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Original Articles

Perspectives in Bioethics: Precision Medicine a Threat to Health Equity

DOI: 
10.7727/wimj.2016.074
Synopsis: 
Precision medicine is an important advance that can ameliorate the disease burden in Trinidad and Tobago. This viewpoint highlights some important ethical considerations if precision medicine were to be integrated into the public health care system of Trinidad and Tobago.

ABSTRACT

Received: 
16 Feb, 2016
Accepted: 
07 Jun, 2016
PDF Attachment: 
PDF icon roach_et_al-precision_medicine_and_health_equity.pdf
Journal Sections: 
Original Articles
Keywords: 
Caribbean
Trinidad and Tobago
health equity
precision medicine
Journal Authors: 
A Roach
K Badal
N Sookar
e-Published: 14 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Self-reported Hearing Loss Associated with Frailty among Afro-Caribbeans

Issue: 
Vol 68, Issue 1: 2019
DOI: 
10.7727/wimj.2016.174
Pages: 
29-34
Synopsis: 
This paper investigated the relationship between self-reported hearing loss and frailty in four ethnic groups. Self-reported hearing loss was found to be associated with frailty among Afro-Caribbeans, and this association was largely due to the frailty criterion of exhaustion.

ABSTRACT

Objective: Data on ethnic differences in the relationship between hearing loss and frailty are sparse. We investigated the relationship between self-reported hearing loss and frailty in four ethnic groups.

Received: 
19 Apr, 2016
Accepted: 
25 May, 2016
Published: 
07 Oct, 2019
PDF Attachment: 
PDF icon wimj-iss1-2019_29_34.pdf
Journal Sections: 
Original Articles
Keywords: 
Afro-Caribbean
ethnicity
frailty
hearing loss
Journal Authors: 
MI Naharci
G Engstrom
C Keintz
A Danesh
R Tappen
JG Ouslander
e-Published: 14 Jul, 2016

Acute Pseudomembranous Candidiasis Front at Cleft Lip and Palate: Are There Additional Correlations?

DOI: 
10.7727/wimj.2016.157
Synopsis: 
Cleft lip and palate require in most cases the performance of surgical procedures. During the postoperative periods, there is a greater predisposition to possible episodes by Candida infection. The oral hygiene preventive maneuvers should be strengthened and initiated during infancy.

ABSTRACT

Received: 
08 Apr, 2016
Accepted: 
25 May, 2016
PDF Attachment: 
PDF icon tovani-palone-candidiasis_front_at_cleft_lip_and_palate.pdf
Journal Sections: 
Original Articles
Keywords: 
candidiasis
cleft lip
cleft palate
oral
Journal Authors: 
MR Tovani-Palone
e-Published: 14 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Association between Mannose-Binding Lectin 2 Gene Polymorphism and Liver Fibrosis in Patients with Chronic Viral Hepatitis

Issue: 
Vol 70, Issue 1: 2023
DOI: 
10.7727/wimj.2016.155
Pages: 
7-12
Synopsis: 
In this study, Mannose-Binding Lectin 2 (MBL2) gene polymorphism were investigated in patients with viral Hepatitis B and C. No significant differences in allele frequencies for any polymorphism were observed between patients and controls.

ABSTRACT

Objective: Mannose-binding lectin (MBL) has become a popular molecule in investigations on basic and clinical gastroenterology and contributed to new approaches to the understanding of infectious and immune diseases associated with intestine and liver. The aim of the present study was to investigate the association between codon 54 polymorphisms in MBL2 gene coding MBL and predisposition to fibrosis in patients with viral hepatitis B and C.

Received: 
08 Apr, 2016
Accepted: 
25 May, 2016
Published: 
29 Nov, 2023
PDF Attachment: 
PDF icon wimj-iss1-2023_7_12.pdf
Journal Sections: 
Original Articles
Keywords: 
Fibrosis
hepatitis B
hepatitis C
MBL2 gene
polymorphism.
Journal Authors: 
AT Eminler
M Karkucak
S Gurel
T Ayyildiz
T Gulten
K Irak
T Yakut
e-Published: 14 Jul, 2016

Expectations of Treatment of Hepatitis C in Children

DOI: 
10.7727/wimj.2016.153
Synopsis: 
The study aimed at presenting a general overview of the current treatments for HCV infection in children. In children the most commonly used drugs are pegylated alpha interferon in combination with ribavirin only Boceprevir was tested and not approved for use in children. Safety and efficacy of new drugs in children need further investigation.

ABSTRACT

Background: HCV infection in children differs from infection in adult through transmission paths, spontaneous viral clearance rate, and fibrosis progression duration of chronic infection. It is estimated that the rate of children with chronic hepatitis C will develop cirrhosis is less than 2%, however there are reports of children requiring liver transplantation. 

Received: 
07 Apr, 2016
Accepted: 
25 May, 2016
PDF Attachment: 
PDF icon romero-figueroa-treatment_of_hepatitis_c_in_children.pdf
Journal Sections: 
Original Articles
Keywords: 
treatment
children
hepatitis C
peginterferon
ribavirin
Journal Authors: 
M del Socorro Romero-Figueroa
JR Gamboa-Cardeña
J García-Mena
S Murugesan
AJ Montiel-Jarquín
G Horta-Baas
e-Published: 14 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Immunohistopathological and Biochemical Study of the Effects of Dead Nettle (Urtica Dioica) Extract on Preventing Liver Lesions Induced by Experimental Aflatoxicosis in Rats

Issue: 
Vol 67, Issue 3: 2018
DOI: 
10.7727/wimj.2016.126
Pages: 
254-61
Synopsis: 
This paper studied the preventive effects of dead nettle extract on liver lesions that were induced by experimental aflatoxicosis in rats. According to the biochemical and histopathological findings of the study, antioxidant system activity increased and lipid peroxidation and liver enzyme levels decreased in the group that received dead nettle leaf extract. As a result, it could be concluded that dead nettle leaf extract had hepatoprotective effects against aflatoxicosis.

