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Sickle Cell Disease

Clinical Factors Associated With Morbidity and Mortality in Patients Admitted with Sickle Cell Disease

Issue: 
DOI: 
10.7727/wimj.2014.012
Pages: 
711–6
Synopsis: 
Sickle cell disease still carries a high morbidity and mortality in patients admitted to hospital. Recurrent admissions are a concern, as this impact on patient’s morbidity and quality of life.

ABSTRACT

Objective: To determine the clinical factors associated with the length of hospitalization and mortality in patients with sickle cell disease (SCD).

Accepted: 
28 Feb, 2014
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e-Published: 05 Mar, 2015

The Use of Analgesic Drugs in Patients with Sickle Cell Painful Crisis

Issue: 
DOI: 
10.7727/wimj.2012.272
Pages: 
479–83
Synopsis: 
Painful crisis in patients with sickle cell anaemia is associated with severe pain in 75% and most will require second line therapy for adequate resolution. Physicians need to provide adequate pain relief to decrease morbidity in these patients.

ABSTRACT

Objective: To determine the drug options used for pain in patients with acute sickle cell painful crisis at the University Hospital of the West Indies (UHWI), Jamaica.

Method: This retrospective study assessed all patients admitted to the UHWI between January 1, 2006 and December 31, 2010 with acute sickle cell anaemia painful crisis and the data obtained regarding site, severity, outcome and drug options selected for pain.

Revised: 
24 Feb, 2013
Accepted: 
12 Mar, 2013
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e-Published: 30 Apr, 2014

Jamaica, the Caribbean and Sickle Cell Disease

Issue: 
Pages: 
331–7
Synopsis: 
The development of research interests in sickle cell disease has been traced from the first recorded case, the founding of the University Hospital of the West Indies and the Jamaica Sickle Cell Unit with its worldwide influence on clinical practice in this disease.

ABSTRACT

The development of research interests in sickle cell disease has been traced from the first recorded case, the founding of the University Hospital of the West Indies and the Jamaican Sickle Cell Unit with its influence on clinical practice in this disease worldwide.

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e-Published: 21 Aug, 2013

Cannabinoids and Cannabis Based Medicines in the Treatment of Chronic Pain: A Review

DOI: 
10.7727/wimj.2016.513
Synopsis: 
Anecdotal and traditional use has long proclaimed the use of cannabis in the management of a number of pain conditions. The article outlines the use of cannabinoids and cannabis based medicines in the treatment of chronic pain.

ABSTRACT

Accepted: 
11 Jan, 2017
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e-Published: 25 Jan, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Pattern of Pregnancy Weight Gain in Homozygous Sickle Cell Disease and effect on Birth Size

Issue: 
Pages: 
36–40
Synopsis: 
Maternal weight gain between 25–30 weeks gestation correlates positively with birthweight among AA mothers but appears delayed beyond 30 weeks in SS mothers.

ABSTRACT

Objective: To assess pregnancy weight gain and newborn anthropometry in mothers with homozygous sickle cell (SS) disease and normal controls.

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e-Published: 17 Oct, 2013

The Prevalence of Marijuana Smoking in Young Adults with Sickle Cell Disease: A Longitudinal Study

Issue: 
Pages: 
224–7
Synopsis: 
A history of marijuana smoking was common in young adults with sickle cell disease. Usage increased between 2000 and 2004, and was seldom for medicinal purposes.

ABSTRACT

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e-Published: 10 Jun, 2013

Subjective Well-being of Adults with Homozygous Sickle Cell Disease in Jamaica

Issue: 
Pages: 
181–7
Synopsis: 
Advances in treatment of sickle cell disease have improved the prognosis for patients. As these patients are living longer, issues of subjective well-being become important. Past studies have mostly focussed on patients’ negative life experiences. This study examines both patients’ positive and negative experiences, as well as their satisfaction with life.

ABSTRACT

Objectives: This study compared the subjective well-being of adults with homozygous sickle cell (SS) disease to a matched group of healthy adult peers. The differential influence of sociodemographic factors on the subjective well-being of Sickle Cell patients was also examined.

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e-Published: 17 Oct, 2013

Iron Deficiency Anaemia in Jamaican Children, Aged 1–5 Years, with Sickle Cell Disease

Issue: 
Pages: 
292–6
Synopsis: 
Iron deficiency anaemia (IDA) occurs in children with sickle cell disease (SCD) in Jamaica. Further studies are needed to determine whether treatment of IDA in children with SCD reduces morbidity and is associated with clinical benefits such as improvement in neurocognitive function.

ABSTRACT

Objective: The aim of this study was to determine, using a combination of measures, the prevalence of iron deficiency anaemia (IDA) in children under five years-of-age who have sickle cell disease (SCD) and attend the Sickle Cell Clinic (SCU) of the Tropical Medicine Research Institute.

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e-Published: 06 Jun, 2013

Laparoscopic Cholecystectomy for Chronic Cholecystitis in Jamaican Patients with Sickle Cell Disease: Preliminary Experience

Issue: 
Pages: 
22–4
Synopsis: 
Acute chest syndrome remains a significant problem in patients with sickle cell disease subjected to laparoscopic cholecystectomy.

ABSTRACT

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e-Published: 06 Jun, 2013

A Survey of the Pain Management of Acute Painful Crisis among Patients with Sickle Cell Disease at Two Centres in Jamaica

Issue: 
DOI: 
10.7727/wimj.2013.333
Pages: 
252–7
Synopsis: 
Evidence suggests that acute painful crisis (APC) can be managed safely and effectively in the outpatient setting. This survey reviewed the management of APC at two outpatient centres on the Mona campus of the University of the West Indies.
 

ABSTRACT

Objectives: The aim of this survey was to establish the pain management approaches to acute painful crisis (APC) in sickle cell patients at two healthcare facilities and to compare with available guidelines.

Accepted: 
12 Feb, 2014
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e-Published: 12 Jun, 2014

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