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Original Articles

Decreased Thiol Levels, Increased Disulphide Levels Are Associated with Increased Blood Glucose Levels in Newly Diagnosed Type 2 Diabetes

DOI: 
10.7727/wimj.2016.590
Synopsis: 
This study examined the thiol/disulphide balance in patients with newly diagnosed T2DM using a newly developed technique. The thiol/disulphide balance, an important marker of oxidative stress, altered towards a decrease in thiol and an increase in disulphide in the newly diagnosed T2DM patient group.

ABSTRACT

Objective: The purpose of this study was to evaluate the relation between newly diagnosed type 2 diabetes and the thiol/disulfide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.

Received: 
09 Dec, 2016
Revised: 
15 Jul, 2017
Accepted: 
30 Jun, 2017
Journal Sections: 
Original Articles
Keywords: 
Disufide
newly diagnosed Type 2 diabetes mellitus
oxidative stres
thiol
Journal Authors: 
M Senyurt
S Neselioglu
CK Bicer
F Yildiz
H Gözcü
A Carlıoglu
e-Published: 10 Jul, 2017

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

2:1 Block with Wenckebach Mechanism in Children due to Different Etiologies

Issue: 
Vol 72, Issue 1: 2025
DOI: 
10.7727/wimj.2016.577
Pages: 
22-4
Synopsis: 
Our results suggest that the clues indicating a Wenckebach mechanism in children with 2:1 atrioventricular block (2:1 AVB) can be obtained by noninvasive techniques. In children with sustained 2:1 AVB intracardiac electrophysiological study can help in the differentiation, and the prognosis seems good.

ABSTRACT

Objective: In children, 2:1 atrioventricular block (AVB) with Wenckebach mechanism is a rare entity.

Methods: In seven children, 2:1 AVB with Wenckebach mechanism was detected. The clinical features of these children were retrospectively evaluated.

Received: 
21 Nov, 2016
Accepted: 
09 Jul, 2017
Published: 
21 Dec, 2025
PDF Attachment: 
PDF icon wimj-iss1-2025_22_24.pdf
Journal Sections: 
Original Articles
Keywords: 
2:1 Atrioventricular block
Bradycardia
children
Wenckebach.
Journal Authors: 
F Laloglu
N Ceviz
H Keskin
H Olgun
e-Published: 10 Jul, 2017

Estimated Effects of Climate Variables on Transmission of Malaria, Dengue and Leptospirosis within Georgetown, Guyana

Issue: 
Vol 72, Issue 1: 2025
DOI: 
10.7727/wimj.2017.118
Pages: 
42-6
Synopsis: 
The study suggests a connection between climate variables and vector-borne disease. The study showed a positive correlation between climate variables and vector-borne diseases like malaria, leptospirosis, and dengue.

ABSTRACT

Objective: To analyse meteorological data (temperature, rainfall and relative humidity) and vector-borne diseases (malaria, dengue and leptospirosis) to determine trends that may exist between and among variables within the Georgetown area.

Received: 
02 Jun, 2017
Accepted: 
07 Jul, 2017
Published: 
21 Dec, 2025
PDF Attachment: 
PDF icon wimj-iss1-2025_42_46.pdf
Journal Sections: 
Original Articles
Keywords: 
Dengue
Climate Change
Leptospirosis
Malaria
Journal Authors: 
C Boston
R Kurup
e-Published: 07 Jul, 2017

The Thickness of Epicardial Adipose Tissue Adjacent to the Right Coronary Artery Predicts Recurrence of Atrial Fibrillation After Cryoballoon Ablation: A Simpler Method

Issue: 
Vol 68, Issue 1: 2019
DOI: 
10.7727/wimj.2017.070
Pages: 
1-6
Synopsis: 
This study investigated the importance of epicardial fat-tissue round the right coronary artery, highly sensitive C-reactive protein and left atrial volume index on recurrence of atrial fibrillation after cryoballoon ablation.

