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Original Articles

Factors Associated with High-grade Smear Positivity Levels in Pulmonary Tuberculosis

Issue: 
Vol 69, Issue 6: 2021
DOI: 
10.7727/wimj.2015.600
Pages: 
385-90
Synopsis: 
The present study aimed to investigate the relationship between smear results, the clinical features and the levels of radiological involvement of tuberculosis (TB). The high-grade level of smear acid-resistant bacilli positivity has been linked to increased infectiousness in pulmonary TB.

ABSTRACT

Objective: The high-grade level of smear acid-resistant bacilli (ARB) positivity has been linked to increased infectiousness in pulmonary tuberculosis (TB). The ability to predict infectiousness is important in the management of the disease. The present study aimed to investigate the relationship between smear results, the clinical features, and the levels of radiological involvement of TB.

Received: 
09 Dec, 2015
Accepted: 
22 Apr, 2016
Published: 
10 Dec, 2021
PDF Attachment: 
PDF icon wimj-iss6-2021_385_390.pdf
Journal Sections: 
Original Articles
Keywords: 
cough
pulmonary tuberculosis
radiological involvement
smear positivity grade
symptom.
Journal Authors: 
M Taylan
S Yilmaz
M Demir
H Kaya
HS Sen
M Kabak
C Sezgi
MG Cetincakmak
M Coskunsel
e-Published: 22 Apr, 2016

Design of the Hospital Integrated Information Management System Based on Cloud Platform

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.057
Pages: 
521–6
Synopsis: 
The outdated information management style has become the bottleneck of hospital’s management and development. Hospital integrated information management system based on cloud platform software can optimize integration of hospital information resources and improve the level of standardized management. Meanwhile, the use of the cloud platform will reduce the hospital’s investment in hardware and software.

ABSTRACT

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_521_526.pdf
Journal Sections: 
Original Articles
Keywords: 
management
Hospital
Cloud platform
information technology
Journal Authors: 
L Aijing
Y Jin
e-Published: 18 Apr, 2016

Can the Medical-nursing Combined Care Promote the Accessibility of Health Services for the Elderly in Nursing Home? A Study Protocol of Analysis of the Effectiveness Regarding Health Service Utilization, Health Status and Satisfaction with Care

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.056
Pages: 
514–20
Synopsis: 
This article introduces the study protocol exploring the effectiveness of medical-nursing combined care in China regarding health service use, health status and service satisfaction in a population of the elderly living in nursing homes.

ABSTRACT

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_514_520.pdf
Journal Sections: 
Original Articles
Journal Authors: 
J Bao
X-J Wang
Y Yang
R-Q Dong
Z-F Mao
e-Published: 18 Apr, 2016

Modified Numerical Simulation Model of Blood Flow in Bend

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.054
Pages: 
495–8
Synopsis: 
The modified RNG k-ε model in bend can effectively improve the blood flow's numerical prediction accuracy affected by wall curvature effect, laying the foundation for further research on blood flow in bend.

ABSTRACT

The numerical simulation model of blood flow in bend is studied in this paper. The curvature modification is conducted for the blood flow model in bend to obtain the modified blood flow model in bend. The modified model is verified by U tube. By comparing the simulation results with the experimental results obtained by measuring the flow data in U tube, it was found that the modified blood flow model in bend can effectively improve the prediction accuracy of blood flow data affected by the curvature effect.

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_495_498.pdf
Journal Sections: 
Original Articles
Keywords: 
model
Blood flow
numerical simulation
Journal Authors: 
X Liu
X Zhou
X Hao
X Sang
e-Published: 18 Apr, 2016

Testosterone Level in Testicular Cancer Patients after Chemotherapy

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.060
Pages: 
487–94
Synopsis: 
This study investigated the effects of chemotherapy on testosterone levels in testicular cancer patients. The hormone levels affected due to chemotherapy were differentiated from the effects of the tumour itself by comparing the hormone levels before the onset of chemotherapy to levels measured during and after completion of chemotherapy.

ABSTRACT

Background: The use of chemotherapy for the treatment of cancer began at the start of the 20th century in an attempt to narrow the universe of chemicals that affect the disease. Metastatic testicular cancer has always been sensitive to chemotherapy.  

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_487_494.pdf
Journal Sections: 
Original Articles
Keywords: 
tumour
chemotherapy
testosterone
Testicular cancer
Journal Authors: 
M Sarfraz
Y Ashraf
S Sajid
MA Ashraf
e-Published: 18 Apr, 2016

Combining Diffusion Tensor Imaging and Susceptibility Weighted Imaging on the Substantia Nigra of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-induced Rhesus Monkey Model of Parkinson’s Disease

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.051
Pages: 
480–6
Synopsis: 
Combining the use of diffusion tensor imaging and susceptibility weighted imaging can provide a sensitive method for differentiating between MPTP-induced rhesus monkey model of Parkinson’s disease and wild-type controls.

