relatively high in Guyana. Estimated glomerular filtration rate (eGFR) reporting allows for early-stage CKD identification when therapeutic interventions can prevent CKD progression. Accurate creatinine measurements are essential for valid eGFR calculations.

Accepted: 
26 Oct, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 01 Jun, 2017

Pages

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