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Original Articles

Antidepressant-like Effect of EGb 761 in Rats with Chronic Mild Stress-induced Depressive Behaviors

DOI: 
10.7727/wimj.2015.087
Synopsis: 
EGb 761 possesses antidepressant activity in rats exposed to CMS. Besides, it can partially reverse the alterations of IL-1β, IL-6, VEGF and HPA axis dysfunction induced by CMS in rats.

ABSTRACT

Objective: The aims were to investigate the effects of EGb 761 on depressive behaviors in rats exposed to chronic mild stress (CMS) and the possible mechanisms of the actions.

Received: 
23 Feb, 2015
Accepted: 
26 Mar, 2015
PDF Attachment: 
PDF icon hua_et_al-antidepressant-like_effect_of_egb_761.pdf
Journal Sections: 
Original Articles
Keywords: 
Depression
Inflammation
Antidepressant-like effect
chronic mild stress
EGb 761
HPA axis
VEGF
Journal Authors: 
L Hua
L Limei
W Chunyan
L Zhonggang
Y Kuitao
e-Published: 18 Sep, 2015

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

The Relationship between Serum IL-17 and IL-23 Levels, and Other Disease Activity Parameters in Patients with Behçet’s Disease

Issue: 
Vol 69, Issue 9: 2023
DOI: 
10.7727/wimj.2015.248
Pages: 
624-7
Synopsis: 
This study focuses on Behçet’s disease, a vasculitic syndrome with unknown aetiopathogenesis including genetic factors, infections and cytokines. IL17 and IL 23 play important roles in inflammatory diseases such as psoriasis, rheumatoid arthritis, multiple sclerosis, inflammatory bowel diseases, asthma, bacterial, fungal infections, maybe Behçet’s disease.

ABSTRACT

Objective: To investigate the relationship between disease activity and the involvement of Behçet’s disease (BD) and serum levels of interleukin (IL)-17 and IL-23.

Received: 
20 May, 2015
Accepted: 
20 Aug, 2015
Published: 
25 Jan, 2023
PDF Attachment: 
PDF icon wimj-iss9-2023_624_627.pdf
Journal Sections: 
Original Articles
Keywords: 
Behçet’s Disease
interleukin-17
interleukin-23
Journal Authors: 
O Küçükşahin
A Şahin
MT Yıldızgören
M Turgay
G Kinikli
e-Published: 18 Sep, 2015

Trends of Mortality and Causes of Death among HIV-infected Persons in Guadeloupe: 1988–2009

DOI: 
10.7727/wimj.2015.369
Synopsis: 
The causes of deaths reported in the literature were similar to those observed in our study. In contrast with metropolitan France where cancer represented the first cause of death, in Guadeloupe, AIDS-related infections were the first cause of deaths.

ABSTRACT

Received: 
06 Jul, 2015
Accepted: 
10 Sep, 2015
PDF Attachment: 
PDF icon elenga_et_al-mortality_trends_in_hiv-infected_people.pdf
Journal Sections: 
Original Articles
Keywords: 
risk factors
Guadeloupe
HIV-infected patients
causes
Journal Authors: 
N Elenga
M-T Georger-Sow
T Messiaen
I Lamaury
I Favre
M Nacher
G Beaucaire
e-Published: 18 Sep, 2015

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Application of Two-Stage Hybrid Coronary Revascularization in Multivessel Coronary Artery Disease

DOI: 
10.7727/wimj.2015.425
Synopsis: 
Two-stage HCR is a safe, effective and minimally invasive method to treat multivessell CAD

ABSTRACT

Objective: The aim of this study was to explore the efficacy of percutaneous coronary intervention (PCI) with minimally invasive direct coronary artery bypass grafting (MIDCABG) in the treatment for multivessel coronary artery disease (CAD).

Received: 
03 Aug, 2015
Accepted: 
11 Sep, 2015
PDF Attachment: 
PDF icon gao20et20al-20application20of20two-stage20hybrid20coronary20revascularization1.pdf
Journal Sections: 
Original Articles
Keywords: 
Drug-eluting stent
hybrid coronary
minimally invasive direct coronary artery bypass grafting
percutaneous coronary intervention
Journal Authors: 
Z Gao
L Xiao
Y Wang
M Yang
Y Zhang
H Li
J Zhou
Y Ling
e-Published: 18 Sep, 2015

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Treatment of Parapelvic Cyst by Internal Drainage Technology Using Ureteroscope and Holmium Laser

Issue: 
Vol 64, Issue 3: June (2015)
DOI: 
10.7727/wimjopen.2014.220
Pages: 
230–5
Synopsis: 
We explored the efficacy and safety of surgical approaches with holmium laser ureteroscopic internal drainage in the treatment of parapelvic cyst. In 28 cases of operation, 27 cases were successful. Our study shows that the treatment of parapelvic cyst by internal drainage operation using holmium laser and ureteroscopy had very good result with few complications.

ABSTRACT

Background: The aim of parapelvic cyst treatment is to have complete drainage of cyst fluid and prevent its further compression of the kidney and collective system. This study explores the efficacy and safety of surgical approaches with holmium laser ureteroscopic internal drainage in the treatment of parapelvic cyst.

