Original Articles

Total Lymphocyte Count and Haemoglobin Concentration Combined as a Surrogate Marker for Initiating Highly Active Antiretroviral Therapy in a Resource-limited Setting as against CD4 Cell Count

Issue:

Vol 63, Issue 5: Sep (2014)

DOI:

10.7727/wimj.2013.132

Pages:

460–4

Synopsis:

Adding haemoglobin to total lymphocyte count improves the sensitivity of the marker to predict CD4 count <200/mm3, thus ensuring initiation of highly active antiretroviral therapy and thereby reducing investigational costs.

ABSTRACT

Aim: To find a sensitive and low-cost surrogate marker for CD₄ count for initiating highly active antiretroviral therapy (HAART) [CD₄ < 200 /mm³], in the form of total lymphocyte count (TLC) < 1200 /mm³ combined with haemoglobin (Hb) with multiple Hb cut-offs.

Received:

09 Sep, 2013

Accepted:

29 Oct, 2013

PDF Attachment:

dhamangaonkar_et_al-surrogate_markers_for_cd4_count_for_initiating_haart.pdf

Journal Sections:

Original Articles

Keywords:

HIV

Haemoglobin

total lymphocyte count

Journal Authors:

e-Published: 08 May, 2014

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Prevalence and Risk Factors for Intestinal Parasitic Infections in a Rural Community in “Consolación del Sur” Municipality, Cuba

Issue:

Vol 63, Issue 4: Aug (2014)

DOI:

10.7727/wimj.2013.103

Pages:

333–9

Synopsis:

A higher prevalence of protozoa than helminth infection was found and water source was linked with the transmission of protozoan and helminth infection. Detection of intestinal parasitic infections is vital in order to design proper strategies for control in communities.

ABSTRACT

Received:

10 Apr, 2013

Accepted:

23 Apr, 2013

PDF Attachment:

pino_santos_et_al_intestinal_parasitic_infections_in_a_rural_community_in_cuba.pdf

Journal Sections:

Keywords:

Intestinal parasitic infections

Journal Authors:

e-Published: 06 May, 2014

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The Use of Analgesic Drugs in Patients with Sickle Cell Painful Crisis

Issue:

Vol 63, Issue 5: Sep (2014)

DOI:

10.7727/wimj.2012.272

Pages:

479–83

Synopsis:

Painful crisis in patients with sickle cell anaemia is associated with severe pain in 75% and most will require second line therapy for adequate resolution. Physicians need to provide adequate pain relief to decrease morbidity in these patients.

ABSTRACT

Objective: To determine the drug options used for pain in patients with acute sickle cell painful crisis at the University Hospital of the West Indies (UHWI), Jamaica.

Method: This retrospective study assessed all patients admitted to the UHWI between January 1, 2006 and December 31, 2010 with acute sickle cell anaemia painful crisis and the data obtained regarding site, severity, outcome and drug options selected for pain.

Received:

08 Oct, 2012

Revised:

24 Feb, 2013

Accepted:

12 Mar, 2013

PDF Attachment:

boyd_et_al-analgesic_drugs_and_sickle_cell_anaemia.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 30 Apr, 2014

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Site-directed Mutagenesis (Y52E) of POLH Affect Its Ability to Bypass Ultraviolet-induced DNA Lesions in HaCaT Cells

Issue:

Vol 63, Issue 4: Aug (2014)

DOI:

10.7727/wimj.2014.063

Pages:

307–11

Synopsis:

Site-directed mutagenesis (Y52E) of POLH has reduced capacity to bypass ultraviolet-induced DNA lesions in HaCaT cells.

ABSTRACT

Received:

17 Mar, 2014

Accepted:

27 Mar, 2014

PDF Attachment:

luo_et_al-polh_mutation_in_hacat_cells.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 22 Apr, 2014

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Hepatic Lobectomy and Segmental Resection of Liver for Hepatolithiasis

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2013.015

Pages:

174–8

Synopsis:

Hepatectomy is an effective method in the treatment of hepatolithiasis.

