Original Articles

DNA Release and Uptake Associated with the Development of Pleomorphic Cells in Mammalian Skin Autotransplants

Issue:

Vol 60, Issue 3 (2011)

Pages:

257–62

Synopsis:

DNA release and uptake in an in vivo mammalian system is described for the first time, and is related to normal growth and differentiation, abnormal growth and cancer. It is proposed that there is a homeostatic exchange system of intercellular factors including genetic material (DNA/RNA) between cells and tissues, important for growth and differentiation. Disturbances of the messages or the homeostatic control of the exchange system can result in abnormal growth and cancer.

ABSTRACT

Objective: Although several in vitro studies have demonstrated active release of DNA by living cells, there is still doubt. There are no such in vivo studies (1). The following experiment is an in vivo study to determine whether DNA release and uptake by cells and tissues occur and can be related to normal growth and differentiation, abnormal growth and cancer.

PDF Attachment:

dr_wg_chen.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

cancer

cellular and genetic factors

growth and differentiation

intercellular exchange

Journal Authors:

WG Chen

e-Published: 29 Jan, 2014

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Chronic Disease in the Caribbean: Strategies to Respond to the Public Health Challenge in the Region What Can We Learn from Jamaica’s Experience?

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

397–411

Synopsis:

This paper reviews the burden of chronic non-communicable diseases (CNCDs) in the Caribbean within the framework of the global burden of CNCDs and provides recommendations for strategies to combat the epidemic within the region.

ABSTRACT

PDF Attachment:

dr_ferguson-1_chronic_disease_in_the_caribbean.qxd_.pdf

Journal Sections:

Keywords:

chronic non-communicable disease

public health interventions

Journal Authors:

e-Published: 29 Jan, 2014

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Study of Promoter and Structural Gene Sequence of whiB7 in MDR and XDR forms of Mycobacterium tuberculosis

Issue:

Vol 60, Issue 3 (2011)

Pages:

251–6

Synopsis:

The present work is the first study on the sequence of whiB7 gene in susceptible, MDR and XDR clinical isolates. No mutation was found in this gene in strains isolated from tuberculosis patients and it was shown that the promoter and structural gene of whiB7 are highly conservative in XDR and MDR isolates. This finding confirmed the need for further studies on designing a proper inhibitor for conservative WhiB7 protein in clinical forms of M tuberculosis.

ABSTRACT

PDF Attachment:

dr_m_arjomandzadegan.qxd_.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 29 Jan, 2014

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Chronic Non-Communicable Diseases and the Economy

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

392–6

Synopsis:

This paper attempts to explain how chronic noncommunicable diseases affect the functioning of the economic system and how the working of the economy in turn influences the incidence of CNCDs in particular countries. Suggestions are then given regarding the alignment of economic and health policies to support the prevention and management imperatives presented by the CNCDs.

INTRODUCTION

PDF Attachment:

dr_theodore.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

chronic non-communicable diseases

economic system

Journal Authors:

K Theodore

e-Published: 29 Jan, 2014

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From Port-of-Spain Summit to United Nations High Level Meeting: CARICOM and the Global Non-communicable Disease Agenda

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

387–91

Synopsis:

CARICOM convened the only Heads of Government Non-communicable Diseases Summit and then successfully advocated for the global-level United Nations High Level Meeting on NCDs in September 2011. Implementation of the Port-of-Spain NCD Declaration is related to population size and regional supports.

ABSTRACT

PDF Attachment:

dr_samuels.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

chronic non-communicable diseases

Journal Authors:

e-Published: 29 Jan, 2014

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The Road to the United Nations High Level Meeting on Chronic Non-communicable Diseases

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

384–6

Synopsis:

The United Nations High Level Meeting (UNHLM) will be an historic event where world leaders will address the increasing global burden of non-communicable diseases (NCDs). Its mandate is ‘to address the prevention and control of non-communicable diseases worldwide, with a particular focus on developmental and other challenges, and social and economic impacts, particularly for developing countries’. The Caribbean has played a leadership role in convening the UNHLM and, as a region significantly impacted by the NCD epidemic, may potentially benefit from the meeting outcomes.

