Original Articles

Study on Vascular Endothelial Growth Factor and Its Receptor in the Vitreous of Diabetic Rats

Issue:

Vol 62, Issue 9: Dec (2013)

DOI:

10.7727/wimj.2013.144

Synopsis:

The changes of vascular endothelial growth factor (VEGF) and kinase insert domain-containing receptor (KDR) levels in the vitreous of diabetic rats were related to the early retinopathy induced by diabetes.

ABSTRACT

Objective: To investigate the vitreous level of vascular endothelial growth factor (VEGF) and kinase insert domain-containing receptor (KDR) in diabetic rats, and to explore the role of VEGF and KDR in diabetic retinopathy.

Received:

07 May, 2013

Accepted:

17 May, 2013

PDF Attachment:

zhang_et_al-vegf_and_kdr_in_diabetic_retinopathy.pdf

Journal Sections:

Original Articles

Keywords:

Diabetic rat models

kinase insert domain-containing receptor (KDR)

vascular endothelial growth factor (VEGF)

Journal Authors:

e-Published: 30 Jan, 2014

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Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Taming the Burgeoning Stroke Epidemic in Africa: Stroke Quadrangle to the Rescue

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

412–21

Synopsis:

Africa bears a heavy burden of stroke. In this paper, a stroke quadrangle is proposed comprising demographic surveillance and stroke research network, integrated community-based primary and secondary prevention programmes, easily accessible and wellequipped acute stroke care services and neuro-rehabilitation centres and services.

ABSTRACT

Objectives: Globally, stroke is the second leading cause of death. This is a systematic review of the existing literature to examine the burden and profile of stroke in the World Health Organization (WHO) African region and proffer coordinated and responsive means to tackle the epidemic.

PDF Attachment:

Journal Sections:

Keywords:

Journal Authors:

e-Published: 29 Jan, 2014

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DNA Release and Uptake Associated with the Development of Pleomorphic Cells in Mammalian Skin Autotransplants

Issue:

Vol 60, Issue 3 (2011)

Pages:

257–62

Synopsis:

DNA release and uptake in an in vivo mammalian system is described for the first time, and is related to normal growth and differentiation, abnormal growth and cancer. It is proposed that there is a homeostatic exchange system of intercellular factors including genetic material (DNA/RNA) between cells and tissues, important for growth and differentiation. Disturbances of the messages or the homeostatic control of the exchange system can result in abnormal growth and cancer.

ABSTRACT

Objective: Although several in vitro studies have demonstrated active release of DNA by living cells, there is still doubt. There are no such in vivo studies (1). The following experiment is an in vivo study to determine whether DNA release and uptake by cells and tissues occur and can be related to normal growth and differentiation, abnormal growth and cancer.

PDF Attachment:

dr_wg_chen.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

cancer

cellular and genetic factors

growth and differentiation

intercellular exchange

Journal Authors:

WG Chen

e-Published: 29 Jan, 2014

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Chronic Disease in the Caribbean: Strategies to Respond to the Public Health Challenge in the Region What Can We Learn from Jamaica’s Experience?

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

397–411

Synopsis:

This paper reviews the burden of chronic non-communicable diseases (CNCDs) in the Caribbean within the framework of the global burden of CNCDs and provides recommendations for strategies to combat the epidemic within the region.

ABSTRACT

PDF Attachment:

dr_ferguson-1_chronic_disease_in_the_caribbean.qxd_.pdf

Journal Sections:

Keywords:

chronic non-communicable disease

public health interventions

Journal Authors:

e-Published: 29 Jan, 2014

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Study of Promoter and Structural Gene Sequence of whiB7 in MDR and XDR forms of Mycobacterium tuberculosis

Issue:

Vol 60, Issue 3 (2011)

Pages:

251–6

Synopsis:

The present work is the first study on the sequence of whiB7 gene in susceptible, MDR and XDR clinical isolates. No mutation was found in this gene in strains isolated from tuberculosis patients and it was shown that the promoter and structural gene of whiB7 are highly conservative in XDR and MDR isolates. This finding confirmed the need for further studies on designing a proper inhibitor for conservative WhiB7 protein in clinical forms of M tuberculosis.

ABSTRACT

PDF Attachment:

dr_m_arjomandzadegan.qxd_.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 29 Jan, 2014

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Chronic Non-Communicable Diseases and the Economy

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

392–6

Synopsis:

This paper attempts to explain how chronic noncommunicable diseases affect the functioning of the economic system and how the working of the economy in turn influences the incidence of CNCDs in particular countries. Suggestions are then given regarding the alignment of economic and health policies to support the prevention and management imperatives presented by the CNCDs.