ABSTRACT

Received: 
03 Mar, 2017
Accepted: 
09 Jun, 2017
Published: 
07 Oct, 2019
PDF Attachment: 
PDF icon wimj-iss1-2019_1_6.pdf
Journal Sections: 
Original Articles
Keywords: 
atrial fibrillation
cryoballoon ablation
epicardial adipose tissue
recurrence
Journal Authors: 
NS Yelgeç
S Sahin
AT Alper
e-Published: 06 Jul, 2017

Dementia among Older Persons in Jamaica: Prevalence and Policy Implications

Issue: 
Vol 67, Issue 1: 2018
DOI: 
10.7727/wimj.2017.133
Pages: 
1-8
Synopsis: 
This paper described the prevalence of dementia in the ageing Jamaican population. There are service and policy implications given the increasing importance of providing health and social services for persons with dementia.

ABSTRACT

Objective: To determine the prevalence of dementia and dementia types in Jamaica.

Received: 
20 Jun, 2017
Accepted: 
21 Jun, 2017
Published: 
22 Apr, 2018
PDF Attachment: 
PDF icon wimj-iss1-2018_1_8.pdf
Journal Sections: 
Original Articles
Keywords: 
ageing
Alzheimer’s disease
Dementia
prevalence
Journal Authors: 
D Eldemire-Shearer
K James
P Johnson
R Gibson
D Willie-Tyndale
e-Published: 21 Jun, 2017

Expressions of MicroRNA of Mixed Cellularity Hodgkin Lymphomas are Different in Paediatric and Adult Patients

Issue: 
Vol 69, Issue 8: 2022
DOI: 
10.7727/wimj.2016.504
Pages: 
565-70
Synopsis: 
This study evaluated the importance of microRNA in classical mixed cellularity Hodgkin lymphoma (MCHL) pathogenesis. We thought that microRNAs may play an important role in the biology of paediatric MCHL and may be useful in developing therapies targeting microRNAs.

ABSTRACT

Objective: MicroRNAs represent an emerging class of small non-coding RNAs that play important roles in the post-transcriptional regulation of gene expression. This study was aimed to evaluate the relevance of microRNA in classical mixed cellularity Hodgkin lymphoma (MCHL) pathogenesis.

Received: 
26 May, 2017
Accepted: 
08 Jun, 2017
Published: 
20 Jul, 2022
PDF Attachment: 
PDF icon wimj-iss8-2022_565_570.pdf
Journal Sections: 
Original Articles
Keywords: 
Children and adults
microRNA
mixed cellularity Hodgkin lymphoma
Journal Authors: 
S Aktas
G Diniz
M Ceyhan
H Tosun-Yildirim
C Ceylan
Y Oymak
D Solakoglu- Kahraman
B Demirag
H Oniz
N Olgun
e-Published: 20 Jun, 2017

What is the Diagnostic Role of Adenoid Hypertrophy and Adult-Onset Otitis Media with Effusion in Clinically Asymptomatic Nasopharyngeal Carcinoma?

Issue: 
Vol 71, Issue 1: 2024
DOI: 
10.7727/wimj.2017.098
Pages: 
19-23
Synopsis: 
We aimed to investigate the validity, in adult patients, of adenoid hypertrophy with/without synchronous otitis media with effusion, in absence of other clinical symptoms and radiologic findings, to arouse suspicion of nasopharyngeal malignancy.

ABSTRACT

Objectives: To verify the role of adenoid hypertrophy (AH) and otitis media with effusion (OME) in adult patients, in relation to the diagnosis of clinically asymptomatic nasopharyngeal carcinoma (NPC).