ABSTRACT

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Journal Sections:

Keywords:

United Nations High Level Meeting

Journal Authors:

T Hassell

A Hennis

e-Published: 29 Jan, 2014

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The Effect of Impaired Sleep on Preterm Labour

Issue:

Vol 63, Issue 1: Jan (2014)

DOI:

10.7727/wimj.2012.305

Pages:

62–7

Synopsis:

Early diagnosis and management may decrease the adverse outcomes associated with sleep disorder during pregnancy.

ABSTRACT

Background: Sleep disturbance has become an important health problem for pregnant women. In fact, pregnancy-associated sleep disorder has been recognized as a distinct clinical entity. We aimed to study the relationship between sleep disturbance and preterm birth during pregnancy in a sample of Iranian women.

Received:

26 Nov, 2012

Accepted:

29 May, 2013

PDF Attachment:

dolatian_et_al-effect_of_impaired_sleep_on_preterm_labour.pdf

Journal Sections:

Original Articles

Keywords:

pregnancy

Epworth Sleepiness Scale (ESS)

Insomnia Severity Index (ISI)

Journal Authors:

e-Published: 29 Jan, 2014

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Hypothalamic-pituitary-ovarian Axis in Thyroid Dysfunction

Issue:

Vol 62, Issue 9: Dec (2013)

DOI:

10.7727/wimj.2013.038

Synopsis:

Findings from this study suggest that impairment of reproductive function associated with thyroid dysfunction is in attendant with derangement of hormonal milieu and alteration in reproductive organs cytoarchitecture. Luteinizing hormone and oestradiol are implicated.

ABSTRACT

Background: It has been established that thyroid dysfunction causes impairment of reproductive function. However, laboratory and human studies that associated this with female reproductive hormones are conflicting and data reporting the effects of thyroid dysfunction on reproductive organs are insufficient.

Received:

20 Feb, 2013

Accepted:

22 Apr, 2013

PDF Attachment:

ajayi_et_al-hypothalamic-pituitary-ovarian_axis.pdf

Journal Sections:

Keywords:

follicle stimulating hormone

Journal Authors:

e-Published: 24 Jan, 2014

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Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Evolution of Blood Donation Patterns in a Hospital-based Blood Centre over a Seven-year Period: Implications for Donor Recruitment and Retention

Issue:

Vol 62, Issue 7: Sept (2013)

DOI:

10.7727/wimj.2012.204

Pages:

632–5

Synopsis:

Based on a comparative study of blood donation over a seven-year period, it is evident that innovative methods of donor recruitment are necessary if the blood supply is to keep pace with the increasing demand.

ABSTRACT

Objective: The aim of this study is to investigate the effect of a public appeal to encourage voluntary blood donation by comparing the pattern of blood donations in 2000 and 2007.

Received:

09 Jul, 2012

Accepted:

14 Dec, 2012

PDF Attachment:

dr_lm_buchner-daley_wimj.september.qxd_.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 22 Jan, 2014

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Prevalence of Depression in Type 2 Diabetic Patients in Trinidad and Tobago

Issue:

Vol 62, Issue 7: Sept (2013)

DOI:

10.7727/wimj.2012.329

Pages:

628–31

Synopsis:

The prevalence of depression in Type 2 diabetic patients was 17.9%. Females and patients with co-existing medical complications had higher levels of depression. It is recommended that psychological screening be done at diabetic health clinics to aid in better control, quality of life and longevity.

ABSTRACT

Background: Depression is a common problem among those suffering from diabetes mellitus. The dual diagnoses of a chronic medical disease and mental disorder, symptomatic presentation and stringent treatment regimen are sources of psychological distress for patients and present a major challenge for healthcare workers.

Received:

18 Dec, 2012

Accepted:

19 Feb, 2013

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Journal Sections:

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