INTRODUCTION

PDF Attachment:

dr_theodore.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

chronic non-communicable diseases

economic system

Journal Authors:

K Theodore

e-Published: 29 Jan, 2014

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From Port-of-Spain Summit to United Nations High Level Meeting: CARICOM and the Global Non-communicable Disease Agenda

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

387–91

Synopsis:

CARICOM convened the only Heads of Government Non-communicable Diseases Summit and then successfully advocated for the global-level United Nations High Level Meeting on NCDs in September 2011. Implementation of the Port-of-Spain NCD Declaration is related to population size and regional supports.

ABSTRACT

PDF Attachment:

dr_samuels.qxd_.pdf

Journal Sections:

Original Articles

Keywords:

chronic non-communicable diseases

Journal Authors:

e-Published: 29 Jan, 2014

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The Road to the United Nations High Level Meeting on Chronic Non-communicable Diseases

Issue:

Vol 60, Issue 4 (2011) - Special Issue on WIMJ 60th Anniversary, 1951-2011

Pages:

384–6

Synopsis:

The United Nations High Level Meeting (UNHLM) will be an historic event where world leaders will address the increasing global burden of non-communicable diseases (NCDs). Its mandate is ‘to address the prevention and control of non-communicable diseases worldwide, with a particular focus on developmental and other challenges, and social and economic impacts, particularly for developing countries’. The Caribbean has played a leadership role in convening the UNHLM and, as a region significantly impacted by the NCD epidemic, may potentially benefit from the meeting outcomes.

ABSTRACT

PDF Attachment:

Journal Sections:

Keywords:

United Nations High Level Meeting

Journal Authors:

T Hassell

A Hennis

e-Published: 29 Jan, 2014

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The Effect of Impaired Sleep on Preterm Labour

Issue:

Vol 63, Issue 1: Jan (2014)

DOI:

10.7727/wimj.2012.305

Pages:

62–7

Synopsis:

Early diagnosis and management may decrease the adverse outcomes associated with sleep disorder during pregnancy.

ABSTRACT

Background: Sleep disturbance has become an important health problem for pregnant women. In fact, pregnancy-associated sleep disorder has been recognized as a distinct clinical entity. We aimed to study the relationship between sleep disturbance and preterm birth during pregnancy in a sample of Iranian women.

Received:

26 Nov, 2012

Accepted:

29 May, 2013

PDF Attachment:

dolatian_et_al-effect_of_impaired_sleep_on_preterm_labour.pdf

Journal Sections:

Original Articles

Keywords:

pregnancy

Epworth Sleepiness Scale (ESS)

Insomnia Severity Index (ISI)

Journal Authors:

e-Published: 29 Jan, 2014

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Hypothalamic-pituitary-ovarian Axis in Thyroid Dysfunction

Issue:

Vol 62, Issue 9: Dec (2013)

DOI:

10.7727/wimj.2013.038

Synopsis:

Findings from this study suggest that impairment of reproductive function associated with thyroid dysfunction is in attendant with derangement of hormonal milieu and alteration in reproductive organs cytoarchitecture. Luteinizing hormone and oestradiol are implicated.

ABSTRACT

Background: It has been established that thyroid dysfunction causes impairment of reproductive function. However, laboratory and human studies that associated this with female reproductive hormones are conflicting and data reporting the effects of thyroid dysfunction on reproductive organs are insufficient.

Received:

20 Feb, 2013

Accepted:

22 Apr, 2013

PDF Attachment:

ajayi_et_al-hypothalamic-pituitary-ovarian_axis.pdf

Journal Sections:

Keywords:

follicle stimulating hormone

Journal Authors:

e-Published: 24 Jan, 2014

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Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

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The University of the West Indies, Mona

West Indian Medical Journal
ISSN: 2309-5830

Study on Vascular Endothelial Growth Factor and Its Receptor in the Vitreous of Diabetic Rats

Pre-published Manuscript

Taming the Burgeoning Stroke Epidemic in Africa: Stroke Quadrangle to the Rescue

DNA Release and Uptake Associated with the Development of Pleomorphic Cells in Mammalian Skin Autotransplants

Chronic Disease in the Caribbean: Strategies to Respond to the Public Health Challenge in the Region What Can We Learn from Jamaica’s Experience?

Study of Promoter and Structural Gene Sequence of whiB7 in MDR and XDR forms of Mycobacterium tuberculosis

Chronic Non-Communicable Diseases and the Economy

From Port-of-Spain Summit to United Nations High Level Meeting: CARICOM and the Global Non-communicable Disease Agenda

The Road to the United Nations High Level Meeting on Chronic Non-communicable Diseases

The Effect of Impaired Sleep on Preterm Labour

Hypothalamic-pituitary-ovarian Axis in Thyroid Dysfunction

Pre-published Manuscript

Pages

West Indian Medical Journal

Online Systems

Student Services

Registration & Fees

Online Support

West Indian Medical JournalISSN: 2309-5830