Received: 
13 Apr, 2017
Accepted: 
09 Jun, 2017
Published: 
30 Mar, 2024
PDF Attachment: 
PDF icon wimj-iss1-2024_19_23.pdf
Journal Sections: 
Original Articles
Keywords: 
adenoid hypertrophy
Adult
Nasopharyngeal carcinoma
otitis media with effusion
Journal Authors: 
OI Ozdamar
GO Acar
M Tekin
e-Published: 20 Jun, 2017

Correlation Study of Insulin Resistance and Adipocytes Factors in Patients with Type 2 Diabetes

DOI: 
10.7727/wimj.2014.382
Synopsis: 
The aim of this study was to investigate the insulin resistance and adipocytes factors in patients with Type 2 diabetes. The results of stepwise regression analysis showed that resistin, TNF-α and FFA were significantly associated with insulin resistance index (IRI).

ABSTRACT

Objective: Thirty cases of non-obese patients with type 2 diabetes, 30 cases of obese patients with type 2 diabetes and 30 cases of healthy controls were selected to detect the levels of serum resistin, TNF-α, FFA, fasting blood glucose, fasting insulin, total cholesterol and triglycerides.

Received: 
12 Dec, 2014
Accepted: 
23 Mar, 2015
PDF Attachment: 
PDF icon li_et_al-insulin_resistance_and_adipocytes_factors.pdf
Journal Sections: 
Original Articles
Keywords: 
Adipokines
FFA
insulin resistance
resistin
tumor necrosis factor
Type 2 diabetes
Journal Authors: 
W-X Li
Q-Y Dong
C-G Liang
W-H Du
Y-L Wang
G Gao
e-Published: 15 Jun, 2017

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

An Assessment of the Accuracy of Creatinine Measurements in Guyana

Issue: 
Vol 69, Issue 1: 2021
DOI: 
10.7727/wimj.2015.518
Pages: 
4-8
Synopsis: 
The accuracy of creatinine measurements in 16 Guyanese medical laboratories was assessed using blinded creatinine reference specimens. Creatinine methods in use in Guyana demonstrated imprecision and bias such that routine reporting of estimated glomerular filtration rates cannot be recommended at this time.

ABSTRACT

Background: The incidence of chronic kidney disease (CKD) is relatively high in Guyana. Estimated glomerular filtration rate (eGFR) reporting allows for early-stage CKD identification when therapeutic interventions can prevent CKD progression. Accurate creatinine measurements are essential for valid eGFR calculations.

Received: 
13 Oct, 2015
Accepted: 
26 Oct, 2015
Published: 
30 Apr, 2021
PDF Attachment: 
PDF icon wimj-iss1-2021_4_8.pdf
Journal Sections: 
Original Articles
Keywords: 
chronic kidney disease
creatinine
estimated glomerular filtration rate
Guyana
standardization
Journal Authors: 
JL Shaw
YP Irving
B Jacobson
DW Seccombe
e-Published: 01 Jun, 2017

Worse Chronic Obstructive Pulmonary Disease Outcomes in Patients Who Smoke Both Tobacco and Marijuana

DOI: 
10.7727/wimj.2017.080
Synopsis: 
We compared the clinical course and outcomes for the patients admitted for Chronic Obstructive Pulmonary Disease (COPD) who smoked tobacco and marijuana versus tobacco only. The results showed earlier onset of advanced COPD with more frequent progression to cor pulmonale and death in tobacco and marijuana smokers.

ABSTRACT

Objective: To compare clinical course and outcomes in patients admitted for Chronic Obstructive Pulmonary Disease (COPD) who smoke tobacco plus marijuana versus tobacco only.

Received: 
14 Mar, 2017
Accepted: 
31 Mar, 2017
PDF Attachment: 
PDF icon charles_et_al-clinical_outcomes_in_tobacco_and_marijuana_smokers_with_copd.pdf
Journal Sections: 
Original Articles
Keywords: 
COPD
chronic obstructive pulmonary disease
cor pulmonale
tobacco and marijuana smoking
Journal Authors: 
LM Charles
MS Ambrose
M Didier
C Nathaniel
e-Published: 31 May, 2017

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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