ABSTRACT

Objective: Aflatoxicosis is a mycotoxicosis infection with an acute or chronic course that forms due to aflatoxins (AFs) in humans and animals. Aflatoxins primarily affect the liver and can lead to histopathological necrosis, fibrosis and hepatocarcinogenesis of the organ. This paper studied the preventive effects of dead nettle leaf (Urtica dioica leaf; UDL) extract on liver lesions that were induced by experimental aflatoxicosis in rats.

Received: 
22 Mar, 2016
Accepted: 
25 May, 2016
Published: 
14 Nov, 2018
PDF Attachment: 
PDF icon wimj-iss3-2018_254_261.pdf
Journal Sections: 
Original Articles
Keywords: 
Aflatoxicosis
extract of dead nettle leaf
liver lesions
rat
Journal Authors: 
S Yıldırım
Z Yener
e-Published: 13 Jul, 2016

Tracheal Intubation Using Trueview® Videolaryngoscopy Versus Direct Macintosh® Laryngoscopy: An observational, Case-control Study

DOI: 
10.7727/wimj.2015.597
Synopsis: 
Videolaryngoscopy is a method of tracheal intubation which is mainly used for the difficult airway. Its superiority and safety over direct laryngoscopy makes it a more appropriate tool for routine tracheal intubation.

ABSTRACT

Background: The main objective of this study is to evaluate the effectiveness of videolaryngoscopy, performed with the help of Trueview® device, for routine oro-tracheal intubations compared with visualization by direct laryngoscopy, performed with McIntosh laryngoscope.

Received: 
09 Dec, 2015
Revised: 
17 May, 2016
Accepted: 
25 May, 2016
PDF Attachment: 
PDF icon szederjesi_et_al-direct_laryngoscopy_versus_videolaringoscopy.pdf
Journal Sections: 
Original Articles
Keywords: 
Difficult airway
difficult intubation
direct laryngoscopy
videolaryngoscopy
Journal Authors: 
J Szederjesi
A Lazar
A Szabo
A Emoke
SM Copotoiu
L Azamfirei
e-Published: 12 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Distribution of Bcl-2 in Odontogenic Cyst and Tumours: Histochemical Study

DOI: 
10.7727/wimj.2015.579

ABSTRACT

Introduction: The Odontogenic Keratocyst is known for its aggressiveness, high recurrence rate and transformation of keratinized epithelia to non-keratinized squamous epithelium for which inflammation has been suggested to be responsible. bcl-2 an anti-apoptotic protein, prolongs the life span of epithelial cells and allows proliferation, differentiation and morphogenesis.

Received: 
24 Nov, 2015
Accepted: 
14 Jun, 2016
PDF Attachment: 
PDF icon phull_et_al-bcl-2_in_odontogenic_cyst_and_tumour.pdf
Journal Sections: 
Original Articles
Keywords: 
Apoptosis
Ameloblastoma
bcl-2
keratocystic odontogenic tumor
radicular cyst
Journal Authors: 
K Phull
R Metgud
S Patel
e-Published: 12 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Laparoscopic Pancreaticoduodenectomy - Experiences of 40 Cases

DOI: 
10.7727/wimj.2016.119
Synopsis: 
Laparoscopic pancreaticoduodenectomy (LPD) was still one of the most challenging endoscopic surgeries by far and there were still some technical problems to be resolved. In this study, we try to investigate the difficulties and countermeasures of the LPD using a retrospective analysis for the surgical techniques of the LPD carried out for 40 patients in our hospital from December 2009 to Jul 2015 and the clinical data such as operative time, intra-operative blood loss, numbers of scavenged lymph node and postoperative complications were collected. The result showed that application of appropriate surgical approach, improvement of the resection of UP and modification of the pancreaticojejunostomy(PJ) could make the LPD easier and safer.

ABSTRACT

Background: Laparoscopic pancreaticoduodenectomy (LPD) was still one of the most challenging endoscopic surgeries by far and there were still some technical problems to be resolved. In this study, we try to investigate the difficulties and countermeasures of the LPD.

Received: 
21 Mar, 2016
Accepted: 
25 May, 2016
PDF Attachment: 
PDF icon wang-laparoscopic_pancreaticoduodenectomy.pdf
Journal Sections: 
Original Articles
Keywords: 
laparoscopy
pancreaticoduodenectomy
pancreaticojejunostomy surgical approach
Journal Authors: 
X Wang
e-Published: 11 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Systematic Review and Meta-Analysis of Published Literatures: How Much do We Know about Reliable Prevalence of Leptospirosis in Iran?

DOI: 
10.7727/wimj.2016.112
Synopsis: 
This is a first comprehensive study about the prevalence of leptospirosis in Iran. Although the highest prevalence of leptospirosis was observed in Mazandaran province, interestingly, the lowest prevalence was observed in the neighboring province, Gilan.

ABSTRACT

Received: 
11 Mar, 2016
Accepted: 
25 Jul, 2016
PDF Attachment: 
PDF icon khayat_et_al-prevalence_of_leptospirosis_in_iran.pdf
Journal Sections: 
Original Articles
Keywords: 
meta-analysis
Iran leptospirosis
Journal Authors: 
H Khayat
K Sayehmiri
F Sayehmiri
S Ghafourian
M Rezapour
A Sheikhian
L Bogdanovic
M Taherikalani
e-Published: 07 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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