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High Genetic Diversity in Human Immunodeficiency Virus – Type 1 in Jamaica

Issue: 
Pages: 
195–200
Synopsis: 
Molecular analysis of 53 strains of human immunodeficiency virus type-1(HIV-1) from Jamaican patients revealed the presence of several subtypes and a high genetic diversity of the virus in Jamaica.

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e-Published: 18 Sep, 2013

Rotavirus Vaccine Trial in Jamaica

Issue: 
Pages: 
405–7
Synopsis: 
Rotaviruses have been a significant cause of dehydrating gastroenteritis, contributing to infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine trial. This pentavalent vaccine was found to significantly reduce rotavirus-attributable emergency room visits and hospitalizations, without increasing the rates of intussusception or other serious adverse events in Jamaican infants.

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e-Published: 21 Aug, 2013

Eliminating Vertically-transmitted HIV/AIDS while Improving Access to Treatment and Care for Women, Children and Adolescents in Jamaica

Issue: 
Pages: 
396–404
Synopsis: 
Over the past nine years, Jamaica has made excellent strides to eliminate vertically transmitted HIV/AIDS, while reducing the HIV-attributable morbidity and mortality in pregnant women and in HIV-infected children. Continued successful transition of HIV-infected children through adolescence into adulthood will require a strong multidisciplinary team approach.

ABSTRACT

Background and Methods: To celebrate Jamaica’s 50th birthday after receiving independence from Great Britain, we summarize our collaborative published research in the prevention, treatment and care of paediatric, perinatal and adolescent HIV/AIDS in Jamaica.

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e-Published: 21 Aug, 2013

HIV Infection, Sexual Abuse and Social Support in Jamaican Adolescents Referred to a Psychiatric Service

Issue: 
Pages: 
307–11

ABSTRACT

Background: Children and adolescents with HIV/AIDS often have psychological/psychiatric issues that require specialist intervention. We explored whether HIV infection acquired through sexual abuse led to particularly negative psychiatric outcomes and whether good social support is a protective factor in the development of undesirable psychiatric sequelae.

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e-Published: 19 Jul, 2013

Bacille Calmette-Guérin Lymphadenitis and Immune Reconstitution Syndrome in HIV-infected Children on Antiretroviral Therapy in Jamaica

Issue: 
Pages: 
302–6

ABSTRACT

The immune reconstitution inflammatory syndrome (IRIS) is a recognized complication associated with opportunistic infections occurring in HIV-infected individuals after the initiation of highly active antiretroviral therapy (HAART). We report on three HIV-infected infants with rapid progressor HIV disease who present with IRIS due to the BCG vaccine and occurring 3–6 weeks after initiation of HAART.

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e-Published: 19 Jul, 2013

Isoniazid-resistant Disseminated Mycobacterium Tuberculosis in a Jamaican Infant with HIV/AIDS

Issue: 
Pages: 
298–301

ABSTRACT

A case report of isoniazid-resistant disseminated tuberculosis in a young child perinatally co-infected with human immunodeficiency virus (HIV-1) and the challenges managing this child in a resource-constrained setting.

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e-Published: 19 Jul, 2013

Predictors of HIV/AIDS Confirmation and Differences by Guardian Status in HIV+ Adolescents in Jamaica

Issue: 
Pages: 
287–92

ABSTRACT

Background: Approximately 25% of the cumulative AIDS cases in Jamaica involve adolescents and young adults. However, the lives of adolescents living with HIV within Jamaica and the Caribbean have been understudied.

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e-Published: 19 Jul, 2013

Voices of the Women: Feedback from Women of Child-bearing Age who are Living with HIV can help Improve Efficacy of Psychosocial Interventions

Issue: 
Pages: 
274–81

ABSTRACT

Background: We hypothesized that voluntary counselling and testing during pregnancy are necessary but not sufficient to provide the holistic psychosocial support needed by Jamaican women living with HIV and/or AIDS. Based on this hypothesis, we investigated a range of coping methods and support systems used by HIV-infected women and a group of their HIV-negative counterparts before, during and immediately after their pregnancies.

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e-Published: 19 Jul, 2013

HIV-related Mortality in Jamaican Children

Issue: 
Pages: 
265–8

ABSTRACT

Objective: Paediatric HIV is a leading cause of morbidity and mortality worldwide. We describe HIVrelated mortality in a cohort of HIV-infected Jamaican children and identified factors which influenced survival.

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e-Published: 19 Jul, 2013

Clinical Manifestations of Adolescents with HIV/AIDS in Jamaica

Issue: 
Pages: 
257–64

ABSTRACT

Objective: To characterize the clinicopathological manifestations and outcomes of a cohort of HIV-infected Jamaican adolescents.

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e-Published: 19 Jul, 2013

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