ABSTRACT

Received:

18 Jan, 2013

Accepted:

18 Jan, 2013

PDF Attachment:

qiao_et_al-role_of_hepatectomy_in_treating_hepatolithiasis.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 11 Apr, 2014

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Endothelial Injury Preceding Intracranial Aneurysm Formation in Rabbits

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2013.129

Pages:

167–71

Synopsis:

This study is the first to present endothelial cell changes of basilar artery bifurcation in response to sustained high blood flow in rabbits. Endothelial cell impairment possibly initiates aneurysm formation.

ABSTRACT

Objective: This study investigates the change of endothelial cell morphology and function at the rabbit basilar bifurcations in response to sustained high blood flow after bilateral common carotid artery ligation.

Received:

06 May, 2013

Accepted:

14 May, 2013

PDF Attachment:

li_et_al-endothelium_and_intracranial_aneurysm_formation.pdf

Journal Sections:

Original Articles

Keywords:

intracranial aneurysm

Journal Authors:

e-Published: 11 Apr, 2014

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Secondary School Students’ Knowledge of Physical Therapy: The Trinidadian Scenario

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2011.142

Pages:

151–8

Synopsis:

This manuscript examines the accuracy of secondary school students’ knowledge of physical therapy and identified common sources of knowledge. The relationship between source of knowledge, career stream and accuracy of knowledge was examined.

ABSTRACT

Objective: Research in regions outside of the Caribbean shows that high school and college students’ knowledge of physical therapy is lacking. There is no data reported to date for students in the Caribbean region. This study sought to evaluate Trinidadian secondary school students’ knowledge of physical therapy, identify sources of knowledge and examine the relationship between knowledge and selected factors.

Received:

14 Jul, 2011

Accepted:

27 Jul, 2012

PDF Attachment:

roopchand-martin_and_noel-students_knowledge_of_physical_therapy.pdf

Journal Sections:

Original Articles

Keywords:

knowledge

physical therapy

secondary school students

Journal Authors:

S Roopchand-Martin

G Noel

e-Published: 11 Apr, 2014

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Newborn Screening for Sickle Cell Disease in Jamaica: A Review – Past, Present and Future

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2013.107

Pages:

147–50

Synopsis:

Screening newborns for sickle cell disease (SCD) in Jamaica has significantly impacted mortality and morbidity of affected children. Efforts must continue toward the goal of island-wide newborn screening for SCD in order to ensure continued improvements.

ABSTRACT

Received:

12 Apr, 2013

Accepted:

22 Apr, 2013

PDF Attachment:

king_et_al-newborn_screening_for_sickle_cell_disease.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 11 Apr, 2014

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Determination of Chemical Antioxidants and Phenolic Compounds in the Brazilian Mushroom Agaricus sylvaticus

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2011.216

Pages:

142–6

Synopsis:

Agaricus sylvaticus mushroom has been widely studied because of its high nutritional value and medicinal properties. The objective of this study was to evaluate the antioxidant potential of both alcoholic and aqueous extracts of Agaricus sylvaticus, and quantify their total polyphenol content. There is great antioxidant potential of aqueous, alcoholic and ethereal extracts of the Agaricus sylvaticus mushroom.

ABSTRACT

Received:

17 Nov, 2011

Accepted:

17 Jul, 2012

PDF Attachment:

costa_orsine_et_al-antioxidants_and_phenolic_compounds_in_brazilian_mushroom.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 11 Apr, 2014

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A Thirty-year Review of Vulvar Cancer in Jamaica, 1978 to 2007

Issue:

Vol 63, Issue 2: Mar (2014)

DOI:

10.7727/wimj.2013.125

Pages:

134–7

Synopsis:

In Jamaica, squamous cell carcinoma is the most common vulvar cancer, affecting mainly older women. Age-standardized rates for all vulvar cancers and vulvar squamous cell carcinoma are declining.

ABSTRACT

Objective: To evaluate the trends in vulvar cancer between 1978 and 2007 in Kingston and St Andrew, Jamaica, with respect to age-standardized rates and histologic types.

Methods: All cases of vulvar cancer recorded in the Jamaica Cancer Registry from 1978 to 2007 were extracted and analysed for age distribution and histologic type.

Received:

06 May, 2013

Accepted:

30 Jul, 2013

PDF Attachment:

bromfield_et_al-vulvar_cancer.pdf

Journal Sections:

Original Articles

Keywords:

Jamaica

Female genital tract

squamous cell carcinoma