ABSTRACT

Objective: The aim of this study was to evaluate whether combining diffusion tensor magnetic resonance imaging (DTI) and susceptibility weighted imaging (SWI) techniques would provide a sensitive method for differentiating between 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced rhesus monkey model of Parkinson’s disease (PD) and wild-type controls.

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_480_486.pdf
Journal Sections: 
Original Articles
Keywords: 
Diffusion tensor imaging
Parkinson’s disease
susceptibility weighted imaging
Journal Authors: 
Q Zhang
L Li
B Miao
H Niu
e-Published: 18 Apr, 2016

The Effect and Mechanisms of Proliferative Inhibition of Crocin on Human Leukaemia Jurkat Cells

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.053
Pages: 
473–9
Synopsis: 
Crocin promoted Jurkat cell apoptosis and inhibited cell growth in a dose-time-dependent manner. These results suggest that crocin can be used as a suitable clinical agent for the treatment of T-lineage acute lymphoblastic leukaemia.

ABSTRACT

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_473_479.pdf
Journal Sections: 
Original Articles
Keywords: 
Apoptosis
Anti-tumour
crocin
Jurkat cells
Journal Authors: 
Y Sun
Z Wang
L Wang
L-Z Wang
C Zang
L-R Sun
e-Published: 18 Apr, 2016

Protective Effects of Liquiritin on the Brain of Rats with Alzheimer’s Disease

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.058
Pages: 
468–72
Synopsis: 
Alzheimer’s disease (AD) is clinically manifested by progressive memory damage and cognitive dysfunction. In this study, a rat AD model with liquiritin (LQ) interference was established to observe the effects of LQ on the AD rats’ behavioural memory. The protective and antioxidant effects of LQ improved the rats’ learning and memory ability.

ABSTRACT

Background: Alzheimer’s disease (AD) is a sort of nerve degenerative disease with clinical manifestation of memory damage and cognitive dysfunction. Its typical pathological change is the abnormal deposition of amyloid-beta (Aβ).  

Method: In this study, a rat AD model with liquiritin (LQ) interference was established to observe the effects of LQ on the AD rats’ behavioural memory and primary hippocampus cells.  

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_468_472.pdf
Journal Sections: 
Original Articles
Keywords: 
Alzheimer’s disease
β-amyloid peptide
liquiritin
oxygen radicals
primary hippocampal neurons
Journal Authors: 
X Huang
Y Wang
K Ren
e-Published: 18 Apr, 2016

Nephroprotective Effect of the Leaves of Aloe barbadensis (Aloe Vera) against Toxicity Induced by Diclofenac Sodium in Albino Rabbits

Issue: 
Vol 64, Issue 5: December (2015) – Special Issue on Health Sciences
DOI: 
10.7727/wimj.2016.052
Pages: 
462–7
Synopsis: 
Aloe barbadensis can normalize oxidative stress and can be used as an effective nephroprotective agent against drug-induced nephrotoxicity.
ABSTRACT

Background: The present study was designed to evaluate the nephroprotective effect of the leaves of Aloe barbadensis against toxicity induced by diclofenac sodium in albino rabbits.

Received: 
14 Dec, 2015
Accepted: 
08 Feb, 2016
PDF Attachment: 
PDF icon wimjdec2015_462_467.pdf
Journal Sections: 
Original Articles
Keywords: 
Aloe barbadensis
diclofenac sodium
nephrotoxicity
Journal Authors: 
A Iftikhar
IJ Hasan
M Sarfraz
L Jafri
MA Ashraf
e-Published: 18 Apr, 2016

Porphyromonas gingivalis LPS-induced IL-1β and IL-8 Expression by Reducing MAPK Activation in THP-1 Cells

DOI: 
10.7727/wimj.2016.081
Synopsis: 
The study investigated the inhibitory effects of alpha-mangostin on Porphyromonas gingivalis lipopolysaccharide (LPS)-induced production of pro-inflammatory cytokines and activation of mitogen-activated protein kinase (MAPK) signaling in THP-1 cells. The results indicated that alpha-mangostin suppresses the production of IL-1β and IL-8 in P. gingivalis LPS-stimulated THP-1 cells, possibly by reduction the activation of MAPK pathway. These findings suggest the possible use of alpha-mangostin as an anti-inflammatory agent in adjunctive treatment of periodontitis.

ABSTRACT

Objective:To investigate the inhibitory effects of alpha-mangostin on Porphyromonas gingivalis lipopolysaccharide (LPS)-induced production of pro-inflammatory cytokines and activation of mitogen-activated protein kinase (MAPK) signaling in THP-1 cells.

Received: 
29 Feb, 2016
Accepted: 
31 Mar, 2016
PDF Attachment: 
PDF icon yiemwattana_et_al-suppression_of_il-1v_and_il-8_expression_in_thp-1.pdf
Journal Sections: 
Original Articles
Keywords: 
Alpha-mangostin
IL-1β/8
P. gingivalis LPS
THP-1 cells
Journal Authors: 
I Yiemwattana
R Kaomongkolgit
e-Published: 05 Apr, 2016

Disclaimer

Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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