Received: 
28 Apr, 2014
Accepted: 
17 Sep, 2014
PDF Attachment: 
PDF icon wimjjun2015_230_235.pdf
Journal Sections: 
Original Articles
Keywords: 
Holmium laser
parapelvic cyst
ureteroscopy
Journal Authors: 
Q Zhao
S Huang
Q Li
L Xu
X Wei
S Huang
S Li
Z Liu
e-Published: 14 Sep, 2015

Application of Modified Glomerular Filtration Rate Estimation Equations in Chinese Diabetic Patients with Chronic Kidney Diseases

Issue: 
Vol 64, Issue 3: June (2015)
DOI: 
10.7727/wimjopen.2014.273
Pages: 
209–12
Synopsis: 
The Ruijin equation is more applicable in Chinese diabetic and chronic kidney diseases patients than the Cockcroft-Gault and Modification of Diet in Renal Disease formulae.
ABSTRACT
 
Objective: To evaluate the applicability of modified formulae based on plasma creatinine levels in Chinese diabetic patients with chronic kidney diseases (CKD).
Received: 
15 Oct, 2014
Accepted: 
31 Oct, 2014
PDF Attachment: 
PDF icon wimjjun2015_209_212.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes
glomerular filtration rate
Chronic kidney diseases
Journal Authors: 
H Chang
SD YE
e-Published: 14 Sep, 2015

Incidental Cancer in Benign Thyroid Disease: An Experience at the University Hospital of the West Indies

Issue: 
Vol 66, Issue 2: 2017
DOI: 
10.7727/wimj.2015.167
Pages: 
329–34
Synopsis: 
The prevalence of cancer in multinodular goitre in Jamaica is lower than other prevalences seen worldwide of incidental thyroid cancer. It is seen more commonly in the middle aged females and are most commonly of the papillary type.

ABSTRACT

Received: 
20 Mar, 2015
Accepted: 
26 Mar, 2015
Published: 
22 Sep, 2017
PDF Attachment: 
PDF icon wimj-iss2-2017_329_334.pdf
Journal Sections: 
Original Articles
Keywords: 
incidental thyroid cancer
Incidentalomas
multinodular goitre
Journal Authors: 
R Forde
M Brown
A Mitchell
e-Published: 08 Sep, 2015

Acute Complicated Sinusitis: Ten Years Experience from the University Hospital of the West Indies

Issue: 
Vol 66, Issue 2: 2017
DOI: 
10.7727/wimj.2015.156
Pages: 
318–23
Synopsis: 
Acute sinusitis has been associated with complications and has been seen most frequently in the adolescent male population. The most common complication is orbital. Surgical techniques have evolved from open sinus approaches to endoscopic approaches. Surgical treatment is indicated for those patients who fail medical management and should consist of an endoscopic approach which may be combined with open approaches if indicated.

ABSTRACT

Objective: Complicated sinusitis is rare. It might not be identified early and might expose the patient to an unfavourable outcome. There is a paucity of data regarding this condition in the Caribbean. This study was undertaken to describe the clinical characteristics and treatment outcomes of patients admitted with this condition.

Received: 
19 Mar, 2015
Accepted: 
25 Mar, 2015
Published: 
22 Sep, 2017
PDF Attachment: 
PDF icon wimj-iss2-2017_318_323.pdf
Journal Sections: 
Original Articles
Keywords: 
Acute sinusitis
complicated sinusitis
functional endoscopic sinus surgery
rhinosinusitis
Journal Authors: 
R Forde
W Mullings
P Brown
EW Williams
e-Published: 08 Sep, 2015

Adult Epistaxis, Epidemiology and Management at the University Hospital of The West Indies

Issue: 
Vol 66, Issue 1: 2017
DOI: 
10.7727/wimj.2015.007
Pages: 
100–04
Synopsis: 
Epistaxis is stated as one of the most common otolaryngology emergencies. Minor epistaxis originates from the anterior septum and is secondary to nose picking in children and dessication of the mucosa in adults from dry air. Major epistaxis lacks a precise definition but is characterised as being difficult for patients to control which results in a visit to the emergency department. There is a high prevalence of elevated blood pressure readings and hypertension among our patients with epistaxis. Most cases of epistaxis can be managed successfully with non-surgical treatment.

ABSTRACT

Received: 
20 Jan, 2015
Accepted: 
05 Feb, 2015
Published: 
08 Mar, 2017
PDF Attachment: 
PDF icon wimjiss12017_100_104.pdf
Journal Sections: 
Original Articles
Keywords: 
Anterior nose bleed
epistaxis
nasal packing
posterior nose bleed
Journal Authors: 
R Forde
R Cargill
A Batchelor
EW Williams
e-Published: 08 Sep, 2015

The Investigation of Plasma Glucagon-like Peptide-1 Levels in Newly Diagnosed Type 1 Diabetic Children

Issue: 
Vol 65, Issue 1: 2016
DOI: 
10.7727/wimj.2014.134
Pages: 
141–6
Synopsis: 
Fasting and postprandial glucagon-like peptide-1 (GLP-1) and C-peptide levels in 25 newly diagnosed Type 1 diabetic children were not different from 22 healthy children used as control. This suggests that plasma GLP-1 levels play no role in the pathogenesis of Type 1 diabetes.

Abstract

Objective: To reveal the possible role of glucagon-like peptide-1 (GLP-1) in newly diagnosed Type 1 diabetic children.

Methods: Twenty-five newly diagnosed children and 22 healthy children were included in the study.

Received: 
27 May, 2014
Accepted: 
26 Sep, 2014
PDF Attachment: 
PDF icon wimj_iss1_2016_141_146.pdf
Journal Sections: 
Original Articles
Keywords: 
children
C-peptide
type 1 diabetes mellitus
glucagon-like peptide-1
Journal Authors: 
B Uslu
F Gurbuz
F Temiz
B Yuksel
N Mungan
AK Topaloglu
e-Published: 03 Sep, 2015

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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