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Original Articles

Prediction of Normal Ovulation by Sonographic Folliculometry Involving Natural Cycles among Women in Ojo, Southwest Nigeria

Issue: 
DOI: 
10.7727/wimj.2014.103
Pages: 
134–40
Synopsis: 
Accurate prediction of ovulation is important in the management of female infertility. Sonographic observation of complete disappearance of a dominant follicle and reduction in follicular size of surrogate follicles after follicular rupture appeared to be more reliable predictors of imminent ovulation than merely measuring follicular dimensions.

ABSTRACT

Background: Accurate prediction of ovulation is important in the management of female infertility.

Aim: To determine the sonographic sensitivity of reduction in follicular size and disappearance of ovarian follicle as predictors of imminent ovulation.

Accepted: 
26 Sep, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 13 May, 2015

Evaluation of Health-related Quality of Life in Paediatric Patients with Acute Lymphoblastic Leukaemia

Issue: 
DOI: 
10.7727/wimj.2014.138
Pages: 
277–80
Synopsis: 
The Paediatric Quality of Life Inventory is a widely used instrument to measure paediatric health-related quality of life (HRQOL) in children. In this study, HRQOL scores were significantly lower in patients with acute lymphoblastic leukaemia than in healthy controls.

ABSTRACT

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Global Registry of Acute Coronary Events (GRACE) Risk Score as a Predictor of In-hospital Mortality for Acute Coronary Syndrome in Trinidad and Tobago

Issue: 
DOI: 
10.7727/wimj.2014.172
Pages: 
52–9
Synopsis: 
The GRACE risk score, which was developed in a predominantly Caucasian population, was not previously tested in a Caribbean population. This study found it to be a reliable predictor of in-hospital mortality in a multi-ethnic Trinidadian acute coronary syndrome population, making it a useful risk stratification tool.

ABSTRACT

Objective: To determine whether risk stratification using the Global Registry of Acute Coronary Events (GRACE) risk score is a predictor of in-hospital mortality for ACS patients in a multi-ethnic Caribbean population.

Accepted: 
30 Sep, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Combinaton Therapy in Pulmonary Arterial Hypertension: Single Centre Long-term Experience

Issue: 
DOI: 
10.7727/wimj.2014.148
Pages: 
46–51
Synopsis: 
Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary vascular bed, and right heart failure is the leading cause of death. Treatment with vasoactive agents is crucial for these patient groups. We aimed to evaluate our treatment approach in patients with PAH patients as a tertiary centre.

ABSTRACT

Accepted: 
26 Sep, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Variations of Vascular Endothelial Growth Factor and Pigment Epithelial-derived Factor are Related to Retinopathy of Prematurity in Human Babies

Issue: 
DOI: 
10.7727/wimj.2014.210
Pages: 
251–5
Synopsis: 
Increased expression of vascular endothelial growth factor (VEGF) levels is associated with older postnatal day age. Monitoring of variations in VEGF level and pigment epithelial-derived factor/VEGF ratio might be helpful in predicting the occurrence of retinopathy of prematurity in premature human babies.

ABSTRACT

Background: To examine the role of variations in vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) levels and VEGF/PEDF ratio in predicting the occurrence of retinopathy of prematurity (ROP) in extremely premature human babies.

Accepted: 
17 Sep, 2014
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 12 May, 2015

Cloning and Constructing a Plasmid Encoding Leishmania Eukaryotic Initiation Factor Gene of Leishmania major Fused with Green Fluorescent Protein Gene as a Vaccine Candidate

Issue: 
DOI: 
10.7727/wimj.2014.201
Pages: 
256–9
Synopsis: 
The LeIF gene was cloned into pJET1.2/blunt vector and then it was subcloned into pEGFP-N1 in the upstream of EGFP Gene. The recombinant plasmid could be used as a vaccine candidate against leishmaniasis and EGFP is used as a reporter to detect this protein expression.

ABSTRACT

Objective: Leishmaniasis is usually treated by chemotherapy; however, toxicity, resistance and high-cost limits the use of the chemical drugs. Leishmania eukaryotic initiation factor (LeIF) protein acts the same as interleukin (IL)-12 and reduces the secretion of IL-4 in lymph node cells of mice infected with L major. The aim of this study was cloning of the gene encoding LeIF antigen into eukaryotic expression plasmid pEGFP-N1.

Accepted: 
09 Sep, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Utility of the Tono-Pen in Measuring Intraocular Pressure in Trinidad: A Cross-sectional Study

Issue: 
DOI: 
10.7727/wimj.2014.125
Pages: 
367–71
Synopsis: 
The high specificity and negative predictive value of the Tono-Pen suggests that it is a useful tool requiring minimal training, and can prove beneficial at the primary care level in the exclusion of increased intraocular pressure.

ABSTRACT

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

The Radioprotective Effects of Caffeic Acid Phenethyl Ester and Thymoquinone on Oxidative and Nitrosative Stress in Liver Tissue of Rats Exposed to Total Head Irradiation

Issue: 
DOI: 
10.7727/wimj.2014.176
Pages: 
1–7
Synopsis: 
This study investigates the effects of the addition of caffeic acid phenethyl ester (CAPE) and thymoquinone on oxidative and nitrosative stress in the liver tissue of irradiated rats. Thymoquinone and CAPE decrease oxidative and nitrosative stress markers and have antioxidant effects, which also increase antioxidant capacity in the liver tissue of irradiated rats.

ABSTRACT

Objective: The aim of this study is to investigate the effects of addition of caffeic acid phenethyl ester (CAPE) and thymoquinone (TQ)on oxidative and nitrosative stress in the liver tissue of (IR) irradiated rats.

Methods: Forty Sprague-Dawley rats were divided into five groups to test the radioprotective effectiveness of TQand CAPE administered by intraperitoneal injection. Appropriate control groups were also studied.

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Prevalence of Congenital Malformations in Grenada

Issue: 
DOI: 
10.7727/wimj.2013.331
Pages: 
123–7
Synopsis: 
The prevalence of birth defects in Grenada is low in comparison to Jamaica, as well as other developing and developed countries. Cardiovascular malformations were the most prevalent in this five-year study period.

ABSTRACTS

Objectives: To determine the prevalence of congenital malformations in Grenada for the period January 2000–December 2004.

Revised: 
23 Oct, 2014
Accepted: 
24 Oct, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Aetiology of Paediatric End-stage Renal Failure in Jordan: A Multicentre Study

Issue: 
DOI: 
10.7727/wimj.2014.151
Pages: 
263–6
Synopsis: 
This is the first report on the aetiology of end-stage renal failure in Jordan. The most common aetiologies were congenital anomalies of the kidney and urinary tract, 56.0%, heredofamilial disorders, 23.2%, and glomerulopathies, 22.9%.
ABSTRACT
 
Objective: The purpose of this study was to find out the aetiology of end-stage renal failure (ESRF) in children in Jordan.
 
Accepted: 
11 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 11 May